Browsing Research Articles (Medical Virology) by Title

Browsing Research Articles (Medical Virology) by Title

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  • Genetic characterisation of South African and Mozambican bovine rotaviruses reveals a typical bovine-like artiodactyl constellation derived through multiple reassortment events 
    Strydom, Amy; Donato, Celeste M.; Nyaga, Martin M.; Boene, Simone S.; Peenze, Ina; Mogotsi, Milton T.; João, Eva D.; Munlela, Benilde; Potgieter, A. Christiaan; Seheri, Mapaseka L.; De Deus, Nilsa; O’Neill, Hester G. (MDPI, 2021-10-12)
    This study presents whole genomes of seven bovine rotavirus strains from South Africa and Mozambique. Double-stranded RNA, extracted from stool samples without prior adaptation to cell culture, was used to synthesise ...
  • Genetic determinants of virulence in pathogenic lineage 2 West Nile virus strains 
    Botha, Elizabeth Magdelena; Markotter, Wanda; Wolfaardt, Marianne; Paweska, Janusz Tadeusz; Swanepoel, Robert; Palacios, Gustavo; Nel, Louis Hendrik; Venter, Marietjie (Coordinating Center for Infectious Diseases, Centers for Disease Control and Prevention, 2008-02)
    We determined complete genome sequences of lineage 2 West Nile virus (WNV) strains isolated from patients in South Africa who had mild or severe WNV infections. These strains had previously been shown to produce either ...
  • Genetic diversity and molecular epidemiology of human rhinoviruses in South Africa 
    Pretorius, Marthi Andréa; Tempia, Stefano; Treurnicht, Florette K.; Walaza, Sibongile; Cohen, Adam L.; Moyes, Jocelyn; Hellferscee, Orienka; Variava, Ebrahim; Dawood, Halima; Chhagan, Meera; Haffejee, Summaya; Madhi, Shabir A.; Cohen, Cheryl; Venter, Marietjie (Wiley, 2014-07-03)
    BACKGROUND Rhinoviruses (RV) are a well-established cause of respiratory illness. RV-C has been associated with more severe illness. We aimed to characterize and compare the clinical presentations and disease severity ...
  • Genetic diversity of Culex pipiens mosquitoes in distinct populations from Europe : contribution of Cx. quinquefasciatus in Mediterranean populations 
    Shaikevich, Elena V.; Vinogradova, Elena B.; Bouattour, Ali; De Almeida, Antonio Paulo Gouveia (BioMed Central, 2016-01-27)
    BACKGROUND : Mosquitoes of the Culex pipiens complex are cosmopolitan, and important vectors of neglected tropical diseases, such as arbovirosis and lymphatic filariasis. Among the complex taxa, Cx. pipiens (with two ...
  • Genome sequence analysis of in vitro and in vivo phenotypes of Bunyamwera and Ngari virus isolates from Northern Kenya 
    Odhiambo, Collins; Venter, Marietjie; Limbaso, Konongoi; Swanepoel, Robert; Sang, Rosemary; Aguilar, Patricia V. (Public Library of Science, 2014-08-25)
    Biological phenotypes of tri-segmented arboviruses display characteristics that map to mutation/s in the S, M or L segments of the genome. Plaque variants have been characterized for other viruses displaying varied ...
  • Genomic and phylogenetic characterization of Shuni virus 
    Van Eeden, Charmaine; Harders, Frank; Kortekaas, Jeroen; Bossers, Alex; Venter, Marietjie (Springer, 2014-06)
    Shuni virus (SHUV), a member of the genus Orthobunyavirus, has in a recent study been associated with neurological disease in horses in South Africa. After its first isolation in 1966 from an asymptomatic bovine, very ...
  • The geographic distribution of priority population groups for the elimination of mother-to-child transmission of HIV in South Africa 
    Moyo, Faith; Mazanderani, Ahmad Haeri; Kufa, Tendesayi; Sherman, Gayle G. (Public Library of Science, 2020-04-08)
    BACKGROUND Women of reproductive age living with HIV (WRLHIV), HIV-positive pregnant women, adolescent girls and young women (AGYW) are key populations for eliminating mother-to-child of HIV (eMTCT) in South Africa. We ...
  • Global distribution of novel rhinovirus genotype 
    Briese, Thomas; Renwick, Neil; Venter, Marietjie; Jarman, Richard G.; Ghosh, Dhrubaa; Kondgen, Sophie; Shrestha, Sanjaya K.; Hoegh, A. Mette; Casas, Inmaculada; Adjogoua, Edgard Valerie; Akoua-Koffi, Chantal; Myint, Khin Saw; Williams, David T.; Chidlow, Glenys; Van den Berg, Ria; Calvo, Cristina; Koch, Orienka; Palacios, Gustavo; Kapoor, Vishal; Villari, Joseph; Dominguez, Samuel R.; Holmes, Kathryn V.; Harnett, Gerry; Smith, David; Mackenzie, John S.; Ellerbrok, Heinz; Schweiger, Brunhilde; Schonning, Kristian; Chadha, Mandeep S.; Leendertz, Fabian H.; Mishra, A.C.; Gibbons, Robert V.; Holmes, Edward C.; Lipkin, Ian W. (Coordinating Center for Infectious Diseases, Centers for Disease Control and Prevention, 2008-06)
    Global surveillance for a novel rhinovirus genotype indicated its association with community outbreaks and pediatric respiratory disease in Africa, Asia, Australia, Europe, and North America. Molecular dating indicates ...
  • Global role and burden of influenza in pediatric respiratory hospitalizations, 1982–2012 : a systematic analysis 
    Venter, Marietjie; Lafond, Kathryn E.; Nair, Harish; Rasooly, Mohammad Hafiz; Valente, Fatima; Guzman, Guiselle; Coulibaly, Daouda; Armero, Julio; Jima, Daddi; Howie, Stephen R. C.; Ampofo, William; Mena, Ricardo; Chadha, Mandeep; Sampurno, Ondri Dwi; Emukule, Gideon O.; Nurmatov, Zuridin; Corwin, Andrew; Heraud, Jean Michel; Noyola, Daniel E.; Cojocaru, Radu; Nymadawa, Pagbajabyn; Barakat, Amal; Adedeji, Adebayo; Von Horoch, Marta; Olveda, Remigio; Nyatanyi, Thierry; Mmbaga, Vida; Chittaganpitch, Malinee; Nguyen, Tran Hien; Theo, Andros; Whaley, Melissa; Azziz-Baumgartner, Eduardo; Bresee, Joseph; Campbell, Harry; Widdowson, Marc-Alain; Booy, Robert (Public Library of Science, 2016-03-24)
    BACKGROUND The global burden of pediatric severe respiratory illness is substantial, and influenza viruses contribute to this burden. Systematic surveillance and testing for influenza among hospitalized children has ...
  • Global spread of norovirus GII.17 Kawasaki 308, 2014–2016 
    Chan, Martin C.W.; Hu, Yunwen; Chen, Haili; Podkolzin, Alexander T.; Zaytseva, Ekaterina V.; Komano, Jun; Sakon, Naomi; Poovorawan, Yong; Vongpunsawad, Sompong; Thanusuwannasak, Thanundorn; Hewitt, Joanne; Croucher, Dawn; Collins, Nikail; Vinje, Jan; Pang, Xiaoli L.; Lee, Bonita E.; De Graaf, Miranda; Van Beek, Janko; Vennema, Harry; Koopmans, Marion P.G.; Niendorf, Sandra; Poljsak-Prijatelj, Mateja; Steyer, Andrej; White, Peter A.; Lun, Jennifer H.; Mans, Janet; Hung, Tin-Nok; Kwok, Kirsty; Cheung, Kelton; Lee, Nelson; Chan, Paul K.S. (Coordinating Center for Infectious Diseases, Centers for Disease Control and Prevention, 2017-08)
    Analysis of complete capsid sequences of the emerging norovirus GII.17 Kawasaki 308 from 13 countries demonstrated that they originated from a single haplotype since the initial emergence in China in late 2014. Global ...
  • Global trends in norovirus genotype distribution among children with acute gastroenteritis 
    Cannon, Jennifer L.; Bonifacio, Joseph; Bucardo, Filemon; Buesa, Javier; Bruggink, Leesa; Chan, Martin Chi-Wai; Fumian, Tulio M.; Giri, Sidhartha; Gonzalez, Mark D.; Hewitt, Joanne; Lin, Jih-Hui; Mans, Janet; Munoz, Christian; Pan, Chao-Yang; Pang, Xiao-Li; Pietsch, Corinna; Rahman, Mustafiz; Sakon, Naomi; Selvarangan, Rangaraj; Browne, Hannah; Barclay, Leslie; Vinje, Jan (Coordinating Center for Infectious Diseases, Centers for Disease Control and Prevention, 2021)
    Noroviruses are a leading cause of acute gastroenteritis (AGE) among adults and children worldwide. Noro- Surv is a global network for norovirus strain surveillance among children <5 years of age with AGE. Participants ...
  • Hand-foot-and-mouth disease caused by coxsackievirus A6 in a patient infected with HIV 
    Mayaphi, Simnikiwe Horatious; Van Zyl, Walda B.; Sono, Tinah; Loots, Donovan P.; Taylor, Maureen B. (MedPharm Publications, 2015)
    Hand, foot and mouth disease (HFMD) is common in children ≤ 5 years of age, and is mainly caused by enterovirus 71 and coxsackievirus A16 (CVA6). A 12-year-old boy on treatment for human immunodeficiency virus (HIV) ...
  • HBV/HIV co-infection : the dynamics of HBV in South African patients with AIDS 
    Mayaphi, Simnikiwe Horatious; Rossouw, Theresa M.; Masemola, Difuro P.; Olorunju, Steve A.S.; Mphahlele, M. Jeffrey; Martin, Desmond J. (Health and Medical Publishing Group, 2012-03)
    OBJECTIVE: As sub-Saharan Africa is highly endemic for hepatitis B virus (HBV) and human immunodeficiency virus (HIV) infections, and their co-infection requires special management, we aimed to assess the serological and ...
  • Hepatitis A virus seroprevalence in South Africa - estimates using routine laboratory data, 2005–2015 
    Mazanderani, Ahmad Haeri; Motaze, Nkengafac Villyen; McCarthy, Kerrigan; Suchard, Melinda; Du Plessis, Nicolette Marie (Public Library of Science, 2019-06)
    INTRODUCTION : South Africa is considered highly endemic for hepatitis A virus (HAV) although few seroprevalence studies have been conducted over the past two decades. The World Health Organization recommends integrating ...
  • Hepatitis B virus infection in post-vaccination South Africa : occult HBV infection and circulating surface gene variants 
    Amponsah-Dacosta, Edina; Lebelo, Ramokone L.; Rakgole, J. Nare; Selabe, Selokela G.; Gededzha, Maemu P.; Mayaphi, Simnikiwe Horatious; Powell, Eleanor A.; Blackard, Jason T.; Mphahlele, M. Jeffrey (Elsevier, 2015-02)
    No abstract available
  • HHV-8 subtypes in South Africa : identification of a case suggesting a novel B variant 
    Treurnicht, Florette K.; Engelbrecht, Susan; Taylor, Maureen B.; Schneider, Johann W.; Janse van Rensburg, Estrelita (Wiley, 2002-02)
    Human herpesvirus 8 (HHV-8) has been identified as the causative agent for all forms of Kaposi's sarcoma and is also associated with the development of body cavity-based B-cell lymphomas and multicentric Castleman's disease. ...
  • High risk exposure to HIV among sexually active individuals who tested negative on rapid HIV tests in the Tshwane District of South Africa—the importance of behavioural prevention measures 
    Mayaphi, Simnikiwe Horatious; Martin, Desmond J.; Olorunju, Steve A.S.; Williams, Brian G.; Quinn, Thomas C.; Stoltz, Anton Carel (Public Library of Science, 2018-02-02)
    OBJECTIVE : To assess the prevalence of HIV risk behaviour among sexually active HIV sero-negative individuals in the Tshwane district of South Africa (SA). METHODS : Demographic and HIV risk behaviour data were collected ...
  • Histopathology and genotyping in infectious spondylitis of HIV- and HIV+ patients 
    Danaviah, S.; Govender, S.; Cassol, Sharon (Lippincott Williams and Wilkins, 2007-07)
    Approximately 2 million South Africans are HIV/TB coinfected, and many develop skeletal disease. The resurgence of spinal tuberculosis, including atypical forms, is due largely to HIV-associated immune suppression. We ...
  • HIV and influenza infection are associated with increased blood pneumococcal load : a prospective, hospital-based observational study in South Africa, 2009–2011 
    Wolter, Nicole; Cohen, Cheryl; Tempia, Stefano; Madhi, Shabir A.; Venter, Marietjie; Moyes, Jocelyn; Walaza, Sibongile; Kgokong, Babatyi; Groome, Michelle; Du Plessis, Mignon; Pretorius, Marthi Andréa; Dawood, Halima; Kahn, Kathleen; Variava, Ebrahim; Klugman, Keith P.; Von Gottberg, Anne (Oxford University Press, 2014-01)
    BACKGROUND : Increased pneumococcal loads are associated with severe outcomes. We determined the prevalence of pneumococcal DNA in blood specimens from patients hospitalized with acute lower respiratory tract infection and ...
  • HIV diagnostic challenges in breast-fed infants of mothers on antiretroviral therapy 
    Strehlau, Renate; Paximadis, Maria; Patel, Faeezah; Burke, Megan; Technau, Karl-Gunter; Shiau, Stephanie; Abrams, Elaine J.; Sherman, Gayle G.; Hunt, Gillian; Ledwaba, Johanna; Mazanderani, Ahmad Haeri; Tiemessen, Caroline T.; Kuhn, Louise (Wolters Kluwer Health, 2019-09)
    BACKGROUND : Prompt initiation of antiretroviral therapy (ART) for HIV-infected infants is strongly recommended but diagnostic confirmation is important as committing children to life-long ART carries serious health and ...