The mechanism of action of oral antidiabetic drugs : a review of recent literature

dc.contributor.authorBosenberg, Liesel H.
dc.contributor.authorVan Zyl, Danie G.
dc.contributor.emaildanie.vanzyl@up.ac.zaen_US
dc.date.accessioned2009-05-25T09:31:57Z
dc.date.available2009-05-25T09:31:57Z
dc.date.issued2008-12
dc.description.abstractType 2 diabetes mellitus (DM) is a disorder that is placing an increasing burden on health service delivery worldwide. Consequently, it has become increasingly important that physicians who treat such patients have a good knowledge of antidiabetic drugs that are currently available or will come onto the market. This article presents an overview of all the major drug classes as well as some information on pharmacokinetics, pharmacodynamics, side-effect profiles and indications for use.en_US
dc.identifier.citationBosenberg, LH & Van Zyl, DG 2008, 'The mechanism of action of oral antidiabetic drugs: a review of recent literature', Journal of Endocrinology, Metabolism and Diabetes of South Africa, vol. 13, no. 3, pp. 80-88. [http://www.hmpg.co.za/journaldetail.php?journalno=9]en_US
dc.identifier.issn1608-9677
dc.identifier.urihttp://hdl.handle.net/2263/10139
dc.language.isoenen_US
dc.publisherHealth & Medical Publishing Groupen_US
dc.rightsHealth & Medical Publishing Groupen_US
dc.subjectAntidiabetic drugsen_US
dc.subjectOral drugsen_US
dc.subjectType 2 diabetes mellitusen_US
dc.subjectPhysician's knowledgeen_US
dc.subjectDrug knowledgeen_US
dc.subjectDrug mechanismen_US
dc.subjectPharmacokineticsen_US
dc.subjectPharmacodynamicsen_US
dc.subjectSide effectsen_US
dc.subjectLiterature reviewen_US
dc.subjectInsulin secretagoguesen_US
dc.subjectSulfonylureasen_US
dc.subjectGlibenclamideen_US
dc.subjectGliclazideen_US
dc.subjectGlipizideen_US
dc.subjectGlimepirideen_US
dc.subjectRapid-acting prandial insulinen_US
dc.subjectRepaglinideen_US
dc.subjectNateglinideen_US
dc.subjectInsulin releasersen_US
dc.subjectInsulin sensitisersen_US
dc.subjectBiguanidesen_US
dc.subjectMetforminen_US
dc.subjectThiazolidinedionesen_US
dc.subjectPioglitazoneen_US
dc.subjectRosiglitazoneen_US
dc.subjectGlucosidase inhibitorsen_US
dc.subjectAcarboseen_US
dc.subjectIncretinsen_US
dc.subjectExendin-4en_US
dc.subjectLiraglutideen_US
dc.subjectVildagliptinen_US
dc.subjectSitagliptinen_US
dc.subjectAmylin analoguesen_US
dc.subjectPramlintideen_US
dc.subjectTreatment modalitiesen_US
dc.subject.lcshDiabetics
dc.subject.lcshTherapeutics
dc.subject.lcshPharmacokinetics
dc.subject.lcshDrugs -- Physiological effect
dc.subject.meshDiabetes Mellitus, Type 2
dc.titleThe mechanism of action of oral antidiabetic drugs : a review of recent literatureen_US
dc.typeArticleen_US

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