Hand-foot-and-mouth disease caused by coxsackievirus A6 in a patient infected with HIV

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Authors

Mayaphi, Simnikiwe Horatious
Van Zyl, Walda B.
Sono, Tinah
Loots, Donovan P.
Taylor, Maureen B.

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MedPharm Publications

Abstract

Hand, foot and mouth disease (HFMD) is common in children ≤ 5 years of age, and is mainly caused by enterovirus 71 and coxsackievirus A16 (CVA6). A 12-year-old boy on treatment for human immunodeficiency virus (HIV) presented to an HIV clinic with fever and a rash on the palms and soles. The syphilis test were negative. Enterovirus was identified from a stool sample by PCR and characterised as as coxsackievirus A6(CVA6). The patient completely recovered a week later. CVA6 has recently been associated with HFMD. This case highlights the significance of the laboratory confirmation of suspected HFMD cases aand phylogenetic analysis of the identified virus.

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Keywords

Rash, Hand, foot and mouth disease (HFMD), Human immunodeficiency virus (HIV), Coxsackievirus A6 (CVA6), Enterovirus 71 ( EV71 )

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Citation

Mayaphi, S, Van Zyl, W, Sono, T, Loots, D & Taylor, M 2015, 'Hand-foot-and-mouth disease caused by coxsackievirus A6 in a patient infected with HIV', Southern African Journal of Infectious Diseases, 30, no. 2, pp. 67-69.