Browsing Theses and Dissertations (Immunology) by Subject "Health sciences theses SDG-10"

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Evaluating the effects of HIV-1 infection on haematopoietic stem cell colony formation

Herd, Candice Lee (University of Pretoria, 2019)

The dissertation describes the production and titration of molecular clones of HIV-1B and HIV-1C primary isolates, as well as the assessment of haematopoietic stem and progenitor cell function by colony-forming unit assay ...
Human leukocyte antigen (HLA) genetic diversity in South African populations

Tshabalala, Mqondisi (University of Pretoria, 2018)

There is documented evidence of high genetic diversity amongst African populations, but there is limited data on human leukocyte antigen (HLA) diversity in these populations. HLA genes are highly polymorphic, and encode ...
Optimisation of histocompatibility testing in living-donor renal transplantation

Kwofie, Luyanda Laura Illicia (University of Pretoria, 2018)

The study addressed the development and evaluation of novel procedures for the rapid, reproducible and efficient measurement of T cell alloreactivity both pre- and post-transplantation, with the aim of optimizing donor/ ...
Transcriptional analysis of the host response to HIV-1 infection in CD4+ T lymphocytes monocytes and macrophages

Wickham, Catherine Heather (University of Pretoria, 2019)

The human immunodeficiency virus (HIV) is the causative agent of acquired immune deficiency syndrome (AIDS), a condition characterized by depletion of CD4+ T cells and other immune system dysfunctions. Due to its widespread ...

Now showing items 1-4 of 4

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