The mechanism of action of oral antidiabetic drugs : a review of recent literature
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Date
Authors
Bosenberg, Liesel H.
Van Zyl, Danie G.
Journal Title
Journal ISSN
Volume Title
Publisher
Health & Medical Publishing Group
Abstract
Type 2 diabetes mellitus (DM) is a disorder that is placing an increasing burden on health service delivery worldwide. Consequently, it has become increasingly important that physicians who treat such patients have a good knowledge of antidiabetic drugs that are currently available or will come onto the market. This article presents an overview of all the major drug classes as well as some information on pharmacokinetics, pharmacodynamics, side-effect profiles and indications for use.
Description
Keywords
Antidiabetic drugs, Oral drugs, Type 2 diabetes mellitus, Physician's knowledge, Drug knowledge, Drug mechanism, Pharmacokinetics, Pharmacodynamics, Side effects, Literature review, Insulin secretagogues, Sulfonylureas, Glibenclamide, Gliclazide, Glipizide, Glimepiride, Rapid-acting prandial insulin, Repaglinide, Nateglinide, Insulin releasers, Insulin sensitisers, Biguanides, Metformin, Thiazolidinediones, Pioglitazone, Rosiglitazone, Glucosidase inhibitors, Acarbose, Incretins, Exendin-4, Liraglutide, Vildagliptin, Sitagliptin, Amylin analogues, Pramlintide, Treatment modalities
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Citation
Bosenberg, LH & Van Zyl, DG 2008, 'The mechanism of action of oral antidiabetic drugs: a review of recent literature', Journal of Endocrinology, Metabolism and Diabetes of South Africa, vol. 13, no. 3, pp. 80-88. [http://www.hmpg.co.za/journaldetail.php?journalno=9]