In a head to head comparison of the MTBDRplus Version 2.0 (Hain Lifescience), Xpert®
MTB/RIF (Cepheid) and the Anyplex™ MTB/NTM (Seegene) assays we demonstrate equal
sensitivity (59/61; 96.7%) and specificity (53/54; 98.1%) for detecting rifampicin resistance
with further analysis of discordances. The Xpert does not detect Isoniazid resistance while
Anyplex showed high false positivity.