Wolmarans, Elize; Boy, S.C. (Sonja); Nel, Sulette; Mercier, Anne Elisabeth; Pepper, Michael Sean(Springer, 2017-11)
The recurrence and/or lack of response of certain tumors to radio- and chemotherapy has been attributed to a small subpopulation of cells termed cancer stem cells (CSCs). CSCs have been identified in many tumors (including ...
Grobbelaar, Simone; Mercier, Anne Elisabeth; Van den Bout, Iman; Durandt, Chrisna; Pepper, Michael Sean(Wiley, 2024-01)
The generation of tissue from stem cells is an alluring concept as it holds a number of potential applications in clinical therapeutics and regenerative medicine. Mesenchymal stromal/stem cells (MSCs) can be isolated from ...
Helena, Jolene Michelle; Joubert, Anna Margaretha; Grobbelaar, Simone; Nolte, Elsie Magdalena; Nel, Marcel; Pepper, Michael Sean; Coetzee, Magdalena; Mercier, Anne Elisabeth(MDPI Publishing, 2018-04-11)
Deoxyribonucleic acid (DNA) is the self-replicating hereditary material that provides a
blueprint which, in collaboration with environmental influences, produces a structural and functional
phenotype. As DNA coordinates ...
Grobbelaar, Simone; Mercier, Anne Elisabeth; Verburgh, Estelle; Brittain, David; Pepper, Michael Sean(Health and Medical Publishing Group, 2019-08)
The growing need for haematopoietic stem cell transplantation (HSCT) is reflected in the increasing number of transplants performed
globally each year. HSCT provides life-changing and potentially curative therapy for a ...
