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Browsing Immunology by Author "Anderson, Ronald"
Now showing items 1-20 of 123
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Van der Mescht, Mieke Adri; De Beer, Zelda; Steel, Helen C.; Anderson, Ronald; Masenge, Andries; Moore, Penny L.; Bastard, Paul; Casanova, Jean-Laurent; Abdullah, Fareed; Ueckermann, Veronica; Rossouw, Theresa M. (Elsevier, 2024-09)The African continent reported the least number of COVID-19 cases and deaths of all the continents, although the exact reasons for this are still unclear. In addition, little is known about the immunological profiles ...
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Opolot, J.O.; Theron, Annette J.; Anderson, Ronald; Feldman, Charles (Springer, 2015-02)INTRODUCTION : Despite the high burden of disease, there have been surprisingly few studies of the acute phase and plasma catecholamine/cortisol stress hormone responses in patients with active pulmonary tuberculosis. ...
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Anderson, Ronald; Theron, Annette J.; Steel, Helen C.; Nel, Jan Gert; Tintinger, Gregory Ronald (MDPI Publishing, 2020-12)This study probed the di erential utilization of P2Y1 and P2Y12 receptors in mobilizing CD62P (P-selectin) from intracellular granules following activation of human platelets with adenosine 50-diphosphate (ADP, 100 mol L1) ...
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Feldman, Charles; Anderson, Ronald (Thieme Publishing, 2012-06)Community-acquired pneumonia remains an important cause of disease and death both in the developed and the developing worlds and therefore continues to have major medical impact. The mortality remains high despite the ...
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Mashele, Sizeka Aubrey; Steel, Helen C.; Matjokotja, Maborwa T.; Rasehlo, S.S.M. (Sipho); Anderson, Ronald; Cholo, Moloko C. (Elsevier, 2022-06)OBJECTIVES : The chemotherapeutic regimens of patients with drug-susceptible (DS)- tuberculosis (TB) comprise four primary anti-TB drugs: rifampicin (RMP), isoniazid (INH), ethambutol (EMB) and pyrazinamide (PZA), administered ...
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Adebayo, Salmon A.; Shai, Leshweni Jeremia; Cholo, Moloko C.; Anderson, Ronald; Du Toit, D. (Water Research Commission, 2014-04)Notwithstanding direct detection of microbial/viral pathogens or their associated toxins, the quality of drinking water may also be evaluated according to its pro-inflammatory potential. In this latter setting, contamination ...
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Feldman, Charles; Anderson, Ronald (Adis, 2011-01)Streptococcus pneumoniae is the major bacterial cause of pneumonia, meningitis and otitis media and continues to be associated with significant morbidity and mortality in individuals both in the developed and developing ...
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Feldman, Charles; Anderson, Ronald (Thieme Publishing, 2016-04)Opportunistic bacterial and fungal infections of the lower respiratory tract, most commonly those caused by Streptococcus pneumoniae (the pneumococcus), Mycobacterium tuberculosis, and Pneumocystis jirovecii, remain the ...
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Anderson, Ronald; Theron, Annette J.; Steel, Helen C.; Durandt, Chrisna; Tintinger, Gregory Ronald; Feldman, Charles (Hindawi Publishing Corporation, 2014-03)The clinical relevance of the anti-inflammatory properties of beta-2 agonists remains contentious possibly due to differences in their molecular structures and agonist activities. The current study has compared the effects ...
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Cockeran, Riana; Dix-Peek, Therese; Dickens, Caroline; Steel, Helen C.; Anderson, Ronald; Feldman, Charles (Elsevier, 2020-02)OBJECTIVES : Exposure to cigarette smoke impacts on the virulence of Streptococcus pneumoniae (pneumococcus) by mechanisms including induction of biofilm formation. Most studies, however, have focused on individual strains ...
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Feldman, Charles; Anderson, Ronald (South African Thoracic Society, 2020)COVID-19 pneumonia, much like that of bacterial and viral community-acquired pneumonia before it, is accompanied by a high rate of cardio- and cerebrovascular events that are associated with an increased risk of complications ...
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Blidner, Ada Gabriela; Choi, Jennifer; Cooksley, Tim; Dougan, Michael; Glezerman, Ilya; Ginex, Pamela; Girotra, Monica; Gupta, Dipti; Johnson, Douglas; Shannon, Vickie R.; Suarez-Almazor, Maria; Rapoport, Bernardo Leon; Anderson, Ronald (Springer, 2020-12)Despite the success and ongoing promise of monoclonal antibody–targeted immune checkpoint inhibitor immunotherapy of advanced malignancies, in particular, antibodies directed against CTLA-4 and PD-1/PD-L1, the development ...
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Cardiac troponin T as a predictor of short- and long-term mortality in community-acquired pneumonia Feldman, Charles; Anderson, Ronald (Wiley, 2017-07)The association between severe community-acquired pneumonia (CAP) and a significantly heightened risk for development of an acute cardiovascular event (ACE), most commonly acute myocardial infarction, new-onset arrhythmia ...
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Cockeran, Riana; Steel, Helen C.; Theron, Annette J.; Mitchell, Timothy J.; Feldman, Charles; Anderson, Ronald (Elsevier, 2011-11)The pneumolysin toxoid, Δ6 PLY, is a prototype pneumococcal protein vaccine candidate. However, its potentially detrimental residual pro-inflammatory interactions with human neutrophils are unknown. In the current study ...
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Cigarette smoke condensate attenuates phorbol ester-mediated neutrophil extracellular trap formation Bokaba, Refilwe Philadelphia; Anderson, Ronald; Theron, Annette J.; Tintinger, Gregory Ronald (Makerere University Medical School, 2017-09)BACKGROUND : Neutrophil extracellular traps (NETs) constitute a network of chromatin fibres containing histone and antimicrobial peptides that are released by activated neutrophils. NETs protect the host against infection ...
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Matapa, Kgashane Given; Dix-Peek, Therese; Cockeran, Riana; Anderson, Ronald; Steel, Helen C.; Feldman, Charles (European Publishing, 2019-11)INTRODUCTION : Cigarette smoking is a well-recognized risk factor for development of severe, invasive pneumococcal disease. However, little is known about the direct effects of exposure to cigarette smoke on the virulence ...
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Malherbe, Glen Pierre; Steel, Helen C.; Cassol, Sharon; De Oliveira, Tulio; Seebregts, Christopher J.; Anderson, Ronald; Cassol, Edana; Rossouw, Theresa M. (Hindawi Publishing Corporation, 2014-04-06)Please read abstract in article.
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Meyer, Pieter Willem Adriaan; Hodkinson, Bridget; Ally, Mahmood Moosa Tar Mahomed; Musenge, Eustasius; Wadee, Ahmed A.; Fickl, Heidi; Tikly, Mohammed; Anderson, Ronald (Hindawi Publishing Corporation, 2010)Our objective was to analyse the relationship between circulating cytokines, autoantibodies, acute phase reactants, and disease activity in DMARDs-na¨ıve rheumatoid arthritis (RA) patients (n = 140). All cytokines were ...
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Anderson, Ronald; Steel, Helen C.; Cockeran, Riana; Smith, Anthony Marius; Von Gottberg, Anne; De Gouveia, L.; Brink, Andries J.; Klugman, Keith P.; Mitchell, Timothy J.; Feldman, Charles (Oxford University Press, 2007-02)Please refer to abstract in article
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Cholo, Moloko C.; Steel, Helen C.; Fourie, P.B. (Petrus Bernardus); Germishuizen, Willem Andreas; Anderson, Ronald (Oxford University Press, 2012-02)Clofazimine, a lipophilic riminophenazine antibiotic, possesses both antimycobacterial and anti-inflammatory activities. However, its efficacy has been demonstrated only in the treatment of leprosy, not in human tuberculosis, ...
Now showing items 1-20 of 123