Browsing Research Articles (Immunology) by Subject "Reactive oxygen species"

Browsing Research Articles (Immunology) by Subject "Reactive oxygen species"

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  • Cigarette smoke condensate attenuates phorbol ester-mediated neutrophil extracellular trap formation 
    Bokaba, Refilwe Philadelphia; Anderson, Ronald; Theron, Annette J.; Tintinger, Gregory Ronald (Makerere University Medical School, 2017-09)
    BACKGROUND : Neutrophil extracellular traps (NETs) constitute a network of chromatin fibres containing histone and antimicrobial peptides that are released by activated neutrophils. NETs protect the host against infection ...
  • Clofazimine : current status and future prospects 
    Cholo, Moloko C.; Steel, Helen C.; Fourie, P.B. (Petrus Bernardus); Germishuizen, Willem Andreas; Anderson, Ronald (Oxford University Press, 2012-02)
    Clofazimine, a lipophilic riminophenazine antibiotic, possesses both antimycobacterial and anti-inflammatory activities. However, its efficacy has been demonstrated only in the treatment of leprosy, not in human tuberculosis, ...
  • Effects of moxifloxacin on human neutraphil and T-lymphocyte functions in vitro 
    Potjo, Moliehi; Cockeran, Riana; Theron, Annette J.; Feldman, Charles; Anderson, Ronald (Molecular Diversity Preservation International, 2010)
    Moxifloxacin is useful in the treatment of respiratory infections, including community-acquired pneumonia, and also shows promise in the treatment of tuberculosis, a clinical setting which necessitates extended administration ...
  • Harmful interactions of non-essential heavy metals with cells of the innate immune system 
    Theron, Annette J.; Tintinger, Gregory Ronald; Anderson, Ronald (2012-04-16)
    In trace amounts, some heavy metals are essential for optimum health, while exposure to others, which are non-essential, presents the potential hazard of acute or chronic organ toxicity. Cadmium, mercury, lead, ...
  • Inflammation and cancer : the role of the human neutrophil 
    Anderson, Ronald; Tintinger, Gregory Ronald; Feldman, Charles (AOSIS Open Journals, 2014-01)
    Chronic inflammation of both infective and non-infective origin has been implicated in the aetiology of approximately 30% of all human epithelial malignancies. The primary carcinogens are reactive oxygen species (ROS) ...
  • Reactive oxygen species and NOX enzymes are emerging as key players in cutaneous wound repair 
    Andre-Levigne, Dominik; Modarressi, Ali; Pepper, Michael Sean; Pittet-Cuenod, Brigitte (MDPI Publishing, 2017-10-15)
    Our understanding of the role of oxygen in cell physiology has evolved from its longrecognized importance as an essential factor in oxidative metabolism to its recognition as an important player in cell signaling. With ...
  • The role of reactive oxygen species in adipogenic differentiation 
    De Villiers, Danielle; Potgieter, Marnie; Ambele, Melvin Anyasi; Adam, Ladislaus; Durandt, Chrisna; Pepper, Michael Sean (Springer, 2017-11)
    Interest in reactive oxygen species and adipocyte differentiation/adipose tissue function is steadily increasing. This is due in part to a search for alternative avenues for combating obesity, which results from the excess ...
  • Role of the neutrophil in the pathogenesis of advanced cancer and impaired responsiveness to therapy 
    Rapoport, Bernardo Leon; Steel, Helen C.; Theron, Annette J.; Smit, Teresa; Anderson, Ronald (MDPI Publishing, 2020-04-01)
    Notwithstanding the well-recognized involvement of chronic neutrophilic inflammation in the initiation phase of many types of epithelial cancers, a growing body of evidence has also implicated these cells in the pathogenesis ...