Browsing Research Articles (Pharmacology) by Subject "Glucose clamp"

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A practical guide to the interpretation of PK/PD profiles of longer-acting analogue insulins. Part one : the principles of glucose clamp studies

Greeff, Oppel Bernhardt Wilhelm; Van Tonder, Jacob John; Naidu, Kershlin; McMaster, Alicia; Van Tonder, Alet; Mothilal, Rashem (MedPharm Publications, 2018-02-12)

Glucose clamp studies are used to determine pharmacokinetics (PK) and pharmacodynamics (PD) of analogue insulins. With the development of longer-acting basal analogue insulins, including glargine 300 (Gla-300) and insulin ...
A practical guide to the interpretation of PK/PD profiles of longer-acting analogue insulins. Part two : insulin degludec vs. insulin glargine U300

Greeff, Oppel Bernhardt Wilhelm; Van Tonder, Jacob John; Naidu, Kershlin; McMaster, Alicia; Van Tonder, Alet; Mothilal, Rashem (MedPharm Publications, 2018)

Glucose clamp studies form an integral part of the early development of insulin therapies. Data generated in these studies are used to establish pharmacokinetic (PK) and pharmacodynamic (PD) profiles of the agents, but ...

Now showing items 1-2 of 2

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