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Browsing Theses and Dissertations (Immunology) by Type "Dissertation"
Now showing items 1-20 of 28
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(University of Pretoria, 2011)Infection with the human immunodeficiency virus (HIV) constitutes a global pandemic, and South Africa forms part of the region known to house over two-thirds of HIV infected individuals worldwide. In the early stages of ...
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(University of Pretoria, 2014)Background: Cancer is a crippling disease affecting 32.6 million people globally. It is currently ranked as the leading cause of death worldwide, and is associated with significant morbidity and mortality. Despite advances ...
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Bacterial translocation : cause of activated intestinal macrophages in decompensated liver disease (University of Pretoria, 2011)Background and Aim: Bacterial infections are a well described complication of cirrhosis and occur in 37% of hospitalized patients. Culture positive infections in addition to the presence of bacterial products and DNA ...
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(University of Pretoria, 2009-05-26)The one-way mixed lymphocyte culture (MLC) is used to assess histocompatibility between donor and recipient. First introduced in 1966, this method involves the co-culture of lymphocytes from the peripheral blood of the ...
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(University of Pretoria, 2022)The aim of this project was to develop assays that will allow for high-throughput screening to monitor adipogenesis. Such an assay may be useful for the identification of potential drug targets during the process of ...
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(University of Pretoria, 2023)The present study was undertaken with the initial objective of investigating the effects of six primary anti-pseudomonal antibiotics, namely amikacin, cefepime, ciprofloxacin, meropenem, piperacillin and tazobactam, on the ...
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(University of Pretoria, 2015)Introduction South Africa is ranked the third most obese country after the United States of America and Great Britain. According to a study conducted by the South African Medical Research Council, 61% of the South African ...
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(University of Pretoria, 2016)Background: Neutrophil extracellular traps (NETs) constitute a network of chromatin fibres containing histone and antimicrobial peptides that are released by activated neutrophils. NETs protect the host against infection ...
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(University of Pretoria, 2019)Streptococcus pneumoniae (the pneumococcus) is a Gram-positive bacterium that frequently colonises the nasopharynx of healthy humans. In susceptible hosts, especially children under 5 years with underdeveloped immune systems ...
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(University of Pretoria, 2011)Streptococcus pneumoniae is a common human pathogen, causing severe and often life-threatening respiratory tract infections. Even though most patients receive appropriate antimicrobial chemotherapy, a significant percentage ...
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(University of Pretoria, 2013)Chemotherapy of tuberculosis (TB), a disease caused by Mycobacterium tuberculosis (M. tuberculosis), is successful against actively-growing bacilli but ineffective against dormant/persistent organisms, found mainly in a ...
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(University of Pretoria, 2019)The dissertation describes the production and titration of molecular clones of HIV-1B and HIV-1C primary isolates, as well as the assessment of haematopoietic stem and progenitor cell function by colony-forming unit assay ...
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(University of Pretoria, 2013)The human leukocyte antigen (HLA) is the most polymorphic region in the human genome and accounts for more than 10% of human diversity. This region plays an important role in matching donors and recipients for transplantation. ...
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(University of Pretoria, 2010-08-03)Successful engraftment is highly dependent on the quality and quantity of stem cells and nucleated cells in cord blood. Storage of umbilical cord blood is expensive and it will be very useful if factors that influence cell ...
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(University of Pretoria, 2014)Persistent immune activation, even in the setting of virologically-suppressive HAART, is a hallmark of chronic immunodeficiency virus type (HIV-1) infection and a major force driving HIV-1 replication and progression to ...
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(University of Pretoria, 2006-08-19)The full text of this thesis/dissertation is not available online. Please <a href="mailto:upetd@up.ac.za">contact us</a> if you need access. Read the abstract in the section 00front of this document.
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(University of Pretoria, 2011)Although blood products are a great deal safer these days than in the past, patients receiving allogeneic blood transfusions are still exposed to potential hazards such as infectious diseases and immunomodulatory reactions. ...
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(University of Pretoria, 2022)The use of adipose-derived stromal/stem cells (ASCs) continues to increase in the field of regenerative medicine and other clinical applications. Adipose tissue can be collected in a less invasive procedure, when compared ...
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(University of Pretoria, 2009-12-09)A) Bariatric surgery for the treatment of obesity has shown much promise. The Roux-en-Y gastric bypass is a procedure that combines both restrictive and malabsorptive elements. Post-operative weight loss and co-morbidity ...
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(University of Pretoria, 2007-05-11)Moxifloxacin is considered to be a broad-spectrum fluoroquinolone due to its activity against both gram positive and gram negative bacteria. Importantly this agent is currently being evaluated in ongoing clinical trials ...
Now showing items 1-20 of 28