Sebola, Dikeledi; Oguttu, James W.; Kock, Marleen M.; Qekwana, Daniel Nenene(Frontiers Media, 2023-01-09)
BACKGROUND : Hospital-acquired infections (HAIs) are associated with increased
mortality, morbidity, and an economic burden due to costs associated with
extended hospital stays. Furthermore, most pathogens associated ...
Mataseje, L.F.; Pitout, Johann D.D.; Croxen, M.; Mulvey, M.R.; Dingle, T.C.(Springer, 2023-10)
To investigate the acquisition and relatedness of New Delhi Metallo-beta-lactamase among multiple separate species from
one patient. Five isolates from three species (Pseudomonas aeruginosa; Pa, Acinetobacter baumannii; ...
COVID-19 vaccine efficacy (VE) has been observed to vary against antigenically distinct SARS-CoV-2 variants of concern (VoC). Here we report the final analysis of VE and safety from COV005: a phase 1b/2, multicenter, ...
Smith, Anthony M.; Sekwadi, Phuti; Erasmus, Linda K.; Lee, Christine C.; Stroika, Steven G.; Ndzabandzaba, Sinenhlanhla; Nel, Jeremy; Njamkepo, Elisabeth; Thomas, Juno; Weill, Francois-Xavier(Centers for Disease Control and Prevention, 2023-08)
Since February 2022, Malawi has experienced a cholera outbreak of >54,000 cases. We investigated 6 cases in South Africa and found that isolates linked to the outbreak were Vibrio cholerae O1 serotype Ogawa from seventh ...
Salvador-Oke, Kafilat Taiwo(University of Pretoria, 2023-11)
Antimicrobial resistance (AMR) due to Enterobacterales is a worldwide public health threat. The continuous emergence of multidrug resistant (MDR) bacteria in developing countries with poor sanitation programmes, inactive ...
Yacobson, Irina; Wanga, Valentine; Ahmed, Khatija; Chipato, Tsungai; Gichangi, Peter; Kiarie, James; Louw, Cheryl; Morrison, Susan; Moss, Margaret; Mugo, Nelly R.; Palanee-Phillips, Thesla; Pleaner, Melanie; Scoville, Caitlin W.; Thomas, Katherine K.; Nanda, Kavita; for the Evidence for Contraceptive Options and HIV Outcomes (ECHO) Trial Consortium(Elsevier, 2023)
OBJECTIVES : To assess the rates of failed insertion, expulsion, and perforation when intrauterine device
(IUD) insertions were done by newly trained clinicians, and to examine factors that may affect these
outcomes.
STUDY ...
Peirano, G.; Castellanos, L. Ricardo; Matsumura, Yasufumi; Chaffee, Ryan; Castaneda-Mogollon, Daniel; Pillai, Dylan R.; Pitout, Johann D.D.(American Society for Microbiology, 2024-03)
The dissemination of Escherichia coli multidrug-resistant (MDR) STc131 is related to its persistence in the human gastrointestinal tract as efficient gut colonizers. Infection and prevention measures are the cornerstones ...
Bonner, Courtney Peasant; Minnis, Alexandra M.; Ndirangu, Jacqueline W.; Browne, Felicia A.; Speizer, Ilene; Nyblade, Laura; Ahmed, Khatija; Wechsberg, Wendee M.(Springer, 2023-12)
Adolescent girls and young women (AGYW) account for 25% of new HIV infections in South Africa. Pre-exposure prophylaxis (PrEP) is approved by the South African Government, but the factors that promote PrEP uptake among ...
Browne, Erica N.; Manenzhe, Kgahlisho; Makoni, Wanzirai; Nkomo, Sikhanyisiwe; Mahaka, Imelda; Ahmed, Khatija; Shapley‑Quinn, Mary Kate; Marton, Tozoe; Luecke, Ellen; Johnson, Leah; Van der Straten, Ariane; Minnis, Alexandra M.(BMC, 2023-02-10)
BACKGROUND : Input from end-users during preclinical phases can support market fit for new HIV prevention technologies.
With several long-acting pre-exposure prophylaxis (PrEP) implants in development, we aimed to ...
Gigi, Ranjana M. S.; Buitrago‑Garcia, Diana; Taghavi, Katayoun; Dunaiski, Cara‑Mia; Van de Wijgert, Janneke H.H.M.; Peters, Remco P.H.; Low, Nicola(BMC, 2023-03-21)
BACKGROUND : Vulvovaginal yeast infections in pregnancy are common and can cause extensive inflammation, which
could contribute to adverse pregnancy outcomes. Symptomatic yeast infections are likely to cause more ...
Gigi, Ranjana M. S.; Mdingi, Mandisa M.; Jung, Hyunsul; Claassen-Weitz, Shantelle; Butikofer, Lukas; Klausner, Jeffrey D; Muzny, Christina A.; Taylor, Christopher M.; Van de Wijgert, Janneke H.H.M.; Peters, Remco P.H.; Low, Nicola(BMJ Publishing Group, 2023-12)
INTRODUCTION : Preterm birth complications are the most
common cause of death in children under 5 years.
The presence of multiple microorganisms and genital
tract inflammation could be the common mechanism
driving early ...
Myataza, Asive; Thomas, Juno; Smith, Anthony M.(BMC, 2023-11)
BACKGROUND : We describe the genotypic characteristics and antimicrobial resistance (AMR) determinants of Salmonella
enterica serovar Isangi (Salmonella Isangi) clinical isolates in South Africa from 2020 through ...
BACKGROUND : The tuberculosis (TB) epidemic remains a major global health problem and Eswatini is not excluded.
Our study investigated the circulating genotypes in Eswatini and compared them at baseline (start of ...
Ogundare, Samuel Tolulope(University of Pretoria, 2023-12)
Globally, antimicrobial resistance (AMR) in foodborne pathogenic bacteria of the family Enterobacteriaceae has continued to rise. There is an increase in public health concerns about the spread of multi-drug resistant (MDR) ...
Madhi, Shabir A.; Anderson, Annaliesa S.; Absalon, Judith; Radley, David; Simon, Raphael; Jongihlati, Babalwa; Strehlau, Renate; Van Niekerk, Anika M.; Izu, Alane; Naidoo, Niree; Kwatra, Gaurav; Ramsamy, Yogandree; Said, Mohamed; Jones, Stephanie; Jose, Lisa; Fairlie, Lee; Barnabas, Shaun L.; Newton, Ryan; Munson, Samantha; Jefferies, Zahra; Pavliakova, Danka; Silmon de Monerri, Natalie C.; Gomme, Emily; Perez, John L.; Scott, Daniel A.; Gruber, William C.; Jansen, Kathrin U.(Massachusetts Medical Society, 2023-07)
BACKGROUND : Natural history studies have correlated serotype-specific anti–capsular polysaccharide (CPS) IgG in newborns with a reduced risk of group B streptococcal disease. A hexavalent CPS–cross-reactive material 197 ...
Fry, Samantha; Chokephaibulkit, Kulkanya; Pallem, Sridevi; Henry, Ouzama; Pu, Yongjia; Akawung, Agnes; Kim, Joon Hyung; Yanni, Emad; Tullio, Antonella Nadia; Aurpibul, Linda; Lee, Christine Mui Fong; Ceballos, Ana; Zaman, Khalequ; Abadia de Regalado, Ivonne; Ahmed, Khatija; Arias Fernandez, Diana Andrea; Taher, Sri Wahyu; Caccavo, Juliana; Coutinho, Conrado Milani; D'Andrea Nores, Ulises; De Leon, Tirza; D'Silva, Emily Christine; De Bernardi, Mara; Dieser, Pablo; Falaschi, Andrea; Flores Acosta, Clara del Carmen; Gentile, Angela; Teo, Ik Hui; Kotze, Sheena; Lopez-Medina, Eduardo; Luca, Ruben; Lucion, Maria Florencia; Mantaring, Jacinto Blas V., III; Marin, Bladimir; Moelo, Malahleha; Mussi-Pinhata, Marisa Marcia; Pinto, Jorge; Puthanakit, Thanyawee; Reyes, Osvaldo; Roa, Maria Fernanda; Rodriguez Brieschke, Maria Teresa; Rodriguez, Camilo Enrique; Rodriguez Nino, Juan Nicolas; Schwarzbold, Alexandre Vargas; Sierra Garcia, Alexandra; Sivapatham, Lavitha; Soon, Ruey; Tinoco, Juan Carlos; Velasquez Penagos, Jesus Arnulfo; Dos Santos, Gael(Oxford University Press, 2023-12)
BACKGROUND : Incidence data of respiratory syncytial virus–associated lower respiratory tract illness (RSV-LRTI) are sparse in low- and middle-income countries (LMICs). We estimated RSV-LRTI incidence rates (IRs) in infants ...