Our understanding of the role of oxygen in cell physiology has evolved from its longrecognized
importance as an essential factor in oxidative metabolism to its recognition as an
important player in cell signaling. With regard to the latter, oxygen is needed for the generation of
reactive oxygen species (ROS), which regulate a number of different cellular functions including
differentiation, proliferation, apoptosis, migration, and contraction. Data specifically concerning the
role of ROS-dependent signaling in cutaneous wound repair are very limited, especially regarding
wound contraction. In this review we provide an overview of the current literature on the role of
molecular and reactive oxygen in the physiology of wound repair as well as in the pathophysiology
and therapy of chronic wounds, especially under ischemic and hyperglycemic conditions.
Silk has been used in textile production for centuries and in medicine, as sutures for decades. Sericin and fibroin are the two primary silk proteins. Silk has been shown to improve wound healing. Copper ions have also ...
The inhibition of reactive oxygen species (ROS) and the migration of fibroblasts are key processes involved in wound healing. In this study, the ability of aqueous ethnomedicinal plant extracts prepared from Aspilia africana ...
Bronkhorst, Petro Du Toit(University of Pretoria, 2014)
Wound healing is one of the most complex processes in the human body consisting of several
different phases namely inflammatory phase, proliferative phase, remodeling phase and contraction
phase (Jurjus et al., 2007). ...