Browsing Research Articles (Pharmacology) by Title

Browsing Research Articles (Pharmacology) by Title

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  • Targeting specific checkpoints in the management of SARS-CoV-2 induced cytokine storm 
    Abubakar, Abdullahi Rabiu; Ahmad, Rahnuma; Rowaiye, Adekunle Babajide; Rahman, Sayeeda; Iskandar, Katia; Dutta, Siddhartha; Oli, Angus Nnamdi; Dhingra, Sameer; Tor, Maryam Abba; Etando, Ayukafangha; Kumar, Santosh; Irfan, Mohammed; Gowere, Marshall; Chowdhury, Kona; Jahan, Dilshad; Schellack, Natalie; Haque, Mainul (MDPI, 2022-03-25)
    COVID-19-infected patients require an intact immune system to suppress viral replication and prevent complications. However, the complications of SARS-CoV-2 infection that led to death were linked to the overproduction ...
  • Teaching pharmacology online : not just another narration 
    Cordier, Werner; Lubbe, J.C. (Irene) (Health and Medical Publishing Group, 2021-09)
    The COVID-19 pandemic placed educators in unique circumstances, not only due to their discipline- and student-specific considerations, but also their personal and professional milieu. Given a series of sudden ...
  • This too shall pass : coronaphobia and other fears 
    Outhoff, Kim (Medpharm Publications, 2020-06)
    “The heart's memory eliminates the bad and magnifies the good, and thanks to this artifice, we manage to endure the burden of the past.” Gabriel García Márquez, 1985, Love in the Time of Cholera.
  • To clot, or not to clot –antithrombotic therapy is the question 
    Osuch, Elzbieta; Marais, Andre (AOSIS Open Journals, 2019)
    Haemostasis and thrombosis rely on three components namely the vascular endothelial wall, blood platelets and the coagulation cascade. Non-physiologic excessive thrombosis occurs when haemostatic processes are dysfunctional, ...
  • Toxicity profile of pyrrolizidine alkaloid-containing medicinal plants : Emphasis on Senecio species 
    Neuman, Manuela G.; Steenkamp, Vanessa (Global Science Books, 2009-12)
    Please read abstract in article.
  • Toxicity testing of two medicinal plants, Bridelia micrantha and Antidesma venosum 
    Steenkamp, Vanessa; Mokoele, T.L.; Jansen van Rensburg, Connie E. (Bentham Science, 2009)
    A. venosum and B. micrantha are widely used ethnomedically and B. micrantha has furthermore indicated the potential to be developed into a drug due to the various biological activities previously reported. However, the ...
  • Treatment of acute wounds and injuries : cuts, bites, bruises and sprains 
    Mlambo, Shamiso Shelter; Parkar, Hafiza; Naude, L.; Cromarty, Allan Duncan (Medpharm Publications, 2022)
    Acute wounds and injuries are a common daily occurrence, and their appropriate care is critical to healing. In South Africa, community pharmacists are often the first to encounter acute wounds and injuries such as cuts, ...
  • Treatment of the common cold with herbs used in Ayurveda and Jamu : monograph review and the science of ginger, liquorice, turmeric and peppermint 
    Wardani, Retno S.; Schellack, Natalie; Govender, Tamlyn; Dhulap, Abhay N.; Utami, Prapti; Malve, Vinod; Wong, Yong Chiat (Bioexcel Publishing, 2023-06)
    BACKGROUND : The common cold is typically managed with decongestants, antihistamines, antitussives and antipyretics. In addition to these established medications, herbal ingredients have been used over centuries to help ...
  • Trends in pharmacotherapy selection for the treatment of alcohol withdrawal in the Free State Province, South Africa 
    Van Zyl, P.M.; Gagiano, C.A.; Mollentze, W.F.; Snyman, J.S.; Joubert, G. (Psychological Society of South Africa, 2013-11)
    BACKGROUND. The selection of pharmacotherapy for the treatment of alcohol withdrawal remains a clinical challenge. Research continues into the underlying pathophysiology of dependence and withdrawal. A spectrum of clinical ...
  • Tricarbonyl(ŋ 6-flavone)chromium(0) 
    Van Tonder, Johannes H.; Bezuidenhoudt, Barend C.B.; Janse van Rensburg, J. Marthinus (International Union of Crystallography, 2009-11)
    In the title compound, [Cr(C15H10O2)(CO)3], the Cr(CO)3 unit exhibits a three-legged piano-stool conformation. The chromium metal centre is coordinated by the phenyl ring of the flavone ligand [Cr-(phenyl centroid) distance ...
  • Tricarbonyl(ŋ6-4′,7-dimethoxyiso-flavone) chromium(0) 
    Van Tonder, Johannes H.; Bezuidenhoudt, Barend C.B.; Janse van Rensburg, J. Marthinus (International Union of Crystallography, 2009)
    The metal atom of the Cr(CO)3 unit of the title compound, [Cr(C17H14O4)(CO)3], is coordinated to the methoxyphenyl ring of the isoflavone ligand; the Cr(CO)3 unit exhibits a three-legged piano-stool conformation. The ...
  • Undergraduate antibiotic stewardship training : are we leaving our future prescribers ‘flapping in the wind’? 
    Adriaan, Brink; Schoeman, Johan P.; Muntingh, George L. (Health and Medical Publishing Group, 2017-05)
    A multisite survey of South African (SA) medical students’ perceptions and knowledge of antibiotic resistance (ABR) and appropriate prescribing by Wasserman et al., published in this edition of the SAMJ, demonstrates ...
  • Underlying causes of chronic bladder dysfunction 
    Marais, Andre; Osuch, Elzbieta (Medpharm Publications, NISC (Pty) Ltd and Cogent, Taylor and Francis Group, 2018)
    General practitioners and family physicians frequently encounter patients suffering from voiding disorders. Various underlying causes such as spinal cord injury, cerebrovascular accidents, traumatic brain injury and several ...
  • Underlying mechanisms of cytotoxicity in HepG2 hepatocarcinoma cells exposed to arsenic, cadmium and mercury individually and in combination 
    Cordier, Werner; Yousaf, Muhammad; Nell, Margo Judith; Steenkamp, Vanessa (Elsevier, 2021-04)
    BACKGROUND : Toxicity data regarding combinational exposure of humans to arsenic, cadmium and mercury is scarce. Although hepatotoxicity has been reported, limited information is available on their mechanistic underpinnings. ...
  • An update on available pain medications 
    Osuch, Elzbieta; Marais, Andre (Medpharm Publications, NISC (Pty) Ltd and Cogent, Taylor and Francis Group, 2018)
    Pain is a complex interaction of sensory, emotional and behavioural factors. Chronic pain is among the most common reasons for seeking medical attention. In contrast to acute pain, where the goal is primary pain relief, ...
  • An update on the pharmacology of anxiolytics for the anxiety, obsessive compulsive and post-traumatic stress disorders 
    Outhoff, Kim (MedPharm Publications, 2016)
    The anxiety disorders, obsessive compulsive disorder (OCD) and post-traumatic stress disorder (PTSD) are common and debilitating, often coexist with medical and psychiatric conditions, and usually require long-term ...
  • Urinary tract infections in children 
    Osuch, Elzbieta; Marais, Andre (Medpharm Publications, NISC (Pty) Ltd and Cogent, Taylor and Francis Group, 2018)
    Urinary tract infections (UTIs) are common in childhood and represent approximately 10% of hospital-acquired infections. It is clinically challenging to distinguish cystitis (lower UTI) from pyelonephritis (upper UTI) in ...
  • The use of methylphenidate as a cognitive enhancer by Health Sciences students at a South African university : a pilot study  
    Marais, Andre; Steenkamp, Vanessa; Kok, Elandre (Open Journal Systems, 2017-07-07)
    BACKGROUND : The incremental off-label use of methylphenidate by students to enhance cognitive performance has been widely described in international studies. Recent local media reports have suggested a similar trend in ...
  • Use of Yokukansan (TJ-54) in the treatment of neurological disorders : a review 
    De Caires, S.; Steenkamp, Vanessa (John Wiley & Sons, 2010-09)
    Kampo herbal remedies are reported to have a wide range of indications and have attracted attention due to reports suggesting that these remedies are effective when used in disease treatment while maintaining a favourable ...
  • User, beware! 
    Marais, Andre (Plus 50 Media (Pty) Ltd, 2017-12)
    Patients who are treated for depression or insomnia should always be conscious of the implications of taking prescribed medications, although these could improve your quality of life significantly