Medical Virology

Medical Virology

 

The mission of the Department of Medical Virology is to conduct medical research and provide diagnostic services in virology and to train technologists, pathologists and medical scientists who will be able to make a significant contribution in the field of virology in South Africa.

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  • Rademan, Rochelle; Markotter, Wanda; Paweska, Janusz Tadeusz; Jansen van Vuren, Petrus (Elsevier, 2019-04)
    Zika (ZIKV) and Spondweni viruses (SPOV) are closely related mosquito borne flaviviruses in the Spondweni serogroup. The co-circulation and similar disease presentation following ZIKV and SPOV infection necessitates the ...
  • Kremer, Wieke W.; Van Zummeren, Marjolein; Novianti, Putri W.; Richter, Karin Louise; Verlaat, Wina; Snijders, Peter J.F.; Heideman, Danielle A.M.; Steenbergen, Renske D.M.; Dreyer, Greta; Meijer, Chris J.L.M. (Wiley Open Access, 2018-08)
    INTRODUCTION : To evaluate the performance of hypermethylation analysis of ASCL1, LHX8 and ST6GALNAC5 in physician-taken cervical scrapes for detection of cervical cancer and cervical intraepithelial neoplasia (CIN) grade ...
  • Maes, Piet; Adkins, Scott; Alkhovsky, Sergey V.; Avšič-Županc, Tatjana; Ballinger, Matthew J.; Bente, Dennis A.; Beer, Martin; Bergeron, Éric; Blair, Carol D.; Briese, Thomas; Buchmeier, Michael J.; Burt, Felicity J.; Calisher, Charles H.; Charrel, Rémi N.; Choi, Il Ryong; Clegg, J. Christopher S.; De la Torre, Juan Carlos; De Lamballerie, Xavier; DeRisi, Joseph L.; Digiaro, Michele; Drebot, Mike; Ebihara, Hideki; Elbeaino, Toufic; Ergünay, Koray; Fulhorst, Charles F.; Garrison, Aura R.; Gāo, George Fú; Gonzalez, Jean-Paul J.; Groschup, Martin H.; Günther, Stephan; Haenni, Anne-Lise; Hall, Roy A.; Hewson, Roger; Hughes, Holly R.; Jain, Rakesh K.; Jonson, Miranda Gilda; Junglen, Sandra; Klempa, Boris; Klingström, Jonas; Kormelink, Richard; Lambert, Amy J.; Langevin, Stanley A.; Lukashevich, Igor S.; Marklewitz, Marco; Martelli, Giovanni P.; Mielke-Ehret, Nicole; Mirazimi, Ali; Mühlbach, Hans-Peter; Naidu, Rayapati; Nunes, Márcio Roberto Teixeira; Palacios, Gustavo; Papa, Anna; Paweska, Janusz Tadeusz; Peters, Clarence J.; Plyusnin, Alexander; Radoshitzky, Sheli R.; Resende, Renato O.; Romanowski, Víctor; Sall, Amadou Alpha; Salvato, Maria S.; Sasaya, Takahide; Schmaljohn, Connie; Shí, Xiǎohóng; Shirako, Yukio; Simmonds, Peter; Sironi, Manuela; Song, Jin-Won; Spengler, Jessica R.; Stenglein, Mark D.; Tesh, Robert B.; Turina, Massimo; Wèi, Tàiyún; Whitfield, Anna E.; Yeh, Shyi-Dong; Zerbini, F. Murilo; Zhang, Yong-Zhen; Zhou, Xueping; Kuhn, Jens H. (Springer, 2019-03)
    In October 2018, the order Bunyavirales was amended by inclusion of the family Arenaviridae, abolishment of three families, creation of three new families, 19 new genera, and 14 new species, and renaming of three genera ...
  • Treurnicht, Florette K.; Buys, Amelia; Tempia, Stefano; Seleka, Mpho; Cohen, Adam L.; Walaza, Sibongile; Glass, Allison J.; Rossouw, Inez; McAnerney, Johanna; Blumberg, Lucille; Cohen, Cheryl; Venter, Marietjie (Wiley Open Access, 2019-01)
    BACKGROUND : Data on the susceptibility of influenza viruses from South Africa to neuraminidase inhibitors (NAIs) are scarce, and no extensive analysis was done. OBJECTIVES : We aimed to determine oseltamivir and zanamivir ...
  • Magwira, C.A. (Cliff); Taylor, Maureen B. (Elsevier, 2018-06)
    The introduction of oral rotavirus vaccines (ORVVs) has led to a reduction in number of hospitalisations and deaths due to rotavirus (RV) infection. However, the efficacy of the vaccines has been varied with low-income ...
  • Schaub, Roxane; Badiou, Stephanie; Viljoen, Johannes; Dujols, Pierre; Bollore, Karine; Van de Perre, Philippe; Newell, Marie‑Louise; Bland, Ruth; Nagot, Nicolas; Tuaillon, Edouard (BMC, 2018-10)
    BACKGROUND : Subclinical mastitis (SCM) is relatively common in lactating women and may be associated with HIV shedding in breast milk. The potential association between HIV infection and breast milk immunologic factors ...
  • Nadan, Sandrama; Taylor, Maureen B.; Groome, Michelle J.; Cohen, Cheryl; Madhi, Shabir A.; Page, N.A. (Nicola) (Wiley, 2018-09)
    BACKGROUND : The epidemiology of human astroviruses (HAstVs) in hospitalised patients less than 5 years of age from selected sites in South Africa was investigated. Diarrheagenic stool specimens collected from April 2009 ...
  • Mazanderani, Ahmad Haeri; Sherman, G.G.; Moyo, F.; Goga, Ameena Ebrahim; Feucht, Ute Dagmar (Health and Medical Publishing Group, 2018-09)
    BACKGROUND. Currently there is no unique patient identification system in the South African public health sector. Therefore, routine laboratory data cannot effectively be de-duplicated, thereby hampering surveillance of ...
  • Von Mollendorf, Claire; Hellferscee, Orienka; Valley-Omar, Ziyaad; Treurnicht, Florette K.; Walaza, Sibongile; Martinson, Neil A.; Lebina, Limakatso; Mothlaoleng, Katlego; Mahlase, Gethwana; Variava, Ebrahim; Cohen, Adam L.; Venter, Marietjie; Cohen, Cheryl; Tembo, Stefano (Oxford University Press, 2018-10)
    BACKGROUND : Prolonged shedding of influenza viruses may be associated with increased transmissibility and resistance mutation acquisition due to therapy. We compared duration and magnitude of influenza shedding between ...
  • Sule, Waidi F.; Oluwayelu, Daniel O.; Hernandez-Triana, Luis M.; Fooks, Anthony R.; Venter, Marietjie; Johnson, Nicholas (BioMed Central, 2018-07-13)
    West Nile virus (WNV) is the aetiological agent of the mosquito-borne zoonotic disease West Nile fever. The virus, first isolated in Uganda in 1937, evolved into two distinct lineages in sub-Saharan Africa (SSA) ...
  • Topazian, Hillary M.; Kundu, Debanjali; Peebles, Kathryn; Ramos, Silvina; Morgan, Karen; Kim, Chan Joo; Richter, Karin Louise; Brewer, Noel T.; Peris, Mercè; Smith, Jennifer S. (Elsevier, 2018-12)
    STUDY OBJECTIVE : To assess adolescent health care providers’ recommendations for, and attitudes towards human papillomavirus (HPV) vaccination in 5 countries. DESIGN : In-depth interviews of adolescent health care providers, ...
  • Jansen van Vuren, Petrus; Allam, Mushal; Wiley, Michael R.; Ismail, Arshad; Storm, Nadia; Birkhead, Monica; Markotter, Wanda; Palacios, Gustavo; Paweska, Janusz Tadeusz (Nature Publishing Group, 2018-06-25)
    Recently a number of novel adenoviruses have been isolated from diverse bat species and from diverse geographical locations. We describe the isolation of a novel adenovirus (Family Adenoviridae, genus Mastadenovirus) ...
  • Dietrich, Muriel; Kearney, Teresa; Seamark, E.C.J. (Ernest); Paweska, Janusz Tadeusz; Markotter, Wanda (Royal Society Publishing, 2018)
    Seasonal reproduction is a period of extreme physiological and behavioural changes, yet we know little about how it may affect host microbial communities (i.e. microbiota) and pathogen transmission. Here, we investigated ...
  • Chepkorir, Edith; Venter, Marietjie; Lutomiah, J.; Mulwa, F.; Arum, S.; Tchouassi, D.P.; Sang, R. (Elsevier, 2018-10)
    INTRODUCTION : Yellow fever (YF) and dengue (DEN) viruses are important re-emerging mosquito-borne viruses sharing similar vectors and reservoirs. The last documented YF outbreak in Kenya occurred in 1992–95. However, YF ...
  • Mouatcho, Joel; Cornel, Anthony J.; Dahan‑Moss, Yael; Koekemoer, Lizette L.; Coetzee, Maureen; Braack, L.E.O. (BioMed Central, 2018-05-15)
    BACKGROUND : The Anopheles gambiae sensu lato (s.l.) and Anopheles funestus s.l. species complexes contain the most important malaria vectors in Africa. Within the An. funestus group of at least 11 African species, the ...
  • Dietrich, Muriel; Gomard, Yann; Lagadec, Erwan; Ramasindrazana, Beza; Le Minter, Gildas; Guernier, Vanina; Benlali, Aude; Rocamora, Gerard; Markotter, Wanda; Goodman, Steven M.; Dellagi, Koussay; Tortosa, Pablo (Nature Publishing Group, 2018-04-04)
    Understanding the processes driving parasite assemblages is particularly important in the context of zoonotic infectious diseases. Leptospirosis is a widespread zoonotic bacterial infection caused by pathogenic species ...
  • Venter, Marietjie (Elsevier, 2018-02)
    Several African arboviruses have emerged over the past decade in new regions where they caused major outbreaks in humans and/or animals including West Nile virus, Chikungunya virus and Zika virus. This raise questions ...
  • Venter, Marietjie; Pretorius, Marthi A.; Fuller, James A.; Botha, Elizabeth; Rakgotho, Mpho; Stivaktas, Voula; Weyer, Camilla Theresa; Romito, Marco; Williams, J.H. (June Heather) (Centers for Disease Control and Prevention, 2017-12)
    During 2008–2015 in South Africa, we conducted West Nile virus surveillance in 1,407 animals with neurologic disease and identified mostly lineage 2 cases in horses (7.4%, 79/1,069), livestock (1.5%, 2/132), and wildlife ...
  • Tempia, Stefano; Walaza, Sibongile; Moyes, Jocelyn; Cohen, Adam L.; Von Mollendorf, Claire; Treurnicht, Florette K.; Venter, Marietjie; Pretorius, Marthi A.; Hellferscee, Orienka; Mtshali, Senzo; Seleka, Mpho; Tshangela, Akhona; Nguweneza, Athermon; McAnerney, Johanna M.; Wolter, Nicole; Von Gottberg, Anne; Dawood, Halima; Variava, Ebrahim; Madhi, Shabir A.; Cohen, Cheryl (Oxford University Press, 2017)
    BACKGROUND : Data on risk factors for influenza-associated hospitalizations in low- and middle-income countries are limited. METHODS : We conducted active syndromic surveillance for hospitalized severe acute respiratory ...
  • Sibanda, Mthokozisi Mayibongwe; Focke, Walter Wilhelm; Braack, L.E.O.; Leuteritz, Andreas; Brünig, Harald; Tran, Nguyen Hoai An; Wieczorek, Florian; Trümper, Wolfgang (Elsevier, 2018-10)
    Core-sheath structured fibres were developed for application as part of an alternative malaria vector control intervention aimed at reducing outdoor malaria transmission. The fibres were prepared by melt spinning of high ...

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