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Browsing Research Articles (Pharmacology) by Author "Van Tonder, Jacob John"
Now showing items 1-9 of 9
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Komolafe, Ayoola Oluwakayode; Ally, Mahmood Moosa Tar Mahomed; Van Tonder, Jacob John; Greeff, Oppel Bernhardt Wilhelm (Medpharm Publications, NISC (Pty) Ltd and Cogent, Taylor & Francis Group, 2015-01)The anti-inflammatory properties of statins are well documented. The aim of this study was to determine if statins may offer therapeutic benefits in rheumatoid arthritis (RA) patients that are also at risk for cardiovascular ...
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Schroeder, Ilka Elizma; Van Tonder, Jacob John; Steenkamp, Vanessa (Bentham Science, 2012)The organochlorine compound, pentachlorophenol (PCP), is classified as a hazardous substance. Its metabolite, tetrachloro-1,2-hydroquinone (TCHQ), has been detected in occupationally-exposed subjects and can readily be ...
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Steenkamp, Vanessa; Nkwane, O.; Van Tonder, Jacob John; Dinsmore, A.; Gulumian, Mary (Academic Journals, 2013-04-08)Warburgia salutaris (Bertol. F.) Chiovs, Rhoicissus tridentata (L.f.) Wild & Drum and Terminalia sericea (Burch. ex DC.), are widely used medicinal plants in southern Africa. The aim of the study was to determine the ...
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Van Tonder, Jacob John; Gulumian, Mary; Cromarty, Allan Duncan; Steenkamp, Vanessa (SAGE, 2014-01)The organochlorine pesticide, dichlorodiphenyltrichloroethane (DDT), is still used to combat the spread of malaria in several developing countries despite its accumulation and known hepatotoxic effects that have ...
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Seoposengwe, Keabetswe; Van Tonder, Jacob John; Steenkamp, Vanessa (BioMed Central, 2013-12-12)BACKGROUND: Lannea schweinfurthii, Zanthoxylum capense, Scadoxus puniceus and Crinum bulbispermum are used traditionally to treat neurological disorders. The aim of this study was to evaluate the cytoprotective potential ...
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Greeff, Oppel Bernhardt Wilhelm; Van Tonder, Jacob John; Cromarty, Allan Duncan; Lowman, Warren; Becker, Piet J.; Nell, Margo Judith (MedPharm Publications, 2015)INTRODUCTION : Teicoplanin is an effective treatment option against methicillin-resistant, Gram-positive bacteria, like Staphylococcus aureus. It is a glycopeptide antibiotic, produced through microbial fermentation, a ...
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Greeff, Oppel Bernhardt Wilhelm; Van Tonder, Jacob John; Naidu, Kershlin; McMaster, Alicia; Van Tonder, Alet; Mothilal, Rashem (MedPharm Publications, 2018-02-12)Glucose clamp studies are used to determine pharmacokinetics (PK) and pharmacodynamics (PD) of analogue insulins. With the development of longer-acting basal analogue insulins, including glargine 300 (Gla-300) and insulin ...
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Greeff, Oppel Bernhardt Wilhelm; Van Tonder, Jacob John; Naidu, Kershlin; McMaster, Alicia; Van Tonder, Alet; Mothilal, Rashem (MedPharm Publications, 2018)Glucose clamp studies form an integral part of the early development of insulin therapies. Data generated in these studies are used to establish pharmacokinetic (PK) and pharmacodynamic (PD) profiles of the agents, but ...
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Mer, Mervyn; Snyman, Jacques Rene; Jansen van Rensburg, Elizabeth; Van Tonder, Jacob John; Laurens, Ilze (Dove Medical Press, 2016-11-17)INTRODUCTION : Clinicians’ skepticism, fueled by evidence of inferiority of some multisource generic antimicrobial products, results in the underutilization of more cost-effective generics, especially in critically ill ...
Now showing items 1-9 of 9