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Browsing Research Articles (Medical Microbiology) by UP Author "Omar, Shaheed Vally"
Now showing items 1-16 of 16
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Omar, Shaheed Vally; Roth, Andreas; Ismail, Nazir Ahmed; Erasmus, Linda; Ehlers, Marthie Magdaleen; Kock, Marleen M.; Paulse, Nuraan; Said, H.M. (Halima Mohammed); Hoosen, Anwar Ahmed; Reischl, Udo (Public Library of Science, 2011-09-22)BACKGROUND: The LightCyclerH Mycobacterium Detection Kit based on real-time PCR technology for the detection of Mycobacterium tuberculosis, Mycobacterium avium and Mycobacterium kansasii was recently developed. This study ...
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Said, Halima Mohammed; Kock, Marleen M.; Ismail, Nazir Ahmed; Baba, Kamaldeen A.; Omar, Shaheed Vally; Osman, Ayman Gassim Elamin; Hoosen, Anwar Ahmed; Ehlers, Marthie Magdaleen (BioMed Central, 2012-12-22)BACKGROUND: The increasing problem of multi-drug-resistant (MDR) tuberculosis (TB) [ie resistant to at least isoniazid (INH) and rifampicin (RIF)] is becoming a global problem. Successful treatment outcome for MDR-TB depends ...
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Strydom, Kathy-Anne; Ismail, Farzana; Matabane, M.M.Z.; Onwuegbuna, O.; Omar, Shaheed Vally; Ismail, Nabila (American Society for Microbiology, 2015-09)In a head to head comparison of the MTBDRplus Version 2.0 (Hain Lifescience), Xpert® MTB/RIF (Cepheid) and the Anyplex™ MTB/NTM (Seegene) assays we demonstrate equal sensitivity (59/61; 96.7%) and specificity (53/54; ...
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Said, Halima Mohammed; Kock, Marleen M.; Ismail, Nazir Ahmed; Baba, Kamaldeen A.; Omar, Shaheed Vally; Osman, Ayman Gassim Elamin; Hoosen, Anwar Ahmed; Ehlers, Marthie Magdaleen (International Union Against Tuberculosis and Lung Disease, 2012-01)BACKGROUND: The GenoType® MTBDRsl assay (Hains, Lifesciences, Germany) is a new rapid assay for detection of resistance to second-line anti-tuberculosis drugs. METHOD: The MTBDRsl assay was evaluated on 342 MDR-TB isolates ...
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Omar, Shaheed Vally; Peters, Remco P.H.; Ismail, Nazir Ahmed; Jonkman, Kelly; Dreyer, Andries W.; Said, Halima M.; Gwalab, Thabisile; Ismail, Nabila; Fourie, P.B. (Petrus Bernardus) (Wiley, 2016-06)Molecular tests are revolutionizing diagnosis of tuberculosis (TB). Disease burden is concentrated in resource-poor countries with inadequate infrastructure and capacity resulting in delays for specimens to reach the ...
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Omar, Shaheed Vally; Peters, Remco P.H.; Ismail, Nazir Ahmed; Dreyer, Andries W.; Said, Mohamed; Gwala, Thabisile; Ismail, Nabila; Fourie, P.B. (Petrus Bernardus) (Elsevier, 2015-10)BACKGROUND : Modern molecular-based approaches for the detection of Mycobacterium tuberculosis in sputum samples promise quicker and more accurate detection of cases. However, processing sputum samples at central diagnostic ...
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Said, Halima Mohammed; Kock, Marleen M.; Ismail, Nazir Ahmed; Mphahlele, Matsie Theodora; Baba, Kamaldeen A.; Omar, Shaheed Vally; Osman, Ayman Gassim Elamin; Hoosen, Anwar Ahmed; Ehlers, Marthie Magdaleen (American Society for Microbiology, 2012-09)Despite South Africa being one of the high-burden multidrug-resistant tuberculosis (MDR-TB) countries, information regarding the population structure of drug-resistant Mycobacterium tuberculosis strains is limited from ...
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Daum, Luke T.; Peters, Remco P.H.; Fourie, P.B. (Petrus Bernardus); Jonkman, K.; Worthy, Sue A.; Rodriguez, John D.; Ismail, Nazir Ahmed; Omar, Shaheed Vally; Fischer, Gerald W. (International Union Against Tuberculosis and Lung Disease, 2015-05)SETTING : Mopani District, South Africa. OBJECTIVE : To explore remote, molecular detection of Mycobacterium tuberculosis from sputum transported using PrimeStorew Molecular Transport Medium (PSMTM) compared to settings ...
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Daum, Luke T.; Rodriguez, John D.; Worthy, Sue A.; Ismail, Nazir Ahmed; Omar, Shaheed Vally; Dreyer, Andries W.; Fourie, P.B. (Petrus Bernardus); Hoosen, Anwar Ahmed; Chambers, James P.; Fischer, Gerald W. (American Society for Microbiology, 2012-12)A novel protocol for full-length Mycobacterium tuberculosis gene analysis of first- and second-line drug resistance was developed using the Ion Torrent Personal Genome Machine (PGM). Five genes—rpoB (rifampin), katG ...
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Daum, Luke T.; Fourie, P.B. (Petrus Bernardus); Bhattacharyya, Sanjib; Ismail, Nazir Ahmed; Gradus, Steve; Maningi, N.E. (Nontuthuko Excellent); Omar, Shaheed Vally; Fischer, Gerald W. (Oxford University Press, 2014-03-15)No abstract available.
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Ismail, Nazir Ahmed; Said, H.M. (Halima Mohammed); Pinini, Z.; Omar, Shaheed Vally; Beyers, N.; Naidoo, P. (Public Library of Science, 2015-11-06)INTRODUCTION Tuberculosis (TB) is a significant public health problem and the diagnosis in human immunodeficiency virus (HIV)—infected individuals is challenging. The use of mycobacterial culture remains an important ...
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Matabane, M.M.Z.; Ismail, Farzanah; Strydom, Kathy-Anne; Onwuegbuna, O.; Omar, Shaheed Vally; Ismail, Nabila (BioMed Central, 2015-11-09)BACKGROUND : A major challenge faced by countries with a high burden of tuberculosis (TB) is early detection especially in individuals with paucibacillary disease which is common in HIV endemic settings. Remarkable efforts ...
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Ismail, Nazir Ahmed; Omar, Shaheed Vally; Lewis, James J.; Dowdy, David W.; Dreyer, Andries W.; Van der Meulen, Hermina; Nconjana, George; Clark, David A.; Churchyard, Gavin J. (American Thoracic Society, 2015-06)RATIONALE : TBDx automated microscopy is a novel technology that processes digital microscopic images to identify acid-fast bacilli (AFB). Use of TBDx as part of a diagnostic algorithm could improve the diagnosis of ...
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Ehlers, Marthie Magdaleen; Hoosen, Anwar Ahmed; Omar, Shaheed Vally; Maningi, Nontuthuko Excellent; Makgothlo, E.; Kock, Marleen M.; Creative Studios, Dept of Education Innovation, University of Pretoria (2008-12-09)Extended-spectrum-beta-lactamases (ESBL) have been recovered from medical centres in South Africa since the late 1980’s but little is known about the various types of ESBLs present and their prevalence. Metallo-beta-lactamase ...
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Wake, Rachel M.; Govender, Nelesh; Omar, S.V. (Shaheed Vally); Ismail, Farzanah; Tiemessen, Caroline T.; Harrison, Thomas S.; Jarvis, Joseph N. (Lippincott, Williams & Wilkins, 2022-05)OBJECTIVE : Investigation of the diagnostic yield of urine-based tuberculosis (TB) screening in patients with advanced HIV disease. DESIGN : A cross-sectional screening study SETTING : HIV outpatient clinics and wards ...
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Ismail, Nazir Ahmed; Omar, Shaheed Vally; Walker, Timothy M.; Kohl, Thomas A.; Hedge, Jessica; Elias, Carlos Del Ojo; Bradley, Phelim; Iqbal, Zamin; Feuerriegel, Silke; Niehaus, Katherine E.; Wilson, Daniel J.; Clifton, David A.; Kapatai, Georgia; Ip, Camilla L.C.; Bowden, Rory; Drobniewski, Francis A.; Allix-Béguec, Caroline; Gaudin, Cyril; Parkhill, Julian; Diel, Roland; Supply, Philip; Crook, Derrick W.; Smith, E. Grace; Walker, A. Sarah; Niemann, Stefan; Peto, Tim E. A.; Davies, J.; Crichton, C.; Acharya, M.; Madrid-Marquez, Eyre, D.; Wyllie, D.; Golubchik, T.; Munang, M. (Elsevier, 2015-10)BACKGROUND : Diagnosing drug-resistance remains an obstacle to the elimination of tuberculosis. Phenotypic drugsusceptibility testing is slow and expensive, and commercial genotypic assays screen only common resistanced ...
Now showing items 1-16 of 16