Browsing Internal Medicine by Title

Browsing Internal Medicine by Title

Sort by: Order: Results:

  • Global DNA methylation profiling in peripheral blood cells of South African women with gestational diabetes mellitus 
    Dias, Stephanie Charmaine; Adam, Sumaiya; Van Wyk, Nastasja; Rheeder, Paul; Louw, Johan; Pheiffer, Carmen (Taylor and Francis, 2019)
    BACKGROUND/OBJECTIVE : Recently, several studies have reported that DNA methylation changes in tissue are reflected in blood, sparking interest in the potential use of global DNA methylation as a biomarker for gestational ...
  • The global impact of hypertension 
    Ker, James A. (New Media Publishing, 2016-03)
    It is estimated that hypertension is the cause of about 50% of heart disease, stroke and heart failure (HF), 18% of deaths overall and more than 40% of deaths in people with diabetes. In addition, hypertension is a leading ...
  • Glycaemic control improves fibrin network characteristics in type 2 diabetes : a purified fibrinogen model 
    Pieters, Marlien; Covic, Namukolo; Van der Westhuizen, Francois Hendrikus; Nagaswami, Chandrasekaran; Baras, Yelena; Loots, Du Toit; Jerling, Johann C.; Elgar, Dale; Edmondson, Kathryn S.; Van Zyl, Danie G.; Rheeder, Paul; Weisel, John W. (Schattauer, 2008-04)
    Diabetic subjects have been shown to have altered fibrin network structures.One proposed mechanism for this is non-enzymatic glycation of fibrinogen due to high blood glucose.We investigated whether glycaemic control would ...
  • Glycation of fibrinogen in uncontrolled diabetic patients and the effects of glycaemic control on fibrinogen glycation 
    Pieters, Marlien; Van Zyl, Danie G.; Rheeder, Paul; Jerling, Johann C.; Loots, Du Toit; Van der Westhuizen, Francois Hendrikus; Gottsche, Louise T.; Weisel, John W. (Elsevier, 2007)
    Evidence exists for a relationship between glycaemic control and macrovascular disease. Non-enzymatic glycation of proteins may explain this relationship in part. We investigated the effect of blood glucose control, under ...
  • HCV genotype 5 : epidemiology and spread of an uncommon genotype 
    Verbeeck, J.; Peigue-Lafeuille, H.; Ross, R.S.; Abergel, A.; Nevens, Frederik; Van der Merwe, Schalk Willem; Van Ranst, Marc; Henquell, C. (Elsevier, 2008-02)
  • Healthcare delivery 
    Schneider, H.; Kredo, T.; Odendaal, W.A.; Abdullah, Fareed (South African Medical Association, 2023-02)
    We report here on the process and findings of a research prioritisation exercise for universal health coverage (UHC) in South Africa, conducted during the course of 2019. As plans to roll out National Health Insurance ...
  • Heart failure 
    Ker, James A. (Medpharm Publications, 2010-05)
    Heart failure is a clinical syndrome that can result from any structural or functional cardiac disorder that impairs the performance of the ventricle: either to eject blood (systolic dysfunction) [or reduced ejection ...
  • The heart in diabetes 
    Ker, James A. (Clinics Cardiv, 2010-06)
    Diabetes mellitus is associated with a two- to four-fold increased risk of coronary artery disease, and in diabetic people, about two-thirds of deaths are cardiovascular (ischaemic heart disease, congestive heart failure ...
  • High risk exposure to HIV among sexually active individuals who tested negative on rapid HIV tests in the Tshwane District of South Africa—the importance of behavioural prevention measures 
    Mayaphi, Simnikiwe Horatious; Martin, Desmond J.; Olorunju, Steve A.S.; Williams, Brian G.; Quinn, Thomas C.; Stoltz, Anton Carel (Public Library of Science, 2018-02-02)
    OBJECTIVE : To assess the prevalence of HIV risk behaviour among sexually active HIV sero-negative individuals in the Tshwane district of South Africa (SA). METHODS : Demographic and HIV risk behaviour data were collected ...
  • Higher protein intake reduce risk of hypertension 
    Ker, James A. (New Media Publishing, 2015-11)
    Hypertension remains the most important treatable risk factor for cardiac disease worldwide.In the Dietary Approaches to Stop Hypertension (DASH) trials the importance of diet patterns to reduce blood pressure (BP), were shown.
  • HIV care coverage among HIV-positive adolescent girls and young women in South Africa: Results from the HERStory Study 
    Mathews, C.; Cheyip, M.; Beauclair, R.; Puren, A.; Lombard, C.; Jonas, K.; Ayalew, K.A.; Govindasamy, D.; Kuo, C.; Dietrich, J.; Abdullah, Fareed; Gray, G. (Health and Medical Publishing Group, 2021-05)
    BACKGROUND. Health service coverage cascades measure the proportion of a population in need of a service that experienced a positive health outcome from the service, and enable tracking of progress in achieving universal ...
  • Horizontal versus familial transmission of Helicobacter pylori 
    Schwarz, Sandra; Morelli, Giovanna; Manica, Andrea; Balloux, Francois; Owen, Robert J.; Graham, David Y.; Van der Merwe, Schalk Willem; Achtman, Mark; Suerbaum, Sebastian; Kusecek, Barica (Public Library of Science, 2008-10)
    Transmission of Helicobacter pylori is thought to occur mainly during childhood, and predominantly within families. However, due to the difficulty of obtaining H. pylori isolates from large population samples and to the ...
  • Human immunodeficiency virus infection and inflammatory arthritis : a review of clinical and imaging features 
    Suleman, Farhana Ebrahim; Ally, Mahmood Moosa Tar Mahomed (AOSIS OpenJournals, 2017-11-14)
    The reported prevalence of articular manifestations of human immunodeficiency virus (HIV) varies, but with sub-Saharan Africa accounting for almost 70% of the people living with HIV, this results in a considerable burden ...
  • Human skin volatiles : passive sampling and GC × GC-ToFMS analysis as a tool to investigate the skin microbiome and interactions with anthropophilic mosquito disease vectors 
    Roodt, A.P. (Alexis); Naude, Yvette; Stoltz, Anton Carel; Rohwer, Egmont Richard (Elsevier, 2018-10)
    Volatile organic compounds (VOCs) emanating from the surfaces of human skin are of great interest to researchers in medical and forensic fields, as well as to biologists studying the ecology of blood-feeding insect vectors ...
  • Hypercholesterolaemia and coronary risk 
    Ker, James A. (New Media Publishing, 2016-05)
    Studies have shown that only 10.6% of people with hypercholesterolaemia receive a statin or treatment. There is a within-person variability of cholesterol measurements and therefore a one-time measurement of cholesterol ...
  • Hypertension 
    Ker, James A. (South African Academy of Family Practice/Primary Care, 2011-07)
    Approximately one in four adults has hypertension, a prevalence that increases with age and may reach to two out of three adults older than 70 years of age. In the Framingham Heart Study 65-75% of hypertension in the elderly ...
  • Hypertension and sexual dysfunction 
    Ker, James A. (South African Academy of Family Practice/Primary Care, 2012)
    No abstract available.
  • Identification of a subgroup of black South Africans with type 1 diabetes who are older at diagnosis but have lower levels of glutamic acid decarboxylase and islet antigen 2 autoantibodies 
    Padoa, Carolyn J.; Rheeder, Paul; Pirie, Fraser J.; Motala, Ayesha A.; Van Dyk, Jacobus C.; Crowther, Nigel J. (Wiley, 2020-12)
    AIMS : To compare the age at diagnosis and prevalence of islet autoantibody [glutamic acid decarboxylase (65 kDa) 65 and islet antigen 2] positivity in black and white participants with type 1 diabetes in South Africa, and ...
  • Impact of CYP2D6 genotype on amitriptyline efficacy for the treatment of diabetic peripheral neuropathy : a pilot study 
    Chaudhry, Mamoonah; Alessandrini, Marco; Rademan, Jacobus; Dodgen, Tyren Mark; Steffens, Francois E.; Van Zyl, Danie G.; Gaedigk, Andrea; Pepper, Michael Sean (Future Medicine, 2017-03)
    AIM : Therapy with low-dose amitriptyline is commonly used to treat painful diabetic peripheral neuropathy. There is a knowledge gap, however, regarding the role of variable CYP2D6-mediated drug metabolism and side effects ...
  • Impact of FDG PET on the management of TBC treatment 
    Sathekge, Mike Machaba; Maes, Alex; Kgomo, Mbo; Stoltz, Anton Carel; Pottel, Hans; Van de Wiele, Christophe (Schattauer, 2010)
    The AIM: of this study is to assess the potential impact of double-phase FDG PET versus routine staging in HIV-negative patients suffering from tuberculosis. PATIENTS, METHODS: 16 consecutive patients suffering from ...