• Aberrant vascular anatomy associated with artifactual focal avidity in the liver on PSMA PET 

  Lawal, Ismaheel Opeyemi; Pectasides, Melina; Parihar, Ashwin Singh; Shah, Hardik U.; Halkar, Raghuveer K.; Jani, Ashesh B.; Schuster, David M. (Lippincott Williams and Wilkins, 2023-09)

  68Ga–prostate-specific membrane antigen (PSMA) PET/CT is a valuable tool for staging and restaging of prostate cancer. Prostate-specific membrane antigen expression is not specific to prostate cancer, as it is expressed ...
• Mental health, art adherence, and viral suppression among adolescents and adults living with HIV in South Africa : a cohort study 

  Haas, Andreas D.; Lienhard, Raphael; Didden, Christiane; Cornell, Morna; Folb, Naomi; Boshomane, Tebatso M.G.; Salazar‑Vizcaya, Luis; Rufeux, Yann; Nyakato, Patience; Wettstein, Anja E.; Tlali, Mpho; Davies, Mary‑Ann; Von Groote, Per; Wainberg, Milton; Egger, Matthias; Maartens, Gary; Joaska, John A. (Springer, 2023-06)

  We followed adolescents and adults living with HIV aged older than 15 years who enrolled in a South African private-sector HIV programme to examine adherence and viral non-suppression (viral load>400 copies/mL) of ...
• Imaging of invasive fungal infections- the role of PET/CT 

  Ankrah, Alfred O.; Lawal, Ismaheel Opeyemi; Dierckx, Rudi A.J.O.; Sathekge, Mike Machaba; Glaudemans, Andor W.J.M. (Elsevier, 2023-01)

  Over the last decades, the population at risk for invasive fungal disease (IFD) has increased because of medical therapy advances and diseases compromising patients' immune systems. The high morbidity and mortality associated ...
• Prognostic value of PSMA PET/CT in prostate cancer 

  Lawal, Ismaheel Opeyemi; Ndlovu, Honest; Kgatle, Mankgopo; Mokoala, K.M.G. (Kgomotso); Sathekge, Mike Machaba (Elsevier, 2023)

  Prostate-specific membrane antigen (PSMA) is a transmembrane glycoprotein expressed in the majority of prostate cancer (PCa). PSMA has an enzymatic function that makes metabolic substrates such as folate available for ...
• The clinical utility of 2-deoxy-2-[18F]fluoro-d-glucose positron emission tomography in guiding myocardial revascularisation 

  Mpanya, Dineo; Ayeni, Akinwale; More, Stuart; Hadebe, Bawinile; Sathekge, Mike Machaba; Tsabedze, Nqoba (Springer, 2022-02)

  INTRODUCTION : Current myocardial revascularisation guidelines recommend that patients with acute coronary syndromes be timeously revascularised. Despite these class I recommendations, immediate access to timeous ...
• COVID-19 Is a multi-organ aggressor : epigenetic and clinical marks 

  Kgatle, Mankgopo; Lawal, Ismaheel Opeyemi; Mashabela, Gabriel; Boshomane, Tebatso M.G.; Koatale, Palesa Caroline; Mahasha, Phetole Walter; Ndlovu, Honest; Vorster, Mariza; Rodrigues, Hosana Gomes; Zeevaart, Jan Rijn; Gordon, Siamon; Moura-Alves, Pedro; Sathekge, Mike Machaba (Frontiers Research Foundation, 2021-10-08)

  The progression of coronavirus disease 2019 (COVID-19), resulting from a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, may be influenced by both genetic and environmental factors. Several viruses ...
• Article towards facile radiolabeling and preparation of gallium-68-/bismuth-213-dota-[thi8, met(O2)11]-substance p for future clinical application : first experiences 

  Suthiram, Janine; Ebenhan, Thomas; Marjanovic-Painter, Biljana; Sathekge, Mike Machaba; Zeevaart, Jan Rijn (MDPI, 2021-08)

  Please read abstract in the article.
• Novel receptor tyrosine kinase pathway inhibitors for targeted radionuclide therapy of glioblastoma 

  Bolcaen, Julie; Nair, Shankari; Driver, Cathryn H.S.; Vandevoorde, Charlot; Boshomane, Tebatso M.G.; Ebenhan, Thomas; Vandevoorde, Charlot (MDPI, 2021-06)

  Glioblastoma (GB) remains the most fatal brain tumor characterized by a high infiltration rate and treatment resistance. Overexpression and/or mutation of receptor tyrosine kinases is common in GB, which subsequently ...
• Head-to-head intra-individual comparison of biodistribution and tumor uptake of 68Ga-FAPI and 18F-FDG PET/CT in cancer patients 

  Giesel, Frederik L.; Kratochwil, Clemens; Schlittenhardt, Joel; Dendl, Katharina; Eiber, Matthias; Staudinger, Fabian; Kessler, Lukas; Fendler, Wolfgang P.; Lindner, Thomas; Koerber, Stefan A.; Cardinale, Jens; Sennung, David; Roehrich, Manuel; Debus, Juergen; Sathekge, Mike Machaba; Haberkorn, Uwe; Calais, Jeremie; Serfling, Sebastian; Buck, Andreas L. (Springer, 2021-12)

  PURPOSE : FAPI ligands (fibroblast activation protein inhibitor), a novel class of radiotracers for PET/CT imaging, demonstrated in previous studies rapid and high tumor uptake. The purpose of this study is the head-to-head ...
• Global experience with PSMA‑based alpha therapy in prostate cancer 

  Sathekge, Mike Machaba; Bruchertseifer, Frank; Vorster, Mariza; Morgenstern, Alfred; Lawal, Ismaheel Opeyemi (Springer, 2021-12)

  PURPOSE : This review discusses the current state of prostate-specific membrane antigen (PSMA)-based alpha therapy of metastatic castration-resistant prostate cancer (mCRPC). With this in-depth discussion on the growing ...
• 68Ga-FAPI-PET/CT in patients with various gynecological malignancies 

  Dendl, Katharina; Koerber, Stefan A.; Finck, Rebecca; Mokoala, K.M.G. (Kgomotso); Staudinger, Fabian; Schillings, Lisa; Heger, Ulrike; Rohrich, Manuel; Kratochwil, Clemens; Sathekge, Mike Machaba; Jager, Dirk; Debus, Jurgen; Haberkorn, Uwe; Giesel, Frederik L. (Springer, 2021-11)

  PURPOSE : 68Ga-FAPI (fibroblast activation protein inhibitor) is a novel and highly promising radiotracer for PET/CT imaging. The aim of this retrospective analysis is to explore the potential of FAPI-PET/CT in gynecological ...
• The added value of [F-18]FDG PET/CT in the management of invasive fungal infections 

  Ankrah, Alfred O.; Creemers-Schild, Dina; De Keizer, Bart; Klein, Hans C.; Dierckx, Rudi A.J.O.; Kwee, Thomas C.; Span, Lambert F.R.; De Jong, Pim A.; Sathekge, Mike Machaba; Glaudemans, Andor W.J.M. (MDPI, 2021-01-17)

  Anatomy-based imaging methods are the usual imaging methods used in assessing invasive fungal infections (IFIs). [18F]FDG PET/CT has also been used in the evaluation of IFIs. We assessed the added value of [18F]FDG PET/CT ...
• Radionuclide imaging of invasive fungal disease in immunocompromised hosts 

  Lawal, Ismaheel Opeyemi; Mokoala, K.M.G. (Kgomotso); Kgatle, Mankgopo; Dierckx, Rudi A.J.O.; Glaudemans, Andor W.J.M.; Sathekge, Mike Machaba; Ankrah, Alfred O. (MDPI, 2021-11-06)

  Invasive fungal disease (IFD) leads to increased mortality, morbidity, and costs of treatment in patients with immunosuppressive conditions. The definitive diagnosis of IFD relies on the isolation of the causative fungal ...
• The outcome and safety of re-challenge Lutetium-177 PSMA (177Lu-PSMA) therapy with Low-Dose Docetaxel as a Radiosensitizer—a promising combination in metastatic castrate-resistant prostate cancer (mCRPC) : a case report 

  Maharaj, Masha; Heslop, Lucille; Govender, Trisha; Korowlay, Nisaar; Singh, Aviral; Choudhary, Partha; Sathekge, Mike Machaba (Springer, 2021-06)

  Please read abstract in the article.
• PSMA theranostics : science and practice 

  Mokoala, K.M.G. (Kgomotso); Lawal, Ismaheel Opeyemi; Lengana, Thabo; Kgatle, Mankgopo; Giesel, Frederik L.; Vorster, Mariza; Sathekge, Mike Machaba (MDPI, 2021-08-02)

  Prostate cancer (PCa) causes significant morbidity and mortality in men globally. While localized PCa may be managed with curative intent by surgery and/or radiation therapy, the management of advanced hormone resistant ...
• Preclinical assessment addressing intravenous administration of a [68Ga]Ga-PSMA-617 microemulsion : acute in vivo toxicity, tolerability, PET imaging, and biodistribution 

  Mandiwana, Vusani; Kalombo, Lonji; Hayeshi, Rose; Zeevaart, Jan Rijn; Ebenhan, Thomas (MDPI Publishing, 2021-04-30)

  It has been herein presented that a microemulsion, known to be an effective and safe drug delivery system following intravenous administration, can be loaded with traces of [68Ga]Ga-PSMA- 617 without losing its properties ...
• Diagnostic value of sentinel lymph node scintigraphy and 2‐[18F]‐fluoro‐2‐deoxy‐D‐glucose positron emission tomography/computed tomography in the detection of metastatic lymph nodes in patients with early‐stage cervical cancer 

  Reyneke, Florette; Snyman, Leon Cornelius; Lawal, Ismaheel Opeyemi; Lengana, Thabo (Medknow Publications, 2020-07)

  Cervical cancer is staged clinically using the International Federation of Gynaecology and Obstetrics staging system. Although lymph node status does not form part of the staging, it has important prognostic and potential ...
• Microwave-assisted synthesis of meso-carboxyalkyl-BODIPYs and an application to fluorescence imaging 

  Mhlongo, Neliswa Z.; Ebenhan, Thomas; Driver, Cathryn H.S.; Maguire, Glenn E.M.; Kruger, Hendrick G.; Govender, Thavendran; Naicker, Tricia (Royal Society of Chemistry, 2020-10)

  Please read abstract in the article.
• Target heterogeneity in oncology : the best predictor for differential response to radioligand therapy in neuroendocrine tumors and prostate cancer 

  Puranik, Ameya D.; Dromain, Clarisse; Fleshner, Neil; Sathekge, Mike Machaba; Pavel, Marianne; Eberhardt, Nina; Zengerling, Friedemann; Marienfeld, Ralf; Grunert, Michael; Prasad, Vikas (MDPI, 2021)

  Tumor or target heterogeneity (TH) implies presence of variable cellular populations having different genomic characteristics within the same tumor, or in different tumor sites of the same patient. The challenge is to ...
• FDG PET/CT for evaluating systemic arterial inflammation induced by anthracycline-based chemotherapy of Hodgkin lymphoma : a retrospective cohort study 

  Lawal, Ismaheel Opeyemi; Orunmuyi, Akintunde T.; Popoola, Gbenga O.; Lengana, Thabo; Mokoala, K.M.G. (Kgomotso); Ankrah, Alfred O.; Sathekge, Mike Machaba (Lippincott, Williams and Wilkins:, 2020-11)

  To evaluate arterial fluorodeoxyglucose (FDG) uptake as a marker of arterial inflammation in multiple vascular beds in patients treated with anthracycline-based chemotherapy for Hodgkin lymphoma (HL). We used maximum ...

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