• Highlighting new research trends on Zirconium-89 radiopharmaceuticals beyond antibodies 

  Duvenhage, Janie; Kahts, Maryke; Summers, Beverley; Zeevaart, Jan Rijn; Ebenhan, Thomas (Elsevier, 2024-11)

  Please read abstract in the article.
• Prostate-specific membrane antigen-positron emission tomography-guided radiomics and machine learning in prostate carcinoma 

  Maes, Justine; Gesquière, Simon; Maes, Alex; Sathekge, Mike Machaba; Van de Wiele, Christophe (MDPI, 2024-10)

  Positron emission tomography (PET) using radiolabeled prostate-specific membrane antigen targeting PET-imaging agents has been increasingly used over the past decade for imaging and directing prostate carcinoma treatment. ...
• Radiotherapy and theranostics : a Lancet Oncology Commission 

  Abdel-Wahab, May; Giammarile, Francesco; Carrara, Mauro; Paez, Diana; Hricak, Hedvig; Ayati, Nayyereh; Li, Jing Jing; Mueller, Malina; Aggarwal, Ajay; Al-Ibraheem, Akram; Alkhatib, Sondos; Atun, Rifat; Bello, Abubakar; Berger, Daniel; Delgado Bolton, Roberto C.; Buatti, John M.; Burt, Graeme; Bjelac, Olivera Ciraj; Cordero-Mendez, Lisbeth; Dosanjh, Manjit; Eichler, Thomas; Fidarova, Elena; Gondhowiardjo, Soehartati; Gospodarowicz, Mary; Grover, Surbhi; Hande, Varsha; Harsdorf-Enderndorf, Ekaterina; Herrmann, Ken; Hofman, Michael S.; Holmberg, Ola; Jaffray, David; Knoll, Peter; Kunikowska, Jolanta; Lewis, Jason S.; Lievens, Yolande; Mikhail-Lette, Miriam; Ostwald, Dennis; Palta, Jatinder R.; Peristeris, Platon; Rosa, Arthur A.; Salem, Soha Ahmed; Dos Santos, Marcos A.; Sathekge, Mike Machaba; Shrivastava, Shyam Kishore; Titovich, Egor; Urbain, Jean-Luc; Vanderpuye, Verna; Wahl, Richard L.; Yu, Jennifer S.; Zaghloul, Mohamed Saad; Zhu, Hongcheng; Scott, Andrew M. (Elsevier, 2024-11)

  Following on from the 2015 Lancet Oncology Commission on expanding global access to radiotherapy, Radiotherapy and theranostics: a Lancet Oncology Commission was created to assess the access and availability of radiotherapy ...
• Activity quantification and dosimetry in radiopharmaceutical therapy with reference to 177Lutetium 

  Ramonaheng, Keamogetswe; Qebetu, Milani; Ndlovu, Honest; Swanepoel, Cecile; Smith, Liani; Mdanda, Sipho; Mdlophane, Amanda; Sathekge, Mike Machaba (Frontiers Media, 2024-03)

  Radiopharmaceutical therapy has been widely adopted owing primarily to the development of novel radiopharmaceuticals. To fully utilize the potential of these RPTs in the era of precision medicine, therapy must be optimized ...
• Editorial : bridging the gap to molecular imaging and theranostics 

  More, Stuart; Sathekge, Mike Machaba; Prasad, Vikas (Frontiers Media, 2024-04)

  No abstract available.
• First-in-human infection imaging with 89Zr-labelled leukocytes and comparison of scan quality with [99mTc]Tc-HMPAO-labelled leukocytes 

  Kahts, Maryke; Summers, Beverley; Ndlela, Akhona; Gutta, Aadil; Nemutaduni, Phumudzo; More, Andrew; Parsoo, Aman; Ebenhan, Thomas; Zeevaart, Jan Rijn; Aras, Omer; Sathekge, Mike Machaba (Frontiers Media, 2024-07)

  INTRODUCTION: Nuclear medicine infection imaging is routinely performed with the use of leukocytes radiolabelled with technetium-99m hexamethylpropyleneamine oxime ([99mTc]Tc-HMPAO) and single-photon emission computed ...
• Guiding principles on the education and practice of theranostics 

  Pascual, Thomas N.B.; Paez, Diana; Iagaru, Andrei; Gnanasegaran, Gopi; Lee, Sze Ting; Sathekge, Mike Machaba; Buatti, John M.; Giammarile, Francesco; Al-Ibraheem, Akram; Pardo, Manuela Arevalo; Baum, Richard P.; De Bari, Berardino; Ben-Haim, Simona; Blay, Jean-Yves; Brink, Anita; Estrada-Lobato, Enrique; Fanti, Stefano; Golubic, Anja Tea; Hatazawa, Jun; Israel, Ora; Kiess, Ana; Knoll, Peter; Louw, Lizette; Mariani, Giuliano; Mirzaei, Siroos; Orellana, Pilar; Prior, John O.; Urbain, Jean-Luc; Vichare, Shrikant; Vinjamuri, Sobhan; Virgolini, Irene; Scott, Andrew M. (Springer, 2024-07)

  PURPOSE : The recent development and approval of new diagnostic imaging and therapy approaches in the field of theranostics have revolutionised nuclear medicine practice. To ensure the provision of these new imaging and ...
• Can current preclinical strategies for radiopharmaceutical development meet the needs of targeted alpha therapy? 

  Kleynhans, Janke; Ebenhan, Thomas; Cleeren, Frederik; Sathekge, Mike Machaba (Springer, 2024-06)

  Preclinical studies are essential for effectively evaluating TAT radiopharmaceuticals. Given the current suboptimal supply chain of these radionuclides, animal studies must be refined to produce the most translatable TAT ...
• Advances in targeted alpha therapy of cancer 

  Sathekge, Mike Machaba; Morgenstern, Alfred (Springer, 2024-04)

  No abstract available.
• [18F]FDG PET and CT findings at therapy completion of pulmonary tuberculosis: comparison between HIV-positive and HIV-negative patients and impact on treatment response assessment 

  Ismaila, Aisha; Lawal, Ismaheel Opeyemi; Popoola, Gbenga O.; Mathebula, Matsontso; Moagi, Ingrid; Mokoala, Kgomotso; Honest, Ndlovu; Moeketsi, Nontando; Nchabeleng, Maphoshane; Hikuam, Chris; Hatherill, Mark; Fourie, P.B. (Petrus Bernardus); Sathekge, Mike Machaba (Springer, 2024)

  BACKGROUND : [18F]FDG-PET/CT is a sensitive non-invasive tool for assessing treatment response in patients with pulmonary tuberculosis. The data on the performance of [18F]FDG-PET/CT for response assessment among patients ...
• Recent innovations and nano-delivery of actinium-225 : a narrative review 

  Mdanda, Sipho; Ngema, Lindokuhle M.; Mdlophane, Amanda; Sathekge, Mike Machaba; Zeevaart, Jan Rijn (MDPI, 2023-06-13)

  The actinium-225 (225Ac) radioisotope exhibits highly attractive nuclear properties for application in radionuclide therapy. However, the 225Ac radionuclide presents multiple daughter nuclides in its decay chain, which ...
• Introducing HDAC-targeting radiopharmaceuticals for glioblastoma imaging and therapy 

  Everix, Liesbeth; Seane, Elsie Neo; Ebenhan, Thomas; Goethals, Ingeborg; Bolcaen, Julie (MDPI, 2023-02)

  Despite recent advances in multimodality therapy for glioblastoma (GB) incorporating surgery, radiotherapy, chemotherapy and targeted therapy, the overall prognosis remains poor. One of the interesting targets for GB ...
• PET/CT and SPECT/CT for infection in joints and bones : an overview and future directions 

  Mokoala, K.M.G. (Kgomotso); Ndlovu, Honest; Lawal, Ismaheel Opeyemi; Sathekge, Mike Machaba (Elsevier, 2024-05)

  Please read abstract in the article.
• Advances in PSMA alpha theragnostics 

  Vorster, Mariza; Sathekge, Mike Machaba (Elsevier, 2024-07)

  Alpha theranostics offer an attractive alternative form of therapy, which has best been investigated and documented with 225Ac-PSMA in patients with prostate cancer. Advantages offered by targeted alpha therapy include ...
• The SARS-COV-2 seroprevalence among oncology patients 

  Kgatle, Mankgopo; Das, Rajesh; Lawal, Ismaheel Opeyemi; Boshomane, Tebatso M.G.; Mokoala, Kgomotso M.G.; Gaspar, Cattleya; Mbokazi, Lydia; Nkambule, Nonhlanhla; Gow, Veronique; Ndlovu, Honest; Mzizi, Yonwaba; Chalwe, Joseph; Diphofa, Jeaneth; Mokobodi, Dinah; Gxekwa, Nobuhle; Zongo, Lusanda; Maphosa, Tinashe; Vorster, Mariza; Bassa, Sheynaz; Venkatesan, Amouda; Khanyile, Richard; Munga, Yunus; Ebenhan, Thomas; Zeevaart, Jan Rijn; Sathekge, Mike Machaba (MDPI, 2023-01-09)

  Patients with cancer are presumed to be vulnerable to an increased risk of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and severe clinical outcomes due to the immunocompromised state mediated ...
• Imaging PARP upregulation with [123 I]I-PARPi SPECT/CT in small cell neuroendocrine carcinoma 

  Ndlovu, Honest; Lawal, Ismaheel Opeyemi; Mokoala, Kgomotso M.G.; Disenyane, Dineo; Nkambule, Nonhlahla; Bassa, Sheynaz; Mzizi, Yonwaba; Bida, Meshack; Sathekge, Mike Machaba (Society of Nuclear Medicine and Molecular Imaging, 2024-04)

  Please read abstract in the article.
• Introducing a secondary segmentation to construct a radiomics model for pulmonary tuberculosis cavities 

  Du Plessis, Tamarisk; Ramkilawon, Gopika; Duncombe Rae, William Ian; Botha, Tanita; Martinson, Neil A.; Dixon, S.A.P.; Kyme, Andre; Sathekge, Mike Machaba (Springer, 2023-09)

  PURPOSE: Accurate segmentation (separating diseased portions of the lung from normal appearing lung) is a challenge in radiomic studies of non-neoplastic diseases, such as pulmonary tuberculosis (PTB). In this study, we ...
• Global research output of Lutetium-177 PSMA in prostate cancer : bibliometric and altmetric analyses 

  Al-Rashdan, Rakan; Al-Abdallat, Haneen; Sathekge, Mike Machaba; Mirzaei, Siroos; Shahait, Mohammed; Al-Khawaldeh, Khaled; Abdlkadir, Ahmed Saad; Lee, Szeting; Al-Ibraheem, Akram (Georg Thieme Verlag, 2024-06)

  AIM : The integration of innovative radio-pharmaceutical agents targeting prostate-specific membrane antigen (PSMA) within nuclear medicine has transformed prostate cancer detection and management. This study aims to ...
• Editorial : Impact of COVID-19 on HIV/STI screening, prevention, and treatment 

  Pyra, Maria; Mahasha, Phetole (Frontiers Media, 2023-07-17)

  No abstract available.
• Theranostics in breast cancer 

  Vorster, M.; Hadebe, B.P.; Sathekge, Mike Machaba (Frontiers Media, 2023-08-04)

  INTRODUCTION : Breast cancer is a complex disease and constitutes the leading cause of cancer in women globally. Conventional treatment modalities include surgery, chemotherapy, radiation therapy, and hormonal therapy; ...

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