Research Articles (Medical Virology)

Research Articles (Medical Virology)

 

Recent Submissions

  • Weber, Natalie; Nagy, Martina; Markotter, Wanda; Schaer, Juliane; Puechmaille, Sebastien J.; Sutton, Jack; Davalos, Liliana M.; Dusabe, Marie-Claire; Ejotre, Imran; Fenton, M. Brock; Knornschild, Mirjam; Lopez-Baucells, Adria; Medellin, Rodrigo A.; Mubareka, Samira; Nsengimana, Olivier; O’Mara, M. Teague; Racey, Paul A.; Tuttle, Merlin; Twizeyimana, Innocent; Vicente-Santos, Amanda; Tschapka, Marco; Voigt, Christian C.; Wikelski, Martin; Dechmann, Dina K.N.; Reeder, DeeAnn M. (Royal Society, 2023-11)
    Africa experiences frequent emerging disease outbreaks among humans, with bats often proposed as zoonotic pathogen hosts. We comprehensively reviewed virus–bat findings from papers published between 1978 and 2020 to ...
  • Geldenhuys, Marike; Ross, Noam; Dietrich, Muriel; De Vries, J. Low; Mortlock, Marinda; Epstein, Jonathan H.; Weyer, Jacqueline; Paweska, Janusz Tadeusz; Markotter, Wanda (Nature Reseach, 2023-09)
    Novel coronavirus species of public health and veterinary importance have emerged in the first two decades of the twenty-first century, with bats identified as natural hosts for progenitors of many coronaviruses. Targeted ...
  • Ranchod, Heena; Howard, Wayne; Roux, Adele; Van Zyl, Walda B.; Ekermans, Pieter; Van den Berg, Sylvia; Seakamela, Lerato; Makua, Koketso; Yousif, Mukhlid; Sibiya, Rosinah; Du Plessis, Heleen; Phalane, Emmanuel; McCarthy, Kerrigan; Moonsamy, Shelina; Reynders, David; Hincks, Jeffrey; Suchard, Melinda S.; Du Plessis, Nicolette M. (Oxford University Press, 2024-01)
    Patients with severe primary immunodeficiency are at risk for complications from live-attenuated vaccines. Here, we report a case of a vaccine-associated paralytic polio and Bacille Calmette-Guérin disease in a 6-month-old ...
  • Szentivanyi, Tamara; Heintz, Anne-Caroline; Markotter, Wanda; Wassef, Jerome; Christe, Philippe; Glaizot, Olivier (Wiley, 2023-06)
    Bats are known reservoir hosts for a wide variety of parasites and pathogens, including bacteria and protozoans. Some of these pathogens are vector-borne, and although their role is poorly studied, ectoparasites may ...
  • Van Staden, Werdie; Nienaber, A.; Rossouw, T.; Turner, A.C. (Astrid); Filmalter, Cecilia Jacoba; Nel, Jan Gert; Bapela, S.; Beetge, Mia-Michaela; Blumenthal, Ryan; Castelyn, Camille De Villebois; De Witt-Jordaan, T.W. (Wilma); Dlagnekova, Antonia; Kotze, Carla; Mangwane, S.; Napoles, Lizeka; Somers, R.; Sykes, Leanne M.; Van Zyl, W.B.; Venter, Marietjie; Uys, Andre; Warren, Nichola (South African Medical Association, 2023-04)
    This article provides ethical guidance on using race in health research as a variable or in defining the study population. To this end, a plain, non-exhaustive checklist is provided for researchers and research ethics ...
  • Mettenleiter, Thomas C.; Markotter, Wanda; Charron, Dominique F.; Adisasmito, Wiku B.; Almuhairi, Salama; Behravesh, Casey Barton; Bilivogui, Pepe; Bukachi, Salome A.; Casas, Natalia; Becerra, Natalia Cediel; Chaudhary, Abhishek; Ciacci Zanella, Janice R.; Cunningham, Andrew A.; Dar, Osman; Debnath, Nitish; Dungu, Baptiste; Farag, Elmoubasher; Gao, George F.; Hayman, David T.S.; Khaitsa, Margaret; Koopmans, Marion P.G.; Machalaba, Catherine; Mackenzie, John S.; Morand, Serge; Smolenskiy, Vyacheslav; Zhou, Lei (BMC, 2023-12)
    No abstract available.
  • Hayman, David T.S.; Adisasmito, Wiku B.; Almuhairi, Salama; Behravesh, Casey Barton; Bilivogui, Pépé; Bukachi, Salome A.; Casas, Natalia; Becerra, Natalia Cediel; Charron, Dominique F.; Chaudhary, Abhishek; Ciacci Zanella, Janice R.; Cunningham, Andrew A.; Dar, Osman; Debnath, Nitish; Dungu, Baptiste; Farag, Elmoubasher; Gao, George F.; Khaitsa, Margaret; Machalaba, Catherine; Mackenzie, John S.; Markotter, Wanda; Mettenleiter, Thomas C.; Morand, Serge; Smolenskiy, Vyacheslav; Zhou, Lei; Koopmans, Marion (Elsevier, 2023-12)
    The health of humans, domestic and wild animals, plants, and the environment are inter-dependent. Global anthropogenic change is a key driver of disease emergence and spread and leads to biodiversity loss and ecosystem ...
  • Page, N.A. (Nicola); Netshikweta, Rembuluwani; Tate, Jacqueline E.; Madhi, Shabir A.; Parashar, Umesh D.; Groome, Michelle J. (Oxford University Press, 2023-09)
    A matched case-control evaluated infectious etiologies in children <3 years in post-rotavirus vaccine intussusception surveillance. Adenovirus and adenovirus types C, A, and B were detected more frequently in cases versus ...
  • Venter, Marietjie (Nature Research, 2023-06)
    Collaboration and openness are essential to minimize the risks of future pandemics, says the World Health Organization’s scientific advisory group, SAGO.
  • Kribi, Sarah; Toure, Fidele; Mendes, Adriano; Sanou, Soufiane; Some, Arsene; Aminou, Abdoul M.; Belarbi, Essia; Griessel, Rosemary; Hema, Arsene; Kabore, Firmin; Pitzinger, Paul; Strydom, Amy; Vietor, Ann Christin; Traore, Korotimi; Zongo, Arsene; Anoh, Etile A.; Grossegesse, Marica; Hofmann, Natalie; Ouangraoua, Soumeya; Poda, Armel; Kagone, Therese; Schubert, Grit; Eckmanns, Tim; Venter, Marietjie; Leendertz, Fabian; Akoua-Koffi, Chantal; Tomczyk, Sara (Oxford University Press, 2023-03)
    BACKGROUND : Reports on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spread across Africa have varied, including among healthcare workers (HCWs). This study assessed the comparative SARS-CoV-2 burden and ...
  • Coertse, Jessica; Viljoen, Natalie; Weyer, Jacqueline; Markotter, Wanda (MDPI, 2023-07-18)
    Novel lyssaviruses, the causative agents of rabies, continue to be described mostly due to increased surveillance in bat hosts. Biologicals for the prevention of rabies in humans have, however, remained largely unchanged ...
  • Snyman, Leon Cornelius; Richter, Karin Louise; widowi; Dreyer, Gerrit; Botha, Matthys Hendrik; Van der Merwe, F. Haynes; Visser, Cathy; Dreyer, Greta (BMJ Publishing, 2023-05)
    OBJECTIVES : Cervical cancer is preventable and caused by persistent infection with oncogenic human papilloma virus (HPV) types. HPV screening is more sensitive and is the preferred screening test. HPV screening data are ...
  • Machalaba, Catherine; Adisasmito, Wiku B.; Almuhairi, Salama; Behravesh, Casey Barton; Bilivogui, Pepe; Bukachi, Salome A.; Becerra, Natalia Cediel; Charron, Dominique F.; Chaudhary, Abhishek; Zanella, Janice R. Ciacci; Cunningham, Andrew A.; Dar, Osman; Debnath, Nitish; Dungu, Baptiste; Farag, Elmoubasher; Gao, George F.; Hayman, David T.S.; Khaitsa, Margaret; Koopmans, Marion P.G.; Mackenzie, John S.; Markotter, Wanda; Mettenleiter, Thomas C.; Morand, Serge; Smolenskiy, Vyacheslav; Zhou, Lei (Elsevier, 2023-02)
    The importance of integrated One Health approaches to reduce the likelihood and impacts of emerging infectious disease outbreaks has been widely accepted, as the Lancet series on One Health emphasises.1–4 However, ...
  • Omoga, Dorcus Caroline Achieng; Tchouassi, David P.; Venter, Marietjie; Ogola, Edwin O.; Osalla, Josephine; Kopp, Anne; Slothouwer, Inga; Torto, Baldwyn; Junglen, Sandra; Sang, Rosemary (MDPI, 2023-09-03)
    Crimean–Congo haemorrhagic fever virus (CCHFV) is the causative agent of CCHF, a fatal viral haemorrhagic fever disease in humans. The maintenance of CCHFV in the ecosystem remains poorly understood. Certain tick species ...
  • Viljoen, Natalie; Weyer, Jacqueline; Coertse, Jessica; Markotter, Wanda (MDPI, 2023-10-04)
    We report the genetic characterization of two potentially novel rabies-related lyssaviruses identified from bats in Limpopo province, South Africa. Matlo bat lyssavirus (MBLV) was identified in two Miniopterus natalensis ...
  • Fellows, Tamika; Page, Nicola Anne; Fix, Alan; Flores, Jorge; Cryz, Stanley; McNeal, Monica; Iturriza-Gomara, Miren; Groome, Michelle J. (MDPI, 2023-08-25)
    A correlate of protection for rotavirus (RV) has not been consistently identified. Shedding of RV following an oral rotavirus vaccine (ORV) challenge has been investigated as a potential model to assess protection of ...
  • Viana, Raquel; Moyo, Sikhulile; Amoako, Daniel G.; Tegally, Houriiyah; Scheepers, Cathrine; Althaus, Christian L.; Anyaneji, Ugochukwu J.; Bester, Phillip A.; Boni, Maciej F.; Chand, Mohammed; Choga, Wonderful T.; Colquhoun, Rachel; Davids, Michaela; Deforche, Koen; Doolabh, Deelan; Du Plessis, Louis; Engelbrecht, Susan; Everatt, Josie; Giandhari, Jennifer; Giovanetti, Marta; Hardie, Diana; Hill, Verity; Hsiao, Nei-Yuan; Iranzadeh, Arash; Ismail, Arshad; Joseph, Charity; Joseph, Rageema; Koopile, Legodile; Pond, Sergei L. Kosakovsky; Kraemer, Moritz U.G.; Kuate-Lere, Lesego; Laguda-Akingba, Oluwakemi; Lesetedi-Mafoko, Onalethatha; Lessells, Richard; Lockman, Shahin; Lucaci, Alexander G.; Maharaj, Arisha; Mahlangu, Boitshoko; Maponga, Tongai; Mahlakwane, Kamela; Makatini, Zinhle; Marais, Gert; Maruapula, Dorcas; Masupu, Kereng; Matshaba, Mogomotsi; Mayaphi, Simnikiwe; Mbhele, Nokuzola; Mbulawa, Mpaphi B.; Mendes, Adriano; Mlisana, Koleka; Mnguni, Anele; Mohale, Thabo; Moir, Monika; Moruisi, Kgomotso; Mosepele, Mosepele; Motsatsi, Gerald; Motswaledi, Modisa S.; Mphoyakgosi, Thongbotho; Msomi, Nokukhanya; Mwangi, Peter N.; Naidoo, Yeshnee; Ntuli, Noxolo; Nyaga, Martin; Olubayo, Lucier; Pillay, Sureshnee; Radibe, Botshelo; Ramphal, Yajna; Ramphal, Upasana; San, James E.; Scott, Lesley; Shapiro, Roger; Smith-Lawrence, Pamela; Stevens, Wendy; Strydom, Amy; Subramoney, Kathleen; Tebeila, Naume; Tshiabuila, Derek; Tsui, Joseph; Van Wyk, Stephanie; Weaver, Steven; Wibmer, Constantinos K.; Wilkinson, Eduan; Wolter, Nicole; Zarebski, Alexander E.; Zuze, Boitumelo; Goedhals, Dominique; Preise, Wolfgang; Treurnicht, Florette; Venter, Marietjie; Williamson, Carolyn; Pybus, Oliver G.; Bhiman, Jinal; Glass, Allison; Martin, Darren P.; Rambaut, Andrew; Gaseitsiwe, Simani; Von Gottberg, Anne; De Oliveira, Tulio (Nature Research, 2022-03-24)
    The SARS-CoV-2 epidemic in southern Africa has been characterized by three distinct waves. The first was associated with a mix of SARS-CoV-2 lineages, while the second and third waves were driven by the Beta (B.1.351) ...
  • Tegally, Houriiyah; Moir, Monika; Everatt, Josie; Giovanetti, Marta; Scheepers, Cathrine; Wilkinson, Eduan; Subramoney, Kathleen; Makatini, Zinhle; Moyo, Sikhulile; Amoako, Daniel G.; Baxter, Cheryl; Althaus, Christian L.; Anyaneji, Ugochukwu J.; Kekana, Dikeledi; Viana, Raquel; Giandhari, Jennifer; Lessells, Richard; Maponga, Tongai; Maruapula, Dorcas; Choga, Wonderful; Matshaba, Mogomotsi; Mbulawa, Mpaphi B.; Msomi, Nokukhanya; NGS-SA consortium; Naidoo, Yeshnee; Pillay, Sureshnee; Sanko, Tomasz Janusz; San, James E.; Scott, Lesley; Singh, Lavanya; Magini, Nonkululeko A.; Smith-Lawrence, Pamela; Stevens, Wendy; Dor, Graeme; Tshiabuila, Derek; Wolter, Nicole; Preiser, Wolfgang; Treurnicht, Florette K.; Venter, Marietjie; Chiloane, Georginah; McIntyre, Caitlyn; O’Toole, Aine; Ruis, Christopher; Peacock, Thomas P.; Roemer, Cornelius; Pond, Sergei L. Kosakovsky; Williamson, Carolyn; Pybus, Oliver G.; Bhiman, Jinal N.; Glass, Allison; Martin, Darren P.; Jackson, Ben; Rambaut, Andrew; Laguda-Akingba, Oluwakemi; Gaseitsiwe, Simani; Von Gottberg, Anne; De Oliveira, Tulio; Bester, Armand Phillip; Claassen, Mathilda; Doolabh, Deelan; Mudau, Innocent; Mbhele, Nokuzola; Engelbrecht, Susan; Goedhals, Dominique; Hardie, Diana; Hsiao, Nei-Yuan; Iranzadeh, Arash; Ismail, Arshad; Joseph, Rageema; Maharaj, Arisha; Mahlangu, Boitshoko; Mahlakwane, Kamela; Davis, Ashlyn; Marais, Gert; Mlisana, Koleka; Mnguni, Anele; Mohale, Thabo; Motsatsi, Gerald; Mwangi, Peter; Ntuli, Noxolo; Nyaga, Martin; Olubayo, Luicer; Radibe, Botshelo; Ramphal, Yajna; Ramphal, Upasana; Strasheim, Wilhelmina; Tebeila, Naume; Van Wyk, Stephanie; Wilson, Shannon; Lucaci, Alexander G.; Weaver, Steven; Maharaj, Akhil; Pillay, Yusasha; Davids, Michaela; Mendes, Adriano; Mayaphi, Simnikiwe (Nature Research, 2022-09)
    Three lineages (BA.1, BA.2 and BA.3) of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant of concern predominantly drove South Africa’s fourth Coronavirus Disease 2019 (COVID-19) wave. We ...
  • Punchoo, Rivak; Bhoora, Sachin; Bangalee, Avania (International Federation of Clinical Chemistry and Laboratory Medicine, 2022-08)
    The Coronavirus Disease 2019 (COVID-19) pandemic is caused by the SARS-CoV-2 RNA virus. Nucleic acid amplification testing (NAAT) is the mainstay to confirm infection. A large number of reverse transcriptase polymerase ...
  • Scheepers, Cathrine; Everatt, Josie; Amoako, Daniel G.; Tegally, Houriiyah; Wibmer, Constantinos Kurt; Mnguni, Anele; Ismail, Arshad; Mahlangu, Boitshoko; Lambson, Bronwen E.; Martin, Darren P.; Wilkinson, Eduan; San, James Emmanuel; Giandhari, Jennifer; Manamela, Nelia; Ntuli, Noxolo; Kgagudi, Prudence; Cele, Sandile; Richardson, Simone I.; Pillay, Sureshnee; Mohale, Thabo; Ramphal, Upasana; Naidoo, Yeshnee; Khumalo, Zamantungwa Thobeka Happiness; Kwatra, Gaurav; Gray, Glenda; Bekker, Linda‑Gail; Madhi, Shabir A.; Baillie, Vicky; Van Voorhis, Wesley C.; Treurnicht, Florette K.; Venter, Marietjie; Mlisana, Koleka; Wolter, Nicole; Sigal, Alex; Williamson, Carolyn; Hsiao, Nei-yuan; Msomi, Nokukhanya; Maponga, Tongai; Preiser, Wolfgang; Makatini, Zinhle; Lessells, Richard; Moore, Penny L.; De Oliveira, Tulio; Von Gottberg, Anne; Bhiman, Jinal N. (Nature Research, 2022-04-08)
    Global genomic surveillance of SARS-CoV-2 has identified variants associated with increased transmissibility, neutralization resistance and disease severity. Here we report the emergence of the PANGO lineage C.1.2, ...

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