- UPSpace Home
- →
- Health Sciences
- →
- Medical Microbiology
- →
- Research Articles (Medical Microbiology)
- →
- Browsing Research Articles (Medical Microbiology) by UP Author
JavaScript is disabled for your browser. Some features of this site may not work without it.
Browsing Research Articles (Medical Microbiology) by UP Author "Ismail, Nazir Ahmed"
Now showing items 21-40 of 60
-
Omar, Shaheed Vally; Peters, Remco P.H.; Ismail, Nazir Ahmed; Jonkman, Kelly; Dreyer, Andries W.; Said, Halima M.; Gwalab, Thabisile; Ismail, Nabila; Fourie, P.B. (Petrus Bernardus) (Wiley, 2016-06)Molecular tests are revolutionizing diagnosis of tuberculosis (TB). Disease burden is concentrated in resource-poor countries with inadequate infrastructure and capacity resulting in delays for specimens to reach the ...
-
Ferrian, Selena; Ross, Melinda; Conradie, Francesca; Omar, Shaheed Vally; Ismail, Nazir Ahmed; Little, Francesca; Kaplan, Gilla; allows, Dorothy F; Gray, Clive M. (Frontiers Media, 2018-10-25)Identifying a blood circulating cellular biomarker that can be used to assess severity of disease and predict the time to culture conversion (TCC) in patients with multidrug resistant tuberculosis (MDR-TB) would facilitate ...
-
Zignol, Matteo; Cabibbe, Andrea Maurizio; Dean, Anna S.; Glaziou, Philippe; Alikhanova, Natavan; Ama, Cecilia; Andres, Sonke; Barbova, Anna; Borbe-Reyes, Angeli; Chin, Daniel P.; Cirillo, Daniela Maria; Colvin, Charlotte; Dadu, Andrei; Dreyer, Andries; Driesen, Michele; Gilpin, Christopher; Hasan, Rumina; Hasan, Zahra; Hoffner, Sven; Hussain, Alamdar; Ismail, Nazir Ahmed; Kamal, S.M. Mostofa; Khanzada, Faisal Masood; Kimerling, Michael; Kohl, Thomas Andreas; Mansjo, Mikael; Miotto, Paolo; Mukadi, Ya Diul; Mvusi, Lindiwe; Niemann, Stefan; Omar, Shaheed Vally; Rigouts, Leen; Schito, Marco; Sela, Ivita; Seyfaddinova, Mehriban; Skenders, Girts; Skrahina, Alena; Tahseen, Sabira; Wells, William A.; Zhurilo, Alexander; Weyer, Karin; Floyd, Katherine; Raviglione, Mario C. (Elsevier, 2018-06)BACKGROUND : In many countries, regular monitoring of the emergence of resistance to anti-tuberculosis drugs is hampered by the limitations of phenotypic testing for drug susceptibility. We therefore evaluated the use ...
-
Georghiou, Sophia B.; Schumacher, Samuel G.; Rodwell, Timothy C.; Colman, Rebecca E.; Miotto, Paolo; Gilpin, Christopher; Ismail, Nazir Ahmed; Rodrigues, Camilla; Warren, Rob; Weyer, Karin; Zignol, Matteo; Arafah, Sonia; Cirillo, Daniela Maria; Denkinger, Claudia M. (Oxford University Press, 2019-10)The development and implementation of rapid molecular diagnostics for tuberculosis (TB) drug-susceptibility testing is critical to inform treatment of patients and to prevent the emergence and spread of resistance. Optimal ...
-
Ndjeka, Norbert; Schnippel, Kathryn; Master, Iqbal; Meintjes, Graeme; Maartens, Gary; Romero, Rodolfo; Padanilam, Xavier; Enwerem, Martin; Chotoo, Sunitha; Singh, Nalini; Hughes, Jennifer; Variava, Ebrahim; Ferreira, Hannetjie; Te Riele, Julian; Ismail, Nazir Ahmed; Mohr, Erika; Bantubani, Nonkqubela; Conradie, Francesca (European Respiratory Society, 2018-12)South African patients with rifampicin-resistant tuberculosis (TB) and resistance to fluoroquinolones and/or injectable drugs (extensively drug-resistant (XDR) and preXDR-TB) were granted access to bedaquiline through a ...
-
Habte, T.M.; Dube, S.; Ismail, Nazir Ahmed; Hoosen, Anwar Ahmed (Health and Medical Publishing Group, 2009-08)AIM: To investigate the profile of common uropathogens isolated from urine specimens submitted to the diagnostic microbiology laboratory at a tertiary teaching hospital and assess their antimicrobial susceptibility patterns ...
-
Earle, Sarah G.; Wu, Chieh-Hsi; Charlesworth, Jane; Stoesser, Nicole; Gordon, N. Claire; Walker, Timothy M.; Spencer, Chris C.A.; Iqbal, Zamin; Clifton, David A.; Hopkins, Katie L.; Woodford, Neil; Smith, E. Grace; Ismail, Nazir Ahmed; Llewelyn, Martin J.; Peto, Tim E.; Crook, Derrick W.; McVean, Gil; Walker, A. Sarah; Wilson, Daniel J. (Springer Nature, 2016-04-04)Bacteria pose unique challenges for genome-wide association studies because of strong structuring into distinct strains and substantial linkage disequilibrium across the genome1,2. Although methods developed for human ...
-
Ismail, Nazir Ahmed; Omar, Shaheed Vally; Ismail, Nabila; Peters, Remco P.H. (Elsevier, 2018-10)Bedaquiline, clofazimine and linezolid are pertinent drugs for drug-resistant tuberculosis. Drug-resistant mutants provide insight into important resistance acquisition mechanisms. Methods for in vitro Mycobacterium ...
-
Ismail, Nabila; Ismail, Nazir Ahmed; Omar, Shaheed Vally; Peters, Remco P.H. (American Society for Microbiology, 2019-08)Bedaquiline resistance within Mycobacterium tuberculosis may arise through efflux-based (rv0678) or target-based (atpE) pathway mutations. M. tuberculosis mutant populations from each of five sequential steps in a passaging ...
-
Lim, Jennifer R.; Gandhi, Neel R.; Mthiyane, Thuli; Mlisana, Koleka; Moodley, Julie; Jaglal, Prenika; Ramdin, Neeshan; Brust, James C.M.; Ismail, Nazir Ahmed; Rustomjee, Roxana; Shah, N. Sarita (Public Library of Science, 2015-07-06)South Africa is experiencing a widespread drug-resistant tuberculosis epidemic, although data are limited regarding the current situation. This study finds that the extensively drugresistant tuberculosis (XDR-TB) incidence ...
-
Mwansa‑Kambafwile, Judith R.M.; Chasela, Charles; Ismail, Nazir Ahmed; Menezes, Colin (BioMed Central, 2019-11-08)INTRODUCTION : Tuberculosis (TB) is a problem in South Africa. Initial loss to follow up (LTFU) among TB patients is high varying between 14.9 and 18%. Some of the reasons for this are: lack of proper communication between ...
-
Omar, Shaheed Vally; Peters, Remco P.H.; Ismail, Nazir Ahmed; Dreyer, Andries W.; Said, Mohamed; Gwala, Thabisile; Ismail, Nabila; Fourie, P.B. (Petrus Bernardus) (Elsevier, 2015-10)BACKGROUND : Modern molecular-based approaches for the detection of Mycobacterium tuberculosis in sputum samples promise quicker and more accurate detection of cases. However, processing sputum samples at central diagnostic ...
-
Ismail, Nazir Ahmed; Hoosen, Anwar Ahmed; Mehtar, Shaheen (International Federation of Infection Control (IFIC), 2010)Latex allergy is an important concern from an occupational safety aspect and affects compliance of glove usage, which directly influences infection control practices aimed at providing safe medical care for both the health ...
-
Beckert, Patrick; Sanchez-Padilla, Elisabeth; Merker, Matthias; Dreyer, Viola; Kohl, Thomas A.; Utpatel, Christian; Köser, Claudio U.; Barilar, Ivan; Ismail, Nazir Ahmed; Omar, Shaheed Vally; Klopper, Marisa; Warren, Robin M.; Hoffmann, Harald; Maphalala, Gugu; Ardizzoni, Elisa; De Jong, Bouke C.; Kerschberger, Bernhard; Schramm, Birgit; Andres, Sonke; Kranzer, Katharina; Maurer, Florian P.; Bonnet, Maryline; Niemann, Stefan (BioMed Central, 2020-12)BACKGROUND: Multidrug-resistant (MDR) Mycobacterium tuberculosis complex strains not detected by commercial molecular drug susceptibility testing (mDST) assays due to the RpoB I491F resistance mutation are threatening ...
-
Nelson, Kristin N.; Gandhi, Neel R.; Mathema, Barun; Lopman, Benjamin A.; Brust, James C.M.; Auld, Sara C.; Ismail, Nazir Ahmed; Omar, Shaheed Vally; Brown, Tyler S.; Allana, Salim; Campbell, Angie; Moodley, Pravi; Mlisana, Koleka; Shah, N. Sarita; Jenness, Samuel M. (Oxford University Press, 2020-07)Patterns of transmission of drug-resistant tuberculosis (TB) remain poorly understood, despite over half a million incident cases worldwide in 2017. Modeling TB transmission networks can provide insight into drivers of ...
-
Said, Halima Mohammed; Kock, Marleen M.; Ismail, Nazir Ahmed; Mphahlele, Matsie Theodora; Baba, Kamaldeen A.; Omar, Shaheed Vally; Osman, Ayman Gassim Elamin; Hoosen, Anwar Ahmed; Ehlers, Marthie Magdaleen (American Society for Microbiology, 2012-09)Despite South Africa being one of the high-burden multidrug-resistant tuberculosis (MDR-TB) countries, information regarding the population structure of drug-resistant Mycobacterium tuberculosis strains is limited from ...
-
Daum, Luke T.; Peters, Remco P.H.; Fourie, P.B. (Petrus Bernardus); Jonkman, K.; Worthy, Sue A.; Rodriguez, John D.; Ismail, Nazir Ahmed; Omar, Shaheed Vally; Fischer, Gerald W. (International Union Against Tuberculosis and Lung Disease, 2015-05)SETTING : Mopani District, South Africa. OBJECTIVE : To explore remote, molecular detection of Mycobacterium tuberculosis from sputum transported using PrimeStorew Molecular Transport Medium (PSMTM) compared to settings ...
-
Ismail, Nazir Ahmed; Said, H.M.; Rodrigues, C.; Omar, Shaheed Vally; Ajbani, K.; Sukhadiad, N.; Kohl, T.A.; Niemann, S.; Kranzer, K.; Diels, M.; Rigouts, L.; Rusch-Gerdes, S.; Siddiqi, S. (International Union Against Tuberculosis and Lung Disease, 2019-05)To conduct a multicentre study to establish the critical concentration (CC) for clofazimine (CFZ) for drug susceptibility testing (DST) of Mycobacterium tuberculosis on the MGIT™960™ system using the distribution of minimum ...
-
Kaniga, Koné; Cirillo, Daniela M.; Hoffner, Sven; Ismail, Nazir Ahmed; Kaur, Devinder; Lounis, Nacer; Metchock, Beverly; Pfyffer, Gaby E.; Venter, Amour (American Society for Microbiology, 2016-09)The aim of this study was to establish standardized drug susceptibility testing (DST) methodologies and reference MIC quality control (QC) ranges for bedaquiline, a diarylquinoline antimycobacterial, used in the treatment ...
-
Kaniga, Koné; Cirillo, Daniela M.; Hoffner, Sven; Ismail, Nazir Ahmed; Kaur, Devinder; Lounis, Nacer; Metchock, Beverly; Pfyffer, Gaby E.; Venter, Amour (American Society for Microbiology, 2016-12)OBJECTIVES : Our objective was to establish reference minimal inhibitory concentration (MIC) quality control (QC) ranges for drug susceptibility testing of antimycobacterials, including firstline agents, second-line ...
Now showing items 21-40 of 60