General medicine discipline for specialist physicians.
Subdisciplines exist e.g. Gastroenterology, Pulmonology,
Nephrology, Rheumatology and Endocrinology.
Ahmed, Marwan Awad; Bailey, Helen D.; Pereira, Gavin; White, Scott W.; Wong, Kingsley; McNamara, Bridgette J.; Rheeder, Paul; Marriott, Rhonda; Shepherd, Carrington C.J.(Oxford University Press, 2023-10)
BACKGROUND :
Aboriginal and Torres Strait Islander (hereafter Aboriginal) women have a high prevalence of diabetes in pregnancy (DIP), which includes pre-gestational diabetes mellitus (PGDM) and gestational diabetes ...
Van der Mescht, Mieke Adri; Steel, Helen C.; De Beer, Zelda; Abdullah, Fareed; Ueckermann, Veronica; Anderson, Ronald; Rossouw, Theresa(Frontiers Media, 2023-08-14)
INTRODUCTION : SARS-CoV-2 elicits a hyper-inflammatory response that
contributes to increased morbidity and mortality in patients with COVID-19. In
the case of HIV infection, despite effective anti-retroviral therapy, ...
The kinetics of Fc-mediated functions following SARS-CoV-2 infection or
vaccination in people living with HIV (PLWH) are not known. We compared
SARS-CoV-2 spike-specific Fc functions, binding, and neutralization in ...
Richards, G.A.; Theron, Annette J.; Van den Bout, Jan Iman; Anderson, Ronald; Feldman, Charles; Van Zyl Smit, Richard; Chang, Ju-Wei; Tintinger, Gregory(European Respiratory Society, 2023-05)
BACKGROUND : Electronic cigarettes (ECs) are electronic aerosol delivery systems composed of nicotine and
various chemicals, which are widely used to facilitate smoking cessation. Although ECs are considered
safer than ...
A 56-year-old woman presented with a 2-year history of
chronic persistent right upper quadrant abdominal pain that
was associated with intermittent nausea, vomiting, and
unintentional weight loss. She had been on ...
Kgatle, Mankgopo; Chalwe, Joseph Musonda; Van der Westhuizen, Donald; Xu, Shuting; Damane, Botle Precious; Mathebela, Precious; Ueckermann, Veronica; Mayaphi, Simnikiwe; Rodrigues, Hosana Gomes; Moura-Alves, Pedro; Ndlovu, Honest; Mzizi, Yonwaba; Zongo, Lusanda; Hairwadzi, Henry; Vorster, Mariza; Zeevaart, Jan Rijn; Sathekge, Mike Machaba(MDPI, 2023-07-03)
A correlation between neutralization activity after severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) vaccination and protection against coronavirus disease 2019 (COVID-19)
has been demonstrated by several ...
Severe acute respiratory tract infections (SARIs) has been well described in South Africa with seasonal patterns described for influenza and respiratory syncytial virus (RSV), while others occur year-round (rhinovirus and ...
We report here on the process and findings of a research prioritisation exercise for universal health coverage (UHC) in South Africa,
conducted during the course of 2019. As plans to roll out National Health Insurance ...
BACKGROUND : The association between human papillomavirus (HPV) and cervical cancer is well established, and cervical cancer can be prevented through HPV vaccination. Little has been reported on the association between HPV ...
We report here on the process and findings of a research prioritisation exercise for universal health coverage (UHC) in South Africa,
conducted during the course of 2019. As plans to roll out National Health Insurance ...
BACKGROUND : HIV infection causes immune dysregulation affecting T-cell and monocyte
function, which may alter coronavirus disease 2019 (COVID-19) pathophysiology.
OBJECTIVES : We investigated the associations among ...
Munsami, Lyneshree; Schutte, Clara-Maria; De Villiers, Maryke; Hiesgen, Juliane(AOSIS, 2023-01-19)
BACKGROUND : The neuropsychiatric side effects of efavirenz occur mainly early during treatment
and are usually mild. A lesser-known and serious complication is late-onset efavirenz toxicity
causing ataxia and encephalopathy. ...
De Beer, Janetta Catharina; Snyman, Jacques; Ker, James A.; Miller-Janson, Helen; Stander, Marthinus(Elsevier, 2023-01)
OBJECTIVES : This study aimed to estimate the budget impact and affordability of empagliflozin added to usual care compared with usual care alone, in a diabetic population with established cardiovascular disease, from a ...
BACKGROUND : By October 2022, vaccination rates with at least one dose of a COVID-19 vaccine were low among adolescent girls aged 12–17 (38%) and young women aged 18–34 (45%) in South Africa. This study aimed to measure ...
Bosenberg, L.H.; Thomas, P.(In House Publications, 2022)
Cavernous transformation of the portal vein is a complication of a prior portal vein thrombosis and carries a very poor
prognosis. It is associated with portal hypertension, and the massive ascites that develops as a ...
Theron, Annette J.; Anderson, Ronald; Madzime, Morris; Rossouw, Theresa M.; Steel, Helen C.; Meyer, Pieter Willem Adriaan; Cholo, Moloko C.; Kwofie, Luyanda Laura Illicia; Feldman, Charles; Tintinger, Gregory(MDPI, 2022-12-19)
There is increasing awareness of an association between the uptake of the HIV integrase inhibitor,
dolutegravir, in first-line antiretroviral regimens with unusual weight gain and development
of the metabolic syndrome, ...
Stroke is a common and devastating event and the majority of cases are caused by thromboembolism from the left atrium, left ventricle or left sided valves. This case report describes a case of embolic stroke with the origin ...
AIMS :
To compare insulin dose adjustments made by physicians to those made by an artificial intelligence-based decision support system, the Advisor Pro, in people with type 1 diabetes (T1D) using an insulin pump and ...
Abdullah, Fareed; Myers, J.; Basu, Debashis; Tintinger, Gregory; Ueckermann, Veronica; Mathebula, M.; Ramlall, R.; Spoor, S.; De Villiers, T.; Van der Walt, Z.; Cloete, Jeane; Soma-Pillay, Priya; Rheeder, Paul; Paruk, Fathima; Engelbrecht, Adel; Lalloo, Vidya; Myburg, M.; Kistan, J.; Van Hougenhouck-Tulleken, W.G. (Wesley); Boswell, Michael T.; Gray, G.; Welch, R.; Blumberg, Lucille Hellen; Jassat, W.(Elsevier, 2022-03)
INTRODUCTION : The coronavirus disease 2019 (COVID-19) first reported in Wuhan, China in December 2019 is a global pandemic that is threatening the health and wellbeing of people worldwide. To date there have been more ...
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) variants of concern (VOCs) exhibit escape
from neutralizing antibodies, causing concern about vaccine effectiveness. However, while non-neutralizing
cytotoxic ...