Browsing Research Articles (Pharmacology) by Subject "Differentiation"

Now showing items 1-2 of 2

Proteomic comparison of various hepatic cell cultures for preclinical safety pharmacology

Hurrell, Tracey; Segeritz, Charis-Patricia; Vallier, Ludovic; Lilley, Kathryn S.; Cromarty, Allan Duncan (Oxford University Press, 2018-07)

Experimental drugs need to be screened for safety within time constraints. Hepatotoxicity is one concerning contributor to the failure of investigational new drugs and a major rationale for postmarketing withdrawal decisions. ...
A simplified workflow with end-point validation of real-time electrical cell-substrate impedance sensing of retinoic acid stimulated neurogenesis in human SH-SY5Y cells in vitro

Joos‑Vandewalle, Julia; Steenkamp, Vanessa; Prinsloo, Earl (BMC, 2023-06-01)

OBJECTIVE : Retinoic acid (RA) is known to transition proliferating SH-SY5Y neuroblastoma cells towards functional neurons. However, the activity of RA is restricted due to its photolability where any findings from prolonged ...

Now showing items 1-2 of 2

Search UPSpace