AIM : Therapy with low-dose amitriptyline is commonly used to treat painful diabetic peripheral neuropathy. There is a knowledge gap, however, regarding the role of variable CYP2D6-mediated drug metabolism and side effects ...
Dodgen, Tyren Mark; Eloff, Arinda; Mataboge, C.K.; Roos, J.L. (Johannes Louw); Van Staden, C.W. (Werdie); Pepper, Michael Sean(Elsevier, 2015-04)
BACKGROUND : Contradictory information exists regarding the influence of CYP2D6 polymorphisms on adverse drug
reactions (ADRs) (extrapyramidal symptoms (EPS) and weight gain) related to risperidone treatment. This
prompted ...
