AIM : The study aims to prepare a class of oleanolic-based compounds.
BACKGROUND : Conventional drugs used to treat infectious diseases suffer from limitations such as drug toxicity and drug resistance. The resistance ...
INTRODUCTION : A scarcity of local published data on colorectal cancer (CRC) postoperative complications, including postoperative ileus (POI), exists. POI is a temporary gastrointestinal (GI) state of absent or reduced ...
Mokwele, R. Nelly; Schellack, Natalie; Bronkhorst, Elmien; Brink, Adrian J.; Schweickerdt, Louise; Godman, Brian(Oxford University Press, 2022-03)
BACKGROUND : Inappropriate use of antimicrobials is a key factor increasing antimicrobial resistance, a major global public health problem including in South Africa. Key drivers include antibiotics being dispensed without ...
Wang, De Yun; Eccles, Ronald; Bell, John; Chua, Antonio Hao; Salvi, Sundeep; Schellack, Natalie; Marks, Paulette; Wong, Yong Chiat(Taylor and Francis, 2021)
INTRODUCTION : Upper respiratory tract infection (URTI) is an illness caused by an acute infection by viruses or bacteria of the nose, sinuses, pharynx, and larynx. Most URTIs are short, mild, and self-limiting, but some ...
De Beer, Rene; Outhoff, Kim; Phulukdaree, Alisa; Soma, Prashilla(Taylor and Francis, 2021)
Statins, the standard treatment for hypercholesterolaemia, among the most widely prescribed, have been associated with side effects, including statin intolerance. The aim of this study was to determine the background ...
Antimicrobial resistance (AMR) is a growing problem worldwide, including South Africa, where an AMR National Strategy Framework was implemented to instigate antimicrobial stewardship programmes (ASPs) and improve antimicrobial ...
Cordier, Werner; Nyoni, Champion N.(Health and Medical Publishing Group, 2021-09)
The COVID-19 pandemic reaffirms the need for the professionalisation of health professions education. The current higher education landscape in Africa privileges clinical competence over educational proficiency for educators ...
Cordier, Werner; Lubbe, J.C. (Irene)(Health and Medical Publishing Group, 2021-09)
The COVID-19 pandemic placed educators in unique circumstances, not
only due to their discipline- and student-specific considerations, but also
their personal and professional milieu. Given a series of sudden ...
Mlambo, Shamiso Shelter(Health & Medical Publishing Group, 2021-09)
It is not a debatable issue that the COVID‑19 pandemic created several challenges in the education sector, and institutions across the world had to employ various interventions to ensure continuation of teaching and learning. ...
Parkar, Hafiza(Health and Medical Publishing Group, 2021-10)
The pharmacology of antibacterials can be a tricky topic to lecture to students at any level. The cohort that we have is comprised of first-year medical students in their second semester, and teaching antibacterials at ...
Sakr, Samar; Steenkamp, Vanessa(Taylor and Francis, 2021)
Zinc oxide nanoparticles are incorporated into cosmetics and sunscreens and are widely used in biomedical applications and the food industry. The increasing use of zinc oxide nanoparticles raises concerns about their safety. ...
BACKGROUND : Toxicity data regarding combinational exposure of humans to arsenic, cadmium and mercury is scarce. Although hepatotoxicity has been reported, limited information is available on their mechanistic underpinnings. ...
The inaugural issue of The South African General Practitioner
(SAGP) is published in an unprecedented time of uncertainty,
fear and a 21-day nationwide lockdown. The country is rallying
to limit the spread of the spiky, ...
The management of anaemia in chronic kidney disease (CKD) patients is a complex, multifaceted process reliant on the administration of exogenous erythropoiesis stimulating agents (ESAs) and iron supplements to ensure the ...
Outhoff, Kim(Medpharm Publications, NISC (Pty) Ltd and Cogent, Taylor and Francis Group, 2017)
Children younger than 7 years are at increased risk of otitis media because of their immature immune systems and poorly functioning eustachian tubes that normally ventilate the middle ear space and equalize pressure with ...
Our lives changed dramatically eight months ago when we went into a hard nationwide lockdown in a bid to limit the transmission of our new spiky foe, SARS-CoV-2. We endured the uncertainties of autumn, and then the winter ...
Ker, James A.; Outhoff, Kim(Medpharm Publications, 2020-07)
Heart failure is a heterogeneous progressive syndrome of symptoms and signs, a culmination of structural and/or functional abnormalities of the heart. There is an elevated intracardiac pressure or reduced cardiac output ...
COVID-19 patients may face a long and winding road to recovery. Outcomes of critically ill patients have been well described, including in China, Italy and the USA, and particularly in the comorbid elderly. However, short-, ...
“The heart's memory eliminates the bad and magnifies the good,
and thanks to this artifice, we manage to endure the burden
of the past.” Gabriel García Márquez, 1985, Love in the Time of
Cholera.
Parkar, Hafiza; Cromarty, Allan Duncan(Medpharm Publications, 2020-11)
Healthcare professionals in general practice are tasked with treatment and management of wounds on a daily basis. The prognoses
of these wounds are directly affected by the ability of the clinician to assess these wounds ...