Our understanding of the role of oxygen in cell physiology has evolved from its longrecognized
importance as an essential factor in oxidative metabolism to its recognition as an
important player in cell signaling. With regard to the latter, oxygen is needed for the generation of
reactive oxygen species (ROS), which regulate a number of different cellular functions including
differentiation, proliferation, apoptosis, migration, and contraction. Data specifically concerning the
role of ROS-dependent signaling in cutaneous wound repair are very limited, especially regarding
wound contraction. In this review we provide an overview of the current literature on the role of
molecular and reactive oxygen in the physiology of wound repair as well as in the pathophysiology
and therapy of chronic wounds, especially under ischemic and hyperglycemic conditions.
Silk has been used in textile production for centuries and in medicine, as sutures for decades. Sericin and fibroin are the two primary silk proteins. Silk has been shown to improve wound healing. Copper ions have also ...
Kruger, Johann; Katerere, David; Eloff, Jacobus Nicolaas(AOSIS Open Journals, 2018)
Plants are well-known sources of compounds with biological activity and thus have been
used by mankind for centuries as medicines. Terminalia sericea occurs widely in southern
Africa in sandy soils. It has been used ...
Meier, Jack; Owen, Laura; Wager, Catherine J.; International Veterinary Simulation in Teaching Conference (5th : 2017 : Pretoria, South Africa); University of Cambridge. Dept. of Veterinary Medicine(Pretoria : University of Pretoria, Faculty of Veterinary Science, 2017)
Teaching and learning of small animal wound management at the University of Cambridge is currently via the traditional lecture system. Recent graduates and current clinical students were surveyed in order to evaluate the ...