Browsing Medical Microbiology by Issue Date

Browsing Medical Microbiology by Issue Date

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  • Part VII : Interventions 
    Visser, Adele; Moore, D.P.; Whitelaw, Andrew; Lowman, W.; Kantor, G.; Hoosen, Anwar Ahmed; Madhi, Shabir A.; Brink, A.; Van den Bergh, D.; Devenish, L.; Moodley, P.; Apalata, T.; Duse, A.G.; Gelband, H. (Health and Medical Publishing Group, 2011-08)
    Antimicrobial resistance (AMR) surveillance activities in South Africa have been described in Part V of this report. Surveillance – knowing the levels of resistance and the trends around the country and in different ...
  • Part V. Surveillance activities 
    Bamford, C.; Brink, A.; Govender, N.; Lewis, D.A.; Perovic, Olga; Botha, M.; Harris, B.; Keddy, Karen H.; Gelband, H.; Duse, A.G. (Health and Medical Publishing Group, 2011-08)
    The critical importance of robust antimicrobial resistance (AMR) surveillance in South Africa cannot be overemphasised. Without knowing what the resistance situation is, it is impossible to develop appropriate antibiotic ...
  • Analytical performance of the Roche Lightcycler® Mycobacterium Detection Kit for the diagnosis of clinically important mycobacterial species 
    Omar, Shaheed Vally; Roth, Andreas; Ismail, Nazir Ahmed; Erasmus, Linda; Ehlers, Marthie Magdaleen; Kock, Marleen M.; Paulse, Nuraan; Said, H.M. (Halima Mohammed); Hoosen, Anwar Ahmed; Reischl, Udo (Public Library of Science, 2011-09-22)
    BACKGROUND: The LightCyclerH Mycobacterium Detection Kit based on real-time PCR technology for the detection of Mycobacterium tuberculosis, Mycobacterium avium and Mycobacterium kansasii was recently developed. This study ...
  • Meningococcal infections in hospitalised patients in Pretoria 
    Moodley, Teshni; Lekalakala, M. Ruth; De Gouveia, L.; Dangor, Yusuf; Hoosen, Anwar Ahmed (Health and Medical Publishing Group, 2011-10)
    We report on 13 patients diagnosed with meningococcal infections in patients attending state-owned hospitals serving an indigent population in Pretoria in 2009. The case fatality rate was 27%. Ceftriaxone was the main ...
  • Serotype and antimicrobial profile distribution of invasive pneumococcal isolates in the pre-vaccine introduction era in Pretoria, South Africa, 2005 through 2009 
    Ismail, Nazir Ahmed; Hoosen, Anwar Ahmed; Silberbauer, Eduard Johan; Von Gottberg, Anne (Elsevier, 2011-11)
    A description of invasive Streptococcus pneumoniae isolates over a 5-year period from blood culture and cerebrospinal fluid culture follows, in Pretoria South Africa January 2005 through December 2009. Isolates were ...
  • Prevalence of Clostridium difficile toxin genes in Pretoria 
    Storm, Nadia; Kock, Marleen M.; Kruger, M.D.; Ehlers, Marthie Magdaleen (Federation of Infectious Diseases Societies of South Africa, 2012)
    The hypervirulent polymerase chain reaction (PCR) ribotype 027 strain of Clostridium difficile produces toxins A, B and a binary toxin. Toxin detection kits are commonly used in diagnostic laboratories, but have been ...
  • Biting off more than you can chew : microbiological flora isolated from human and animal bite wounds 
    Visser, Adele; Visser, Hilgaard Frans (Media 24 & South African Orthopaedic Association, 2012)
    BACKGROUND: Bite wounds, from human and animal origin, can lead to significant complications if appropriate therapy is not undertaken timeously. A basic knowledge of the microbiological flora is essential for each clinical ...
  • Clinical trials of TB vaccines : harmonization and cooperation 
    Mahomed, Hassan; Fourie, P.B. (Petrus Bernardus) (Elsevier, 2012)
    A new efficacious tuberculosis (TB) vaccine has the potential to dramatically assist control efforts for the global TB epidemic. Good progress has been made with the clinical development of new TB vaccine candidates with ...
  • The Centre for Tuberculosis : from reference laboratory to public health institution 
    Ismail, Nazir Ahmed; Ihekweazu, Chikwe; Koornhof, Hendrik; Madhi, Shabir A. (Federation of Infectious Diseases Societies of South Africa, 2012)
    Tuberculosis (TB) continues to be one of the biggest public health challenges of our time, and as epidemiology of the disease evolves in an era of high HIV prevalence in South Africa, so must the response. With exciting ...
  • Human papillomavirus (HPV) vaccines 
    Visser, Adele; Hoosen, Anwar Ahmed (Health and Medical Publishing Group, 2012-01)
    Human papillomavirus (HPV) infection has been estimated to cause 270 000 deaths worldwide annually from cervical cancer and approximately 80% of these occur in resource-poor countries.1 In South Africa, cervical cancer ...
  • Evaluation of the GenoType (R) MTBDRsl assay for susceptibility testing of second-line anti-tuberculosis drugs 
    Said, Halima Mohammed; Kock, Marleen M.; Ismail, Nazir Ahmed; Baba, Kamaldeen A.; Omar, Shaheed Vally; Osman, Ayman Gassim Elamin; Hoosen, Anwar Ahmed; Ehlers, Marthie Magdaleen (International Union Against Tuberculosis and Lung Disease, 2012-01)
    BACKGROUND: The GenoType® MTBDRsl assay (Hains, Lifesciences, Germany) is a new rapid assay for detection of resistance to second-line anti-tuberculosis drugs. METHOD: The MTBDRsl assay was evaluated on 342 MDR-TB isolates ...
  • Causes of hyperferritinaemia classified by HIV status in a tertiary-care setting in South Africa 
    Visser, Adele; Mostert, Chris J. (Cambridge University Press, 2012-03)
    This study included all patients, with known HIV-1 status, admitted to hospital over a 5-year period with serum ferritin values exceeding 1500 mg/l. Markedly elevated serum ferritin levels are associated with a host of ...
  • In vitro activity of tigecycline against clinical isolates of carbapenem resistant Acinetobacter baumannii complex in Pretoria, South Africa 
    Ahmed, Nahid H.; Baba, Kamaldeen A.; Clay, Cornelius G.; Lekalakala, M. Ruth; Hoosen, Anwar Ahmed (BioMed Central, 2012-05-03)
    BACKGROUND: The presence of multi-drug resistant Acinetobacter baumannii raises a big therapeutic challenge in our hospital. Tigecycline, a new glycylcycline with expanded broad spectrum of activity against multi-drug ...
  • Systemic shigellosis in South Africa 
    Keddy, Karen H.; Sooka, Arvinda; Crowther-Gibson, Penny; Quan, Vanessa; Meiring, Susan; Cohen, Cheryl; Nana, Trusha; Sriruttan, Charlotte; Seetharam, Sharona; Hoosen, Anwar Ahmed; Naicker, Preneshni; Elliott, Eugenne; Haffejee, Summaya; Whitelaw, Andrew; Klugman, Keith P. (University of Chicago Press, 2012-05-15)
    BACKGROUND: Systemic disease due to shigellae is associated with human immunodeficiency virus (HIV), malnutrition, and other immunosuppressed states. We examined the clinical and microbiologic characteristics of systemic ...
  • Fresh-frozen plasma use in a South African tertiary hospital 
    Visser, Adele; Geldenhuys, Annelize; Du Preez, Samantha; Van de Vyver, Annemarie (Health and Medical Publishing Group, 2012-06)
    Despite available guidelines on indications for fresh-frozen plasma (FFP) transfusion, inappropriate use is increasing worldwide. We evaluated FFP administration to patients admitted to the Steve Biko Academic Hospital ...
  • Detection and characterisation of Ureaplasma spp in men with and without urogenital symptoms 
    Maningi, N.E. (Nontuthuko Excellent) (University of Pretoria, 2012-08-08)
    Ureaplasma spp colonize the lower genital tract in many healthy men, yet can also cause urethritis and infertility. Since Ureaplasma spp are frequently isolated from the normal urogenital tract, it has been suggested ...
  • Detection and characterization of ESBL positive Klebsiella pneumoniae clinical isolates 
    Manenzhe, Gumanzi Isaac (University of Pretoria, 2012-08-14)
    Klebsiella pneumoniae is an important nosocomial pathogen that has the potential to cause severe morbidity and mortality, particularly in intensive care units, as well as in medical and surgical wards. In recent years, ...
  • Molecular characterization and second-line antituberculosis drug resistance patterns of multidrug-resistant mycobacterium tuberculosis isolates from the Northern Region of South Africa 
    Said, Halima Mohammed; Kock, Marleen M.; Ismail, Nazir Ahmed; Mphahlele, Matsie Theodora; Baba, Kamaldeen A.; Omar, Shaheed Vally; Osman, Ayman Gassim Elamin; Hoosen, Anwar Ahmed; Ehlers, Marthie Magdaleen (American Society for Microbiology, 2012-09)
    Despite South Africa being one of the high-burden multidrug-resistant tuberculosis (MDR-TB) countries, information regarding the population structure of drug-resistant Mycobacterium tuberculosis strains is limited from ...
  • Combination vaccines in the South African setting 
    Visser, Adele; Hoosen, Anwar Ahmed (Elsevier, 2012-09-07)
    The number of vaccines available and included as part of the national immunization schedules, has increased significantly over the past few decades. This impacts on patient/parent compliance and creates a challenge for ...
  • Haemophilus influenzae type b conjugate vaccines : a South African perspective 
    Visser, Adele; Hoosen, Anwar Ahmed; Hussey, Greg (Elsevier, 2012-09-07)
    Introduction of Hib vaccine is known to positively impact on reduction of both morbidity and mortality in children less than 5 years of age. Incorporation of this vaccine into a National EPI, however, does come at a ...