Browsing Research Articles (Pharmacology) by Title

Browsing Research Articles (Pharmacology) by Title

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  • Lepule, Keagile Hilda; Cordier, Werner; Steenkamp, Paul; Nell, Margo Judith; Steenkamp, Vanessa (Elsevier, 2019-11)
    Parkinson’s disease, characterised by loss of dopaminergic neurons in the substantia nigra of the brain, is attributed to oxidative stress and mitochondrial dysfunction. As no cure is available, and dopamine-replacement ...
  • Outhoff, Kim (Medpharm, 2014)
    Acute non-specific low back pain, usually a result of muscle strains and ligament sprains from lifting, exercising or moving unexpectedly, is commonly encountered in primary care. At any given time, approximately one in ...
  • Marais, Andre (MedPharm Publications, 2016)
    Gastro-oesophageal reflux disease (GORD) is a common condition worldwide. It is characterised by numerous upper gastrointestinal tract symptoms, but patients mainly present with heartburn and regurgitation. Various causes ...
  • Gulumian, Mary; Yahaya, Ewura Seidu; Steenkamp, Vanessa (Hindawi, 2018-11-22)
    The use of traditional herbal remedies as alternativemedicine plays an important role in Africa since it forms part of primary health care for treatment of various medical conditions, including wounds. Although physiological ...
  • Outhoff, Kim (South African Academy of Family Practice/Primary Care, 2012)
    Agomelatine is a novel melatonergic antidepressant that restores disrupted biological rhythms, essentially by resetting the circadian clock. Two different, non-monoaminergic, and possibly synergistic pathways, appear to ...
  • Marais, Andre (Medpharm Publications, NISC (Pty) Ltd and Cogent, Taylor & Francis Group, 2016)
    Allergic conjunctivitis is a common condition encountered by the healthcare professional. Several factors have been implicated as possible causes and almost all involve an IgE mediated immune response. Symptoms may vary ...
  • Sommers, De K. (MedPharm Publications, 2015)
  • Muntingh, George L. (MedPharm Publications, 2016)
    Chronic obstructive pulmonary disease (COPD) is characterised by chronically poor air flow. Typically, it worsens over time. The main symptoms include shortness of breath, coughing and sputum production. Most people with ...
  • Marais, Andre (Plus 50 Media (Pty) Ltd., 2015-05)
    The signs and symptoms of Alzheimer's disease differ from normal age-related changes. Declining memory starts from around 40, and it is normal to experience changes in memory as you grow older, but memory loss that disrupts ...
  • Greeff, O.B.W. (Oppel Bernhardt Wilhelm), 1948- (OpenJournals, 2009-09)
    21 September 2009 is hailed as World Alzheimer's Day, creating awareness for the most common type of all the dementias. Senile dementia of the Alzheimer's type (SDAT) has a four to five year survival rate if a patient is ...
  • Horvath, Ulrike E.I.; Dobrzanska, Liliana; Strasser, Christoph E.; Bouwer, Wilna; Joone, Gisela Käthe; Jansen van Rensburg, Constance Elizabeth; Cronje, Stephanie; Raubenheimer, Helgard G. (Elsevier, 2012-06)
    A series of new neutral mononuclear or dinuclear gold(I) complexes and a cyclic cationic tetranuclear amidogold(I) complex comprising of the phosphines 1,2- bis(dimethylphosphino)ethane (dmpe), μ-1,2–bis(diphenylphosphino)ethane ...
  • Muntingh, George L.; Viljoen, M. (Medpharm Publications, NISC (Pty) Ltd and Cogent, Taylor and Francis Group, 2017)
    Despite some modest improvements described recently, anaemia remains a significant global public health concern affecting both developed and developing countries. It affects a quarter of the global population, including ...
  • Makkink, Jaco L.; Greeff, O.B.W. (Oppel Bernhardt Wilhelm), 1948- (Health and Medical Publishing Group, 2014-04)
    BACKGROUND. Hypertension poses a huge financial risk to any funder/medical aid, including the risk-mitigating strategies provided by the managed care organisations that are required to manage patients with hypertension. ...
  • Jansen van Rensburg, Connie E. (Wiley, 2015-06)
    Humic substances are effective in the suppression of delayed type hypersensitivity, rat paw oedema, a graftversus- host reaction and contact hypersensitivity in rats. They reduce the C-reactive protein levels of ...
  • Komolafe, Ayoola Oluwakayode; Ally, Mahmood Moosa Tar Mahomed; Van Tonder, Jacob John; Greeff, O.B.W. (Oppel Bernhardt Wilhelm), 1948- (Medpharm Publications, NISC (Pty) Ltd and Cogent, Taylor & Francis Group, 2015-01)
    The anti-inflammatory properties of statins are well documented. The aim of this study was to determine if statins may offer therapeutic benefits in rheumatoid arthritis (RA) patients that are also at risk for cardiovascular ...
  • Nell, Margo Judith; Wagener, Judith Marie; Zeevaart, Jan Rijn; Kilian, Elmare; Mamo, Messai Adenew; Layh, Marcus; Coyanis, M.; Jansen van Rensburg, Connie E. (Elsevier, 2009-07)
    The anti-tumour activity of the Au (I) phosphine complex [Au(dppe2]Cl was first discovered in the mid 1980s although promising results were obtained it did not pass clinical studies because of its toxicity to organs such ...
  • Steenkamp, Vanessa; Fernandes, Anthony C.; Jansen van Rensburg, Connie E. (Elsevier, 2007-12)
    Please refer to abstract in article
  • Koot, Dwayne Jonathan; Cromarty, Allan Duncan (Springer, 2015-06)
    Contemporary chemotherapy is limited by disseminated, resistant cancer. Targeting nanoparticulate drug delivery systems that encapsulate synergistic drug combinations are a rational means to increase the therapeutic ...
  • Outhoff, Kim (OpenJournals, 2009-07)
    Depression and sexual dysfunction are both common in the general population. When they co-exist they have the potential to impact negatively on each other in a bidirectional manner. Medication used to treat depression may ...
  • Adewusi, Emmanuel Adekanmi; Moodley, N.; Steenkamp, Vanessa (Elsevier, 2011)
    Alzheimer's disease (AD) is the most common type of dementia in the aging population. Enhancement of acetylcholine levels in the brain is one means of treating the disease. However, the drugs presently used in the management ...