Abstract:
The use of nanocarriers for biomedical applications has been gaining interests from researchers
worldwide for the delivery of therapeutics in a controlled manner. These “smart” vehicles
enhance the dissolution and the bioavailability of drugs and enable their delivery to the target
site. Taking the potential toxicity into consideration, the incorporation of natural “green” materials,
derived from plants or microbial sources, in the nanocarriers fabrication, improve their safety and
biocompatibility. These green components can be used as a mechanical platform or as targeting
ligand for the payload or can play a role in the synthesis of nanoparticles. Several studies reported
the use of green based nanocarriers for the treatment of diseases such as cancer. This review article
provides a critical analysis of the different types of green nanocarriers and their synthesis mechanisms,
characterization, and their role in improving drug delivery of anticancer drugs to achieve
precision cancer treatment. Current evidence suggests that green-based nanocarriers can constitute
an effective treatment against cancer.
