Browsing Internal Medicine by Title

Browsing Internal Medicine by Title

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  • Journal clubs - knowledge sufficient for critical appraisal of the literature? 
    Rheeder, Paul; Van Zyl, Danie G.; Webb, Elize M.; Worku, Zeleke (South African Medical Association, 2007-03)
    Sir James Paget, reflecting on his experiences at St Bartholomew’s Hospital in London during 1835 - 1854, noted: ‘Some of the self-select of the pupils, making themselves into a kind of club, had a small room over a baker’s ...
  • Knowledge of foot care in people with diabetes in a tertiary care setting 
    Rheeder, Paul; Venn, Marie; De Korte, Ewald; Van Zyl, Danie G. (Health and Medical Publishing Group, 2008-12)
    BACKGROUND: The objective of this study was to investigate levels of foot care knowledge among patients attending the diabetes clinic at Pretoria Academic Hospital by comparing the knowledge of patients with ‘at risk’ feet ...
  • Late-onset efavirenz toxicity : a descriptive study from Pretoria, South Africa 
    Munsami, Lyneshree; Schutte, Clara-Maria; De Villiers, Maryke; Hiesgen, Juliane (AOSIS, 2023-01-19)
    BACKGROUND : The neuropsychiatric side effects of efavirenz occur mainly early during treatment and are usually mild. A lesser-known and serious complication is late-onset efavirenz toxicity causing ataxia and encephalopathy. ...
  • LDL-cholesterol reduction vs LDL target level : which is more important? 
    Ker, James A. (New Media Publishing, 2016-07)
    There is enough documented evidence of the role of low-density-lipoprotein cholesterol (LDL-C) in the pathogenesis of atherosclerotic cardiovascular disease (CVD).
  • Lipid accumulation and alkaline phosphatase activity in human preadipocytes isolated from different body fat depots 
    Ali, A.T.; Ferris, W.F.; Penny, C.B.; Van der Merwe, Maria-Teresa; Jacobson, B.F.; Paiker, J.E.; Crowther, Nigel J. (Health and Medical Publishing Group, 2013-05)
    BACKGROUND: Alkaline phosphatase (ALP) controls intracellular lipid accumulation in human preadipocytes, but it is not known whether ALP is expressed in all body fat depots, or whether it has a similar role at all ...
  • Lower limb pain syndromes 
    Ally, Mahmood Moosa Tar Mahomed; Suleman, Farhana Ebrahim (Health and Medical Publishing Group, 2011-08)
    Lower limb pain is a common presenting complaint in primary care with aetiological factors such as trauma, repetitive strain injury and systemic inflammatory disorders. This review focuses on some commonly encountered ...
  • Lymphopenia and IgG2 subclass deficiency in patients with severe COVID-19 pneumonia 
    Taban, E.M.; Tintinger, Gregory Ronald; Joseph, Darren; Gaylard. P.; Richards, D. (South African Medical Association NPC, 2021-03-29)
    BACKGROUND : COVID-19 caused by the novel severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) manifests with a range of disease severities. A small proportion of COVID-19 patients are severely ill; however, a ...
  • Making the case for an obstetric medicine subspecialty in South Africa 
    Zamparini, J; Wium, Lizemarie (Health and Medical Publishing Group, 2020-12)
    Obstetric medicine is a subspecialty of internal medicine that involves the management of medical conditions that may affect the course of pregnancy. It is an established subspecialty in many parts of the world, with ...
  • Management issues in hypertensive diabetics 
    Ker, James A. (2006-11)
    This article discusses seven issues in the management of hypertension in diabetic patients, namely the importance of blood pressure control, optimal blood pressure control levels, the importance of blocking the renin-angiotensin ...
  • The management of acute low back pain in adults : a guide for the primary care physician 
    Brighton, S.W. (South African Academy of Family Practice/Primary Care, 2012)
    To diagnose patients with acute low back pain (LBP), a focused physical examination needs to be conducted and a detailed history obtained. The patient should then be placed into one of three broad categories, namely ...
  • The management of acute low back pain in adults : a guide for the primary care physician, Part II 
    Brighton, S.W. (South African Academy of Family Practice/Primary Care, 2013-01)
    When a patient presents with acute low back pain (LBP), any red flag warnings of serious disease should first be excluded. Yellow and blue flag warnings of psychological factors should be noted. A psychological opinion of ...
  • Mechanical ventilation in the emergency department 
    Engelbrecht, Andreas; Tintinger, Gregory Ronald (Health and Medical Publishing Group, 2007-03)
    An increasing number of critically ill patients need to be managed in emergency departments worldwide. Numerous theories have attempted to explain the growing number of critically ill patients presenting to emergency ...
  • The mechanism of action of oral antidiabetic drugs : a review of recent literature 
    Bosenberg, Liesel H.; Van Zyl, Danie G. (Health & Medical Publishing Group, 2008-12)
    Type 2 diabetes mellitus (DM) is a disorder that is placing an increasing burden on health service delivery worldwide. Consequently, it has become increasingly important that physicians who treat such patients have a good ...
  • Metabolic surgery : a concise overview and understanding of potential complications 
    Potgieter, A.J.; Van der Merwe, Maria-Teresa (Health and Medical Publishing Group, 2011)
    Bariatric surgery, despite a relatively short history, has had a tremendous impact on the discipline of surgery. In addition, it has had a profound influence on the development of laparoscopic surgery and the treatment ...
  • Metabolic syndrome indicators and target organ damage in urban active coping African and Caucasian men : the SABPA study 
    De Kock, A.; Malan, Leone; Potgieter, Johan C.; Steenekamp, Wilme; Van der Merwe, Maria-Teresa (Thieme Publishing, 2012)
    Psychosocial stress relating to an urban environment or acculturation increases the prevalence of metabolic syndrome (MetS). The objectives of this study were firstly to indicate and compare differences regarding appraisal ...
  • Metabolomics of colistin methanesulfonate treated Mycobacterium tuberculosis 
    Koen, Nadia; Van Breda, Shane Vontelin; Loots, Du Toit (Elsevier, 2018-07)
    Over the past 5 years, there has been a renewed interest in finding new compounds with anti-TB action. Colistin methanesulfonate or polymyxin E, is a possible anti-TB drug candidate, which may in future be used either alone ...
  • MI management considerations in the elderly 
    Ker, James A. (New Media Publishing, 2019-04)
    One of the acknowledged problems is that the elderly has not been represented enough in randomised clinical trials of myocardial infarction (MI) management. Now, 40 years since the first percutaneous coronary ...
  • MicroRNA profiling in HIV-infected South African women with gestational diabetes mellitus 
    Pheiffer, Carmen; Dias, Stephanie Charmaine; Rheeder, Paul; Adam, Sumaiya (Springer, 2019-08)
    BACKGROUND : Recently, we reported that the microRNAs (miRNAs) miR-20a-5p and—to a lesser extent—miR-222-3p hold potential as biomarkers for gestational diabetes mellitus (GDM) in human immunodeficiency virus (HIV)-negative ...
  • Mitotic syndicates Aurora Kinase B (AURKB) and mitotic arrest deficient 2 like 2 (MAD2L2) in cohorts of DNA damage response (DDR) and tumorigenesis 
    Marima, Rahaba; Hull, Rodney; Penny, Clement; Dlamini, Zodwa (Elsevier, 2021-01)
    Aurora Kinase B (AURKB) and Mitotic Arrest Deficient 2 Like 2 (MAD2L2) are emerging anticancer therapeutic targets. AURKB and MAD2L2 are the least well studied members of their protein families, compared to AURKA and ...
  • The MOGE(S) system explained 
    Ker, James A. (Media 24, 2015-08)
    In a standard textbook of medicine, the first step in the evaluation of cardiomyopathy is to make the distinction between ischaemic heart disease (IHD) as the cause of cardiomyopathy as opposed to nonischaemic causes of ...