Medical Virology

Medical Virology

 

The mission of the Department of Medical Virology is to conduct medical research and provide diagnostic services in virology and to train technologists, pathologists and medical scientists who will be able to make a significant contribution in the field of virology in South Africa.

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Recent Submissions

  • Dietrich, Muriel; Kearney, Teresa; Seamark, E.C.J. (Ernest); Paweska, Janusz Tadeusz; Markotter, Wanda (Royal Society Publishing, 2018)
    Seasonal reproduction is a period of extreme physiological and behavioural changes, yet we know little about how it may affect host microbial communities (i.e. microbiota) and pathogen transmission. Here, we investigated ...
  • Chepkorir, Edith; Venter, Marietjie; Lutomiah, J.; Mulwa, F.; Arum, S.; Tchouassi, D.P.; Sang, R. (Elsevier, 2018-10)
    INTRODUCTION : Yellow fever (YF) and dengue (DEN) viruses are important re-emerging mosquito-borne viruses sharing similar vectors and reservoirs. The last documented YF outbreak in Kenya occurred in 1992–95. However, YF ...
  • Mouatcho, Joel; Cornel, Anthony J.; Dahan‑Moss, Yael; Koekemoer, Lizette L.; Coetzee, Maureen; Braack, L.E.O. (BioMed Central, 2018-05-15)
    BACKGROUND : The Anopheles gambiae sensu lato (s.l.) and Anopheles funestus s.l. species complexes contain the most important malaria vectors in Africa. Within the An. funestus group of at least 11 African species, the ...
  • Dietrich, Muriel; Gomard, Yann; Lagadec, Erwan; Ramasindrazana, Beza; Le Minter, Gildas; Guernier, Vanina; Benlali, Aude; Rocamora, Gerard; Markotter, Wanda; Goodman, Steven M.; Dellagi, Koussay; Tortosa, Pablo (Nature Publishing Group, 2018-04-04)
    Understanding the processes driving parasite assemblages is particularly important in the context of zoonotic infectious diseases. Leptospirosis is a widespread zoonotic bacterial infection caused by pathogenic species ...
  • Venter, Marietjie (Elsevier, 2018-02)
    Several African arboviruses have emerged over the past decade in new regions where they caused major outbreaks in humans and/or animals including West Nile virus, Chikungunya virus and Zika virus. This raise questions ...
  • Venter, Marietjie; Pretorius, Marthi A.; Fuller, James A.; Botha, Elizabeth; Rakgotho, Mpho; Stivaktas, Voula; Weyer, Camilla Theresa; Romito, Marco; Williams, J.H. (June Heather) (Centers for Disease Control and Prevention, 2017-12)
    During 2008–2015 in South Africa, we conducted West Nile virus surveillance in 1,407 animals with neurologic disease and identified mostly lineage 2 cases in horses (7.4%, 79/1,069), livestock (1.5%, 2/132), and wildlife ...
  • Tempia, Stefano; Walaza, Sibongile; Moyes, Jocelyn; Cohen, Adam L.; Von Mollendorf, Claire; Treurnicht, Florette K.; Venter, Marietjie; Pretorius, Marthi A.; Hellferscee, Orienka; Mtshali, Senzo; Seleka, Mpho; Tshangela, Akhona; Nguweneza, Athermon; McAnerney, Johanna M.; Wolter, Nicole; Von Gottberg, Anne; Dawood, Halima; Variava, Ebrahim; Madhi, Shabir A.; Cohen, Cheryl (Oxford University Press, 2017)
    BACKGROUND : Data on risk factors for influenza-associated hospitalizations in low- and middle-income countries are limited. METHODS : We conducted active syndromic surveillance for hospitalized severe acute respiratory ...
  • Sibanda, Mthokozisi Mayibongwe; Focke, Walter Wilhelm; Braack, L.E.O.; Leuteritz, Andreas; Brünig, Harald; Tran, Nguyen Hoai An; Wieczorek, Florian; Trümper, Wolfgang (Elsevier, 2018-10)
    Core-sheath structured fibres were developed for application as part of an alternative malaria vector control intervention aimed at reducing outdoor malaria transmission. The fibres were prepared by melt spinning of high ...
  • Sekwadi, P.G.; Ravhuhali, K.G.; Mosam, A.; Essel, V.; Ntshoe, G.M.; Rakgantso, A.M.; McCarthy, K.; Mans, Janet; Taylor, Maureen B.; Page, Nicola; Govender, N. (Cambridge University Press, 2018-07)
    An unexpected increase in gastroenteritis cases was reported by healthcare workers on the KwaZulu-Natal Coast, South Africa, January 2017 with >600 cases seen over a 3-week period. A case–control study was conducted to ...
  • Tempia, Stefano; Walaza, Sibongile; Moyes, Jocelyn; Cohen, Adam L.; Von Mollendorf, Claire; McMorrow, Meredith L.; Mhlanga, Sarona; Treurnicht, Florette K.; Venter, Marietjie; Pretorius, Marthi A.; Hellferscee, Orienka; Wolter, Nicole; Von Gottberg, Anne; Nguweneza, Arthemon; McAnerney, Johanna M.; Dawood, Halima; Variava, Ebrahim; Madhi, Shabir A.; Cohen, Cheryl (Wiley Open Access, 2018-05)
    BACKGROUND : The attributable fraction of influenza virus detection to illness (INF-AF) and the duration of symptoms as a surveillance inclusion criterion could potentially have substantial effects on influenza disease ...
  • Moyo, F.; Mazanderani, Ahmad Haeri; Bhardwaj, S.; Mhlongo, O.B.; Kufa, T.; Ng’oma, K.; Smith, B.A.; Sherman, G.G. (Health and Medical Publishing Group, 2018-04)
    BACKGROUND. Identifying and addressing gaps in the prevention of mother-to-child transmission of HIV (PMTCT) is required if South Africa (SA) is to achieve targets for eliminating MTCT (eMTCT). Potential PMTCT gaps that ...
  • Geldenhuys, Marike; Mortlock, Marinda; Weyer, Jacqueline; Bezuidt, K.I.O. (Keoagile Ignatius Oliver); Seamark, E.C.J. (Ernest); Kearney, Teresa; Gleasner, Cheryl; Erkkila, Tracy H.; Cui, Helen; Markotter, Wanda (Public Library of Science, 2018-03-26)
    Species within the Neoromicia bat genus are abundant and widely distributed in Africa. It is common for these insectivorous bats to roost in anthropogenic structures in urban regions. Additionally, Neoromicia capensis ...
  • Maes, Piet; Alkhovsky, Sergey V.; Bào, Yīmíng; Beer, Martin; Birkhead, Monica; Briese, Thomas; Buchmeier, Michael J.; Calisher, Charles H.; Charrel, Rémi N.; Choi, Il Ryong; Clegg, Christopher S.; De la Torre, Juan Carlos; Delwart, Eric; DeRisi, Joseph L.; Di Bello, Patrick L.; Di Serio, Francesco; Digiaro, Michele; Dolja, Valerian V.; Drosten, Christian; Druciarek, Tobiasz Z.; Du, Jiang; Ebihara, Hideki; Elbeaino, Toufic; Gergerich, Rose C.; Gillis, Amethyst N.; Gonzalez, Jean-Paul J.; Haenni, Anne-Lise; Hepojoki, Jussi; Hetzel, Udo; Hồ, Thiện; Hóng, Ní; Jain, Rakesh K.; Jansen van Vuren, Petrus; Jin, Qi; Jonson, Miranda Gilda; Junglen, Sandra; Keller, Karen E.; Kemp, Alan; Kipar, Anja; Kondov, Nikola O.; Koonin, Eugene V.; Kormelink, Richard; Korzyukov, Yegor; Krupovic, Mart; Lambert, Amy J.; Laney, Alma G.; LeBreton, Matthew; Lukashevich, Igor S.; Marklewitz, Marco; Markotter, Wanda; Martelli, Giovanni P.; Martin, Robert R.; Mielke-Ehret, Nicole; Mühlbach, Hans-Peter; Navarro, Beatriz; Ng, Terry Fei Fan; Nunes, Márcio Roberto Teixeira; Palacios, Gustavo; Paweska, Janusz Tadeusz; Peters, Clarence J.; Plyusnin, Alexander; Radoshitzky, Sheli R.; Romanowski, Víctor; Salmenperä, Pertteli; Salvato, Maria S.; Sanfaçon, Hélène; Sasaya, Takahide; Schmaljohn, Connie; Schneider, Bradley S.; Shirako, Yukio; Siddell, Stuart; Sironen, Tarja A.; Stenglein, Mark D.; Storm, Nadia; Sudini, Harikishan; Tesh, Robert B.; Tzanetakis, Ioannis E.; Uppala, Mangala; Vapalahti, Olli; Vasilakis, Nikos; Walker, Peter J.; Wáng, Guópíng; Wáng, Lìpíng; Wáng, Yànxiăng; Wèi, Tàiyún; Wiley, Michael R.; Wolf, Yuri I.; Wolfe, Nathan D.; Wú, Zhìqiáng; Xú, Wénxìng; Yang, Li; Yāng, Zuòkūn; Yeh, Shyi-Dong; Zhāng, Yǒng-Zhèn; Zhèng, Yàzhōu; Zhou, Xueping; Zhū, Chénxī; Zirkel, Florian; Kuhn, Jens H. (Springer, 2018-08)
    In 2018, the family Arenaviridae was expanded by inclusion of 1 new genus and 5 novel species. At the same time, the recently established order Bunyavirales was expanded by 3 species. This article presents the updated ...
  • Kgaladi, Joe; Faber, Milosz; Dietzschold, Bernhard; Nel, Louis Hendrik; Markotter, Wanda (MDPI Publishing, 2017-08-09)
    Lagos bat virus (LBV) is a phylogroup II lyssavirus exclusively found in Africa. Previous studies indicated that this virus is lethal to mice after intracranial and intramuscular inoculation. The antigenic composition ...
  • Coetzer, Andre; Coertse, Jessica; Makalo, Mabusetsa Joseph; Molomo, Marosi; Markotter, Wanda; Nel, Louis Hendrik (MDPI Publishing, 2017-07-19)
    Rabies is widespread throughout Africa and Asia, despite the fact that the control and elimination of this disease has been proven to be feasible. Lesotho, a small landlocked country surrounded by South Africa, has been ...
  • Joao, Eva Dora; Strydom, Amy; O’Neill, Hester G.; Cuamba, Assa; Cassocera, Marta; Acacio, Sozinho; Mandomando, Inacio; Motanyane, Lithabiso; Page, Nicola; De Deus, Nilsa (Springer Verlag, 2018-01)
    In Mozambique rotavirus (RV) was shown to be the greatest cause of acute diarrhoea in infants from 0 to 11 months, and in 2015, national rotavirus vaccination was introduced. As with other developing countries, there is ...
  • Mayaphi, Simnikiwe H.; Martin, Desmond J.; Olorunju, Steve A.S.; Williams, Brian G.; Quinn, Thomas C.; Stoltz, Anton Carel (Public Library of Science, 2018-02-02)
    OBJECTIVE : To assess the prevalence of HIV risk behaviour among sexually active HIV sero-negative individuals in the Tshwane district of South Africa (SA). METHODS : Demographic and HIV risk behaviour data were collected ...
  • Braack, L.E.O.; De Almeida, Antonio Paulo Gouveia; Cornel, Anthony J.; Swanepoel, Robert; De Jager, Christiaan (BioMed Central, 2018-01-09)
    Key aspects of 36 mosquito-borne arboviruses indigenous to Africa are summarized, including lesser or poorly-known viruses which, like Zika, may have the potential to escape current sylvatic cycling to achieve greater ...
  • Storm, Nadia; Jansen van Vuren, Petrus; Markotter, Wanda; Paweska, Janusz Tadeusz (MDPI Publishing, 2018-02-10)
    Egyptian rousette bats (ERBs) are reservoir hosts for the Marburg virus (MARV). The immune dynamics and responses to MARV infection in ERBs are poorly understood, and limited information exists on the role of antibodies ...
  • Jansen van Vuren, Petrus; Wiley, Michael R.; Palacios, Gustavo; Storm, Nadia; Markotter, Wanda; Birkhead, Monica; Kemp, Alan; Paweska, Janusz Tadeusz (Microbiology Society, 2017-05)
    The Bunyaviridae family comprises viruses causing diseases of public and veterinary health importance, including viral haemorrhagic and arboviral fevers. We report the isolation, identification and genome characterization ...

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