The integration of digital technologies holds significant promise in enhancing accessibility to disease diagnosis and treatment at point-of-care (POC) settings. Effective implementation of such interventions necessitates ...
Kleynhans, Janke; Sathekge, Mike Machaba; Ebenhan, Thomas(Elsevier, 2023-09)
It is important to constantly monitor developments in the preclinical imaging arena of infection.
Firstly, novel radiopharmaceuticals with the correct characteristics must be identified to funnel
into the clinic. Secondly, ...
Koatale, Palesa Caroline; Welling, Mick M.; Ndlovu, Honest; Kgatle, Mankgopo; Mdanda, Sipho; Mdlophane, Amanda; Okem, Ambrose; Takyi-Williams, John; Sathekge, Mike Machaba; Ebenhan, Thomas(American Chemical Society, 2024-02)
The unique structural architecture of the peptidoglycan allows for the stratification of bacteria as either Gram-negative or Gram-positive, which makes bacterial cells distinguishable from mammalian cells. This classification ...
BACKGROUND : Ubiquicidin is a peptide fragment with selective binding to negatively charged bacterial cell membranes. Besides its earlier labelling with gamma emitting radionuclides, it has been labelled with Positron ...
OBJECTIVE : To compare cancer treatment and all-cause mortality between HIV-positive and HIV-negative cervical cancer patients in South Africa.
METHODS : We assessed cancer treatment and all-cause mortality in HIV-positive ...
Lawal, Ismaheel Opeyemi; Adediran, Omotayo Atinuke; Muzahir, Saima; Friend, Sarah; Bhave, Manali Ajay; Meisel, Jane; Torres, Mylin A.; Styblo, Toncred Marya; Graham, Cathy; Holbrook, Anna; Kalinsky, Kevin; Fielder, Bridget; Crowe, Ronald J.; Ulaner, Gary A.; Schuster, David M.(Lippincott Williams and Wilkins, 2023-01)
A 41-year-old woman with newly diagnosed invasive lobular carcinoma of the breast underwent sequential 68Ga-PSMA-11 PET/CT and 18F-fluciclovine PET/CT as part of an ongoing clinical trial (NCT04750473). 68Ga-PSMA PET/CT ...
Adediran, Omotayo A.; Lawal, Ismaheel Opeyemi; Muzahir, Saima; Bhave, Manali A.; Friend, Sarah; Fielder, Bridget; Meisel, Jane; Torres, Mylin A.; Styblo, Toncred M.; Graham, Cathy; Holbrook, Anna; Kalinsky, Kevin; Crowe, Ronald J.; Ulaner, Gary A.; Schuster, David M.(Lippincott Williams and Wilkins, 2023-04)
A 62-year-old woman with right-sided invasive lobular breast carcinoma completed external beam radiotherapy 6 weeks before undergoing a 68Ga-PSMA PET/CT and 18F-fluciclovine PET/CT scan as part of an ongoing clinical trial ...
Nuclear medicine (NM) utilizes unsealed radiation sources to diagnose and treat diseases. In the NM team, the NM physician works in collaboration with many other NM professionals who play critical roles in care delivery ...
Lawal, Ismaheel Opeyemi; Pectasides, Melina; Parihar, Ashwin Singh; Shah, Hardik U.; Halkar, Raghuveer K.; Jani, Ashesh B.; Schuster, David M.(Lippincott Williams and Wilkins, 2023-09)
68Ga–prostate-specific membrane antigen (PSMA) PET/CT is a valuable tool for staging and restaging of prostate cancer. Prostate-specific membrane antigen expression is not specific to prostate cancer, as it is expressed ...
We followed adolescents and adults living with HIV aged older than 15 years who enrolled in a South African private-sector
HIV programme to examine adherence and viral non-suppression (viral load>400 copies/mL) of ...
Ankrah, Alfred O.; Lawal, Ismaheel Opeyemi; Dierckx, Rudi A.J.O.; Sathekge, Mike Machaba; Glaudemans, Andor W.J.M.(Elsevier, 2023-01)
Over the last decades, the population at risk for invasive fungal disease (IFD) has increased because of medical therapy advances and diseases compromising patients' immune systems. The high morbidity and mortality associated ...
Prostate-specific membrane antigen (PSMA) is a transmembrane glycoprotein expressed in the majority of prostate cancer (PCa). PSMA has an enzymatic function that makes metabolic substrates such as folate available for ...
Gouws, Arno Christiaan; Kruger, Hendrik Gerhardus; Gheysens, Olivier; Zeevaart, Jan Rijn; Govender, Thavendran; Naicker, Tricia; Ebenhan, Thomas(Wiley, 2022-11)
The excellent features of non-invasive molecular imaging, its progressive technology (real-time, whole-body
imaging and quantification), and global impact by a growing infrastructure for positron emission tomography ...
Kgokolo, C.M.; Anderson, Katherine; Siwele, Shalate C.; Steel, Helen C.; Kwofie, Luyanda Laura Illicia; Sathekge, Mike Machaba; Meyer, Pieter Willem Adriaan; Rapoport, Bernardo Leon; Anderson, Ronald(Frontiers Media S.A., 2022-02-11)
Xeroderma Pigmentosum (XP), an autosomal recessive disorder characterized by ultraviolet radiation-induced abnormalities of DNA excision and repair pathways is associated with early development of cutaneous cancers. ...
INTRODUCTION : Current myocardial revascularisation guidelines recommend that patients with acute coronary syndromes be timeously revascularised. Despite these class I recommendations, immediate access to timeous ...