Van Tonder, Alet; Joubert, Annie M.; Cromarty, Allan Duncan(BioMed Central, 2013-02-20)
BACKGROUND : The tetrazolium-based MTT assay has long been regarded as the gold standard of cytotoxicity assays as it is highly sensitive and has been miniaturised for use as a high-throughput screening assay. However, ...
Greeff, Oppel Bernhardt Wilhelm; Van Tonder, Jacob John; Naidu, Kershlin; McMaster, Alicia; Van Tonder, Alet; Mothilal, Rashem(MedPharm Publications, 2018-02-12)
Glucose clamp studies are used to determine pharmacokinetics (PK) and pharmacodynamics (PD) of analogue insulins. With the
development of longer-acting basal analogue insulins, including glargine 300 (Gla-300) and insulin ...
Greeff, Oppel Bernhardt Wilhelm; Van Tonder, Jacob John; Naidu, Kershlin; McMaster, Alicia; Van Tonder, Alet; Mothilal, Rashem(MedPharm Publications, 2018)
Glucose clamp studies form an integral part of the early development of insulin therapies. Data generated in these studies
are used to establish pharmacokinetic (PK) and pharmacodynamic (PD) profiles of the agents, but ...
