Sepsis and septic shock are key contributors to mortality in critically ill patients and thus
prompt recognition and management thereof is central to achieving improved patient outcomes. Early initiation of appropriate ...
Takawira, Faustinos Tatenda; Pitout, Johann D.D.; Thilliez, Gaetan; Mashe, Tapfumanei; Gutierrez, Ana Victoria; Kingsley, Robert A.; Peirano, Gisele; Matheu, Jorge; Midzi, Stanley M.; Mwamakamba, Lusubilo W.; Gally, David L.; Tarupiwa, Andrew; Mukavhi, Leckson; Ehlers, Marthie Magdaleen; Mtapuri-Zinyowera, Sekesai; Kock, Marleen M.(Springer, 2022)
This study was designed to characterize extended-spectrum beta-lactamase (ESBL)–producing extra-intestinal pathogenic Escherichia coli (E.coli) (ExPEC) associated with urinary tract infections in nine different geographic ...
De Jesus, Marissa Batista(University of Pretoria, 2015)
Genetic typing of Klebsiella pneumoniae is used for epidemiological referencing. In the clinical setting it can be useful in outbreak investigations, understanding transmission and managing hospital infections. Multi-drug ...
Beksinska, Mags; Issema, Rodal; Beesham, Ivana; Lalbahadur, Tharnija; Thomas, Katherine; Morrison, Charles; Hofmeyr, G. Justus; Steyn, Petrus S.; Mugo, Nelly; Palanee-Phillips, Thesla; Ahmed, Khatija; Nair, Gonasagrie; Baeten, Jared M.; Smit, Jenni(Elsevier, 2021-04)
BACKGROUND : There is limited evidence on the impact of the use of progestin-only hormonal contraception
(POC) on weight change. We conducted a secondary analysis of prospective weight change among women
enrolled in the ...
BACKGROUND : Targeted metagenomics and IS-Pro method are two of the many methods that have been used to
study the microbiome. The two methods target different regions of the 16 S rRNA gene. The aim of this study was
to ...
BACKGROUND : The vaginal microbiota (VMB) are the set of microorganisms residing in the human vagina. During
pregnancy, their composition is Lactobacillus-dominant in most Caucasian women. Previous studies suggest that
the ...
Peirano, Gisele; Chen, Liang; Kreiswirth, Barry N.; Pitout, Johann D.D.(American Society for Microbiology, 2020-09)
There is an enormous global public health burden due to antimicrobial-resistant (AMR) Klebsiella pneumoniae high-risk clones. K. pneumoniae ST307 and ST147 are recent additions to the family of successful clones in the ...
Medina-Marino, Andrew; Mudau, Maanda; Kojima, Noah; Peters, Remco P.H.; Feucht, Ute Dagmar; De Vos, Lindsey; Olivier, Dawie; Muzny, Christina A.; McIntyre, James A.; Klausner, Jeffrey D.(Sage, 2020-03)
The objective of this study is to assess the predictors and frequency of persistent sexually transmitted infection (STI) positivity in human immunodeficiency virus (HIV)-infected pregnant women treated for Chlamydia ...
Ongole, J.J.; Rossouw, Theresa M.; Fourie, P.B. (Petrus Bernardus); Stoltz, Anton Carel; Hugo, Johannes F.M.; Marcus, Tessa S.(International Union Against Tuberculosis and Lung Disease, 2020-06)
Fadal, Riyas; Wadee, Shoyab; Hoosen, Anwar Ahmed(Health and Medical Publishing Group, 2020-08)
The COVID-19 epidemic in South Africa (SA) is currently in a growth phase with high incidences in most major cities. Patients who are dependent on chronic renal dialysis care, including peritoneal dialysis and haemodialysis, ...
BACKGROUND: Studies have shown that drug-resistant tuberculosis (DR-TB) in South Africa (SA) is clonal and is
caused mostly by transmission. Identifying transmission chains is important in controlling DR-TB. This study ...
BACKGROUND: South Africa has unique and diverse social and economic factors that have an impact on the
provision of basic water, sanitation, hygiene and waste management infrastructure and practices at health care
facilities ...
BACKGROUND: Owing to antibiotic resistance, alternative antimicrobials from medicinal plants are receiving attention
as leads for anti-infective agents. This study aimed to investigate selected tree species and their ...
Current guidelines recommend starting antiretroviral therapy (ART) as soon as possible after HIV
diagnosis to reduce morbidity, mortality and onward HIV transmission. We examined factors
influencing ART initiation by ...
Nelson, Kristin N.; Gandhi, Neel R.; Mathema, Barun; Lopman, Benjamin A.; Brust, James C.M.; Auld, Sara C.; Ismail, Nazir Ahmed; Omar, Shaheed Vally; Brown, Tyler S.; Allana, Salim; Campbell, Angie; Moodley, Pravi; Mlisana, Koleka; Shah, N. Sarita; Jenness, Samuel M.(Oxford University Press, 2020-07)
Patterns of transmission of drug-resistant tuberculosis (TB) remain poorly understood, despite over half a million incident cases worldwide in 2017. Modeling TB transmission networks can provide insight into drivers of ...
Drug-resistant tuberculosis persists as a major public health concern. Alongside efficacious treatments, validated and standardized drug susceptibility testing (DST) is required to improve patient care. This multicountry, ...