Browsing Research Articles (Nuclear Medicine) by Title

Browsing Research Articles (Nuclear Medicine) by Title

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  • 18F-FDG PET/CT as a noninvasive biomarker for assessing adequacy of treatment and predicting relapse in patients treated for pulmonary tuberculosis 
    Lawal, Ismaheel Opeyemi; Fourie, Bernard P.; Mathebula, Matsontso; Moagi, Ingrid; Lengana, Thabo; Moeketsi, Nontando; Nchabeleng, Maphoshane; Hatherill, Mark; Sathekge, Mike Machaba (Society of Nuclear Medicine, 2020-03)
    Microbial culture is the gold standard for determining the effectiveness of tuberculosis treatment. End-of-treatment (EOT) 18F-FDG PET/CT findings are variable among patients with negative microbial culture results after ...
  • 18F-FDG-PET/CT imaging of uterine cervical cancer recurrence in women with and without HIV infection 
    Lawal, Ismaheel Opeyemi; Ololade, Kehinde; Popoola, Gbenga O.; Ankrah, Alfred O.; Vorster, Mariza; Maes, Alex; Mokgoro, N.P. (Neo); Van de Wiele, Christophe; Sathekge, Mike Machaba (Edizioni Minerva Medica, 2022-03)
    BACKGROUND : To compare the rate, time and, pattern of recurrence of cervical cancer between patients with and without HIV infection and to determine factors predicting cervical cancer recurrence in patients evaluated by ...
  • 213Bi-PSMA-617 targeted alpha-radionuclide therapy in metastatic castration-resistant prostate cancer 
    Sathekge, Mike Machaba; Knoesen, Otto; Meckel, Marian; Modiselle, Moshe; Vorster, Mariza; Marx, Sebastian (Springer, 2017-06)
    Prostate-specific membrane antigen radioligand therapy (PSMA-RLT) with 177Lu-PSMA holds great promise as a safe treatment option in patients with metastasized castration-resistant prostate cancer (mCRPC) with ...
  • 225Ac-PSMA-617 in chemotherapy-naive patients with advanced prostate cancer : a pilot study 
    Sathekge, Mike Machaba; Bruchertseifer, Frank; Knoesen, Otto; Reyneke, Florette; Lawal, Ismaheel Opeyemi; Lengana, Thabo; Davis, Cindy; Mahapane, Johncy; Corbett, Ceceila; Vorster, Mariza; Morgenstern, Alfred (Springer, 2019-01)
    BACKGROUND : A remarkable therapeutic efficacy has been demonstrated with 225Ac-prostate-specific membrane antigen (PSMA)- 617 in heavily pre-treated metastatic castration-resistant prostate cancer (mCRPC) patients.We ...
  • 225Ac-PSMA-617 radioligand therapy of de novo metastatic hormone-sensitive prostate carcinoma (mHSPC): preliminary clinical findings 
    Sathekge, Mike Machaba; Bruchertseifer, Frank; Vorster, Mariza; Lawal, Ismaheel Opeyemi; Mokoala, K.M.G. (Kgomotso); Reed, Janet D.; Maserumule, Letjie; Ndlovu, Honest; Hlongwa, Khanyi; Maes, Alex; Morgenstern, Alfred; Van de Wiele, Christophe (Springer, 2023-06)
    PURPOSE : 225Ac-PSMA-617 has demonstrated good anti-tumor effect as a treatment option for metastatic castration-resistant prostate cancer (mCRPC) patients. No study has previously assessed treatment outcome and survival ...
  • [68 Ga]Ga-FAPI versus [18F]F-FDG in malignant melanoma: complementary or counterpoint? 
    Mokoala, K.M.G. (Kgomotso); Emil, Novruzov; Lawal, Ismaheel Opeyemi; Antke, Christina; Giesel, Frederik L.; Sathekge, Mike Machaba (Springer, 2022-06)
    No abstract available.
  • 68Ga-FAPI-PET/CT in patients with various gynecological malignancies 
    Dendl, Katharina; Koerber, Stefan A.; Finck, Rebecca; Mokoala, K.M.G. (Kgomotso); Staudinger, Fabian; Schillings, Lisa; Heger, Ulrike; Rohrich, Manuel; Kratochwil, Clemens; Sathekge, Mike Machaba; Jager, Dirk; Debus, Jurgen; Haberkorn, Uwe; Giesel, Frederik L. (Springer, 2021-11)
    PURPOSE : 68Ga-FAPI (fibroblast activation protein inhibitor) is a novel and highly promising radiotracer for PET/CT imaging. The aim of this retrospective analysis is to explore the potential of FAPI-PET/CT in gynecological ...
  • 68Ga-nitroimidazole PET/CT imaging of hypoxia in tuberculosis : a case series 
    Bresser, Philppa Lynn; Reed, Janet D.; Sathekge, Mike Machaba; Vorster, Mariza (Wiley Open Access, 2022-12)
    Tuberculosis (TB) lesions in humans have been proven to be severely hypoxic with hypoxia leading to latency and dormancy of disease. Dormant TB lesions become less susceptible to standard TB treatment regimens with varying ...
  • 68Ga-PSMA-11 PET/CT in primary staging of prostate carcinoma : preliminary results on differences between black and white South-Africans 
    Sathekge, Mike Machaba; Lengana, Thabo; Maes, Alex; Vorster, Mariza; Zeevaart, Jan Rijn; Lawal, Ismaheel Opeyemi; Ebenhan, Thomas; Van de Wiele, Christophe (Springer, 2018-02)
    PURPOSE : The incidence of prostate cancer is 60% higher and the mortality rate is two- to three-times greater in black versus white men. We report on differences in 68Ga-PSMA-11 PET/CT imaging findings in 77 black ...
  • 68Ga-PSMA-HBED-CC PET imaging in breast carcinoma patients 
    Sathekge, Mike Machaba; Lengana, Thabo; Modiselle, Moshe; Vorster, Mariza; Zeevaart, Jan Rijn; Maes, Alex; Ebenhan, Thomas; Van de Wiele, Christophe (Springer, 2017-04)
    BACKGROUND : To report on imaging findings using 68Ga-PSMAHBED- CC PET in a series of 19 breast carcinoma patients. METHODS : 68Ga-PSMA-HBED-CC PET imaging results obtained were compared to routinely performed staging ...
  • [68Ga]Ga-NODAGAZOL uptake in atherosclerotic plaques correlates with the cardiovascular risk profile of patients 
    Ndlovu, Honest; Lawal, Ismaheel Opeyemi; Popoola, Gbenga O.; Brits, Bradley; Mokoala, K.M.G. (Kgomotso); Maserumule, Letjie; Hlongwa, K.; Mahapane, Johncy; Davis, Cindy; Sathekge, Mike Machaba (Springer, 2022-07)
    Please read abstract in the article.
  • [68ga]ga-pentixafor for pet imaging of vascular expression of cxcr-4 as a marker of arterial inflammation in hiv-infected patients : a comparison with18f[fdg] pet imaging 
    Lawal, Ismaheel Opeyemi; Popoola, Gbenga O.; Mahapane, Johncy; Kaufmann, Jens; Davis, Cindy; Ndlovu, Honest; Maserumule, L.C. (Letjie); Mokoala, K.M.G. (Kgomotso); Bouterfa, Hakim; Wester, Hans-Jurgen; Zeevaart, Jan Rijn; Sathekge, Mike Machaba (MDPI, 2020-12)
    People living with human immunodeficiency virus (PLHIV) have excess risk of atherosclerotic cardiovascular disease (ASCVD). Arterial inflammation is the hallmark of atherogenesis and its complications. In this study we ...
  • 89Zr-Leukocyte labelling for cell trafficking : in vitro and preclinical investigations 
    Kahts, Maryke; Guo, Hua; Kommidi, Harikrishna; Yang, Yanping; Sayman, Haluk Burcak; Summers, Beverley; Ting, Richard; Zeevaart, Jan Rijn; Sathekge, Mike Machaba; Aras, Omer (SpringerOpen, 2023-11-06)
    BACKGROUND : The non-invasive imaging of leukocyte trafficking to assess inflammatory areas and monitor immunotherapy is currently generating great interest. There is a need to develop more robust cell labelling and ...
  • Aberrant vascular anatomy associated with artifactual focal avidity in the liver on PSMA PET 
    Lawal, Ismaheel Opeyemi; Pectasides, Melina; Parihar, Ashwin Singh; Shah, Hardik U.; Halkar, Raghuveer K.; Jani, Ashesh B.; Schuster, David M. (Lippincott Williams and Wilkins, 2023-09)
    68Ga–prostate-specific membrane antigen (PSMA) PET/CT is a valuable tool for staging and restaging of prostate cancer. Prostate-specific membrane antigen expression is not specific to prostate cancer, as it is expressed ...
  • Accuracy of bone SPECT/CT for identifying hardware loosening in patients who underwent lumbar fusion with pedicle screws 
    Hudyana, Hendrah; Maes, Alex; Vandenberghe, Thierry; Fidlers, Luc; Sathekge, Mike Machaba; Nicolai, Daniel; Van de Wiele, Christophe (Springer, 2016-02)
    BACKGROUND : The aim of this retrospective study was to evaluate the accuracy of bone SPECT (single photon emission computed tomography)/CT (computed tomography) in diagnosing loosening of fixation material in patients ...
  • The added value of [F-18]FDG PET/CT in the management of invasive fungal infections 
    Ankrah, Alfred O.; Creemers-Schild, Dina; De Keizer, Bart; Klein, Hans C.; Dierckx, Rudi A.J.O.; Kwee, Thomas C.; Span, Lambert F.R.; De Jong, Pim A.; Sathekge, Mike Machaba; Glaudemans, Andor W.J.M. (MDPI, 2021-01-17)
    Anatomy-based imaging methods are the usual imaging methods used in assessing invasive fungal infections (IFIs). [18F]FDG PET/CT has also been used in the evaluation of IFIs. We assessed the added value of [18F]FDG PET/CT ...
  • Adjunctive use of statins for COVID-19 
    Sathekge, Mike Machaba; Byttebier, Geert; De Spiegeleer, Bart; Saxberg, Bo; Ueckermann, Veronica; Belmans, Luc; Alexander, Myriam; Fedson, David (MDPI, 2021-04-01)
    The interaction between obesity, cardiometabolic disorders and COVID-19 represents a syndemic that requires both social intervention and a multipharmacological approach. The risks associated with diabetes, obesity and ...
  • Advances in imaging of tuberculosis: the role of 18 F-FDG PET and PET/CT 
    Vorster, Mariza; Sathekge, Mike Machaba; Bomanji, Jamshed (Lippincott Williams and Wilkins, 2014-05)
    PURPOSE OF REVIEW : To review the main applications, advantages and limitations of 18F-FDG PET and PET/computed tomography (CT), and some other tracers in imaging of tuberculosis (TB). RECENT FINDINGS : In pulmonary TB, ...
  • Advances in radioligand theranostics in oncology 
    Lawal, Ismaheel Opeyemi; Abubakar, Sofiullah O.; Ndlovu, Honest; Mokoala, Kgomotso M.G.; More, Stuart; Sathekge, Mike Machaba (Springer, 2024-05)
    Please read abstract in the article.
  • Analytical characterization of NOTA-modified somatropins 
    Bracke, Nathalie; Wynendaele, Evelien; D’Hondt, Matthias; Haselberg, Rob; Somsen, Govert W.; Pauwels, Ewald; Van de Wiele, Christophe; De Spiegeleer, Bart (Elsevier, 2014-08)
    Chemical modification of biomolecules like the introduction of metal-chelators into proteins can lead to heterogeneous product formation. The nature and extend of the modification is important in interpreting the biological ...