Browsing Research Articles (Immunology) by Title

Browsing Research Articles (Immunology) by Title

Sort by: Order: Results:

  • Spatial analyses of immune cell infiltration in cancer : current methods and future directions. A report of the International Immuno-Oncology Biomarker Working Group on Breast Cancer 
    Page, David B.; Broeckx, Glenn; Jahangir, Chowdhury Arif; Verbandt, Sara; Gupta, Rajarsi R.; Thagaard, Jeppe; Khiroya, Reena; Kos, Zuzana; Abduljabbar, Khalid; Acosta Haab, Gabriela; Acs, Balazs; Almeida, Jonas S.; Alvarado-Cabrero, Isabel; Azmoudeh-Ardalan, Farid; Badve, Sunil; Baharun, Nurkhairul Bariyah; Bellolio, Enrique R.; Bheemaraju, Vydehi; Blenman, Kim R.M.; Botinelly Mendonca Fujimoto, Luciana; Burgues, Octavio; Cheang, Maggie Chon U.; Ciompi, Francesco; Cooper, Lee A.D.; Coosemans, An; Corredor, German; Dantas Portela, Flavio Luis; Deman, Frederik; Demaria, Sandra; Dudgeon, Sarah N.; Elghazawy, Mahmoud; Ely, Scott; Fernandez-Martin, Claudio; Fineberg, Susan; Fox, Stephen B.; Gallagher, William M.; Giltnane, Jennifer M.; Gnjatic, Sacha; Gonzalez-Ericsson, Paula I.; Grigoriadis, Anita; Halama, Niels; Hanna, Matthew G.; Harbhajanka, Aparna; Hardas, Alexandros; Hart, Steven N.; Hartman, Johan; Hewitt, Stephen; Hida, Akira I.; Horlings, Hugo M.; Husain, Zaheed; Hytopoulos, Evangelos; Irshad, Sheeba; Janssen, Emiel A.M.; Kahila, Mohamed; Kataoka, Tatsuki R.; Kawaguchi, Kosuke; Kharidehal, Durga; Khramtsov, Andrey I.; Kiraz, Umay; Kirtani, Pawan; Kodach, Liudmila L.; Korski, Konstanty; Kovacs, Aniko; Laenkholm, Anne-Vibeke; Lang-Schwarz, Corinna; Larsimont, Denis; Lennerz, Jochen K.; Lerousseau, Marvin; Li, Xiaoxian; Ly, Amy; Madabhushi, Anant; Maley, Sai K.; Manur Narasimhamurthy, Vidya; Marks, Douglas K.; McDonald, Elizabeth S.; Mehrotra, Ravi; Michiels, Stefan; Minhas, Fayyaz ul Amir Afsar; Mittal, Shachi; Moore, David A.; Mushtaq, Shamim; Nighat, Hussain; Papathomas, Thomas; Penault-Llorca, Frederique; Perera, Rashindrie D.; Pinard, Christopher J.; Pinto-Cardenas, Juan Carlos; Pruneri, Giancarlo; Pusztai, Lajos; Rahman, Arman; Rajpoot, Nasir Mahmood; Rapoport, Bernardo Leon; Rau, Tilman T.; Reis-Filho, Jorge S.; Ribeiro, Joana M.; Rimm, David; Salomon, Anne-Vincent; Salto-Tellez, Manuel; Saltz, Joel; Sayed, Shahin; Siziopikou, Kalliopi P.; Sotiriou, Christos; Stenzinger, Albrecht; Sughayer, Maher A.; Sur, Daniel; Symmans, Fraser; Tanaka, Sunao; Taxter, Timothy; Tejpar, Sabine; Teuwen, Jonas; Thompson, E. Aubrey; Tramm, Trine; Tran, William T.; Van Der Laak, Jeroen; Van Diest, Paul J.; Verghese, Gregory E.; Viale, Giuseppe; Vieth, Michael; Wahab, Noorul; Walter, Thomas; Waumans, Yannick; Wen, Hannah Y.; Yang, Wentao; Yuan, Yinyin; Adams, Sylvia; Bartlett, John Mark Seaverns; Loibl, Sibylle; Denkert, Carsten; Savas, Peter; Loi, Sherene; Salgado, Roberto; Specht Stovgaard, Elisabeth; Akturk, Guray; Bouchmaa, Najat (Wiley, 2023-08)
    Modern histologic imaging platforms coupled with machine learning methods have provided new opportunities to map the spatial distribution of immune cells in the tumor microenvironment. However, there exists no standardized ...
  • Special edition of the SAMJ devoted to cell and gene therapy 
    Pepper, Michael Sean (Health and Medical Publishing Group, 2019-08)
    BACKGROUND: In South Africa (SA), the largest category of perinatal deaths is unexplained stillbirths. Two-thirds of these occur in the antenatal period and most fetuses are macerated, but at antenatal clinics the mothers ...
  • Spectrum of MYO7A mutations in an indigenous South African population further elucidates the nonsyndromic autosomal recessive phenotype of DFNB2 to include both homozygous and compound heterozygous mutations 
    Kabahuma, Rosemary Ida; Schubert, Wolf-Dieter; Labuschagne, Christiaan; Yan, Denise; Blanton, Susan Halloran; Pepper, Michael Sean; Liu, Xue Zhong (MDPI, 2021-02-15)
    MYO7A gene encodes unconventional myosin VIIA, which, when mutated, causes a phenotypic spectrum ranging from recessive hearing loss DFNB2 to deaf-blindness, Usher Type 1B (USH1B). MYO7A mutations are reported in nine DFNB2 ...
  • Sperm macrocephaly syndrome in the ostrich Struthio camelus : morphological characteristics and implications for motility 
    Du Plessis, Lizette; Bonato, M.; Durandt, Chrisna; Cloete, S.W.P.; Soley, John Thomson (CSIRO Publishing, 2019)
    Sperm macrocephaly syndrome (SMS) is characterised by a high percentage of spermatozoa with enlarged heads and multiple tails, and is related to infertility. Although this multiple sperm defect has been described in other ...
  • A standardized framework for accurate, high-throughput genotyping of recombinant and non-recombinant viral sequences 
    Alcantara, Luiz Carlos Junior; Cassol, Sharon; Libin, Pieter; Deforche, Koen; Pybus, Oliver G.; Van Ranst, Marc; Galvao-Castro, Bernardo; Vandamme, Anne-Mieke; De Oliveira, Tulio (Oxford University Press, 2009-07)
    Human immunodeficiency virus type-1 (HIV-1), hepatitis B and C and other rapidly evolving viruses are characterized by extremely high levels of genetic diversity. To facilitate diagnosis and the development of prevention ...
  • The stem cell regulatory environment in South Africa - cause for concern 
    Pepper, Michael Sean (Health and Medical Publishing Group, 2009-07)
    Every innovation in medicine is met with a mixture of excitement, expectation and a certain degree of apprehension. Nowhere is this more apparent than in the field of cellbased therapy, i.e. the application of cells to ...
  • Stem cell research engenders interdisciplinary collaboration in science, ethics and religion 
    Meissner-Roloff, Madelein; Pepper, Michael Sean (Academy of Science of South Africa, 2012-05)
    No abstract available.
  • Stem cell therapy for neurological disorders 
    Alessandrini, M.; Preynat-Seauve, O.; De Bruin, K.; Pepper, Michael Sean (Health and Medical Publishing Group, 2019-08)
    Neurological disease encompasses a diverse group of disorders of the central and peripheral nervous systems, which collectively are the leading cause of disease burden globally. The scope of treatment options for neurological ...
  • Stem cell tourism and spinal cord injury in South Africa 
    Skeen, M.; Eksteen, Carina A.; Pepper, Michael Sean (Health and Medical Publishing Group, 2019-08)
    Imagine a world in which disease management is highly personalised. Drug treatments would be specific to the individual concerned, taking into account genetic background and environmental factors. Therapies would be ...
  • Stem cell tourism in South Africa : a legal update 
    Nothling-Slabbert, Melodie; Pepper, Michael Sean; Mahomed, S. (Health and Medical Publishing Group, 2015-08)
    The past few years have seen a sharp rise in the propagation of unproven stem cell ‘treatments’, also known as ‘stem cell tourism’. Patients suffering from a variety of diseases unresponsive to conventional medical therapy ...
  • Step-by-step assembly and testing of a low-cost bioprinting solution for research and educational purposes 
    Honiball, John Robert; Pepper, Michael Sean; Prinsloo, Earl (Elsevier, 2021)
    Bioprinting is a rapidly expanding technology with the ability to fabricate in vitro three-dimensional (3D) tissues in a layer-by-layer manner to ultimately produce a living tissue which physiologically resembles native ...
  • Study on causes of fever in primary healthcare center uncovers pathogens of public health concern in Madagascar 
    Guillebaud, Julia; Bernardson, Barivola; Randriambolamanantsoa, Tsiry Hasina; Randrianasolo, Laurence; Randriamampionona, Jane Lea; Marino, Cesare Augusto; Rasolofo, Voahangy; Randrianarivelojosia, Milijaona; Vigan-Womas, Ines; Stivaktas, Voul; Venter, Marietjie; Piola, Patrice; Heraud, Jean-Michel (Public Library of Science, 2018-07-16)
    BACKGROUND : The increasing use of malaria diagnostic tests reveals a growing proportion of patients with fever but no malaria. Clinicians and health care workers in low-income countries have few tests to diagnose ...
  • Supportive care in patients with cancer during the COVID-19 pandemic 
    Aapro, Matti; Lyman, G.H.; Bokemeyer, C.; Rapoport, Bernardo Leon; Mathieson, N.; Koptelova, N.; Cornes, P.; Anderson, Ronald; Gascon, P.; Kuderer, N.M. (Elsevier, 2021)
    Cancer care has been profoundly impacted by the global pandemic of severe acute respiratory syndrome coronavirus 2 disease (coronavirus disease 2019, COVID-19), resulting in unprecedented challenges. Supportive care is an ...
  • Sustaining essential healthcare in Africa during the COVID-19 pandemic 
    Ongole, J.J.; Rossouw, Theresa M.; Fourie, P.B. (Petrus Bernardus); Stoltz, Anton Carel; Hugo, Johannes F.M.; Marcus, Tessa S. (International Union Against Tuberculosis and Lung Disease, 2020-06)
    No abstract available.
  • Synergies, tensions and challenges in HIV prevention, treatment and cure research : exploratory conversations with HIV experts in South Africa 
    Moodley, Keynthri; Rossouw, Theresa M.; Staunton, Ciara; Colvin, Christopher J. (BioMed Central, 2016-04-30)
    BACKGROUND : The ethical concerns associated with HIV prevention and treatment research have been widely explored in South Africa over the past 3 decades. However, HIV cure research is relatively new to the region ...
  • Systemic immune activation profiles of HIV-1 subtype C-infected children and their mothers 
    Makhubele, Tinyiko G.; Steel, Helen C.; Anderson, Ronald; Van Dyk, Gisela; Theron, Annette J.; Rossouw, Theresa M. (Hindawi Publishing, 2016)
    Little is known about immune activation profiles of children infected with HIV-1 subtype C. The current study compared levels of selected circulating biomarkers of immune activation in HIV-1 subtype C-infected untreated ...
  • Systemic immune dysregulation in early breast cancer is associated with decreased plasma levels of both soluble co-inhibitory and co-stimulatory immune checkpoint molecules 
    Rapoport, Bernardo Leon; Steel, Helen C.; Hlatshwayo, Nomsa; Theron, Annette J.; Meyer, Pieter Willem Adriaan; Nayler, Simon; Benn, Carol-Ann; Smit, Teresa; Kwofie, Luyanda Laura Illicia; Heyman, Liezl; Anderson, Ronald (Fronties Media SA, 2022-05-23)
    Breast cancer cells exploit the up-regulation or down-regulation of immune checkpoint proteins to evade anti-tumor immune responses. To explore the possible involvement of this mechanism in promoting systemic immunosuppression, ...
  • Systemic levels of the soluble co-inhibitory immune checkpoints, CTLA-4, LAG-3, PD-1/PD-L1 and TIM-3 are markedly increased in basal cell carcinoma 
    Malinga, Nonkululeko Z.; Siwele, Shalate C.; Steel, Helen C.; Kwofie, Luyanda Laura Illicia; Meyer, Pieter Willem Adriaan; Smit, Teresa; Anderson, Ronald; Rapoport, Bernardo Leon; Kgokolo, C.M. (Elsevier, 2022-05)
    Although co-inhibitory immune checkpoint proteins are primarily involved in promoting cell-cell interactions that suppress adaptive immunity, especially tumor immunity, the soluble cell-free variants of these molecules ...
  • T cell responses to SARS-CoV-2 spike cross-recognize Omicron 
    Keeton, Roanne; Tincho, Marius B.; Ngomti, Amkele; Baguma, Richard; Benede, Ntombi; Suzuki, Akiko; Khan, Khadija; Cele, Sandile; Bernstein, Mallory; Karim, Farina; Madzorera, Sharon V.; Moyo-Gwete, Thandeka; Mennen, Mathilda; Skelem, Sango; Adriaanse, Marguerite; Mutithu, Daniel; Aremu, Olukayode; Stek, Cari; Du Bruyn, Elsa; Van der Mescht, Mieke Adri; De Beer, Zelda; De Villiers, Talita R.; Bodenstein, Annie; Van den Berg, Gretha; Mendes, Adriano; Strydom, Amy; Venter, Marietjie; Giandhari, Jennifer; Naidoo, Yeshnee; Pillay, Sureshnee; Tegally, Houriiyah; Grifoni, Alba; Weiskopf, Daniela; Sette, Alessandro; Wilkinson, Robert J.; De Oliveira, Tulio; Bekker, Linda‑Gail; Gray, Glenda; Ueckermann, Veronica; Rossouw, Theresa; Boswell, M.T.; Bhiman, Jinal N.; Moore, Penny L.; Sigal, Alex; Ntusi, Ntobeko A.B.; Burgers, Wendy A.; Riou, Catherine (Nature Research, 2022-03-17)
    The SARS-CoV-2 Omicron variant (B.1.1.529) has multiple spike protein mutations1,2 that contribute to viral escape from antibody neutralization3–6 and reduce vaccine protection from infection7,8. The extent to which other ...
  • Tachykinin receptor-selectivity of the potential glioblastoma-targeted therapy, DOTA-[Thi8,Met(O2)11]-substance P 
    Suthiram, Janine; Pieters, Ane; Moosa, Zulfiah Mohamed; Zeevaart, Jan Rijn; Sathekge, Mike Machaba; Ebenhan, Thomas; Anderson, Ross Calley; Newton, Claire L. (MDPI, 2023-01)
    Please read abstract in article.