Browsing Research Articles (Medical Virology) by UP Author "Mans, Janet"

Browsing Research Articles (Medical Virology) by UP Author "Mans, Janet"

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  • Applicability of Bio-wipes for the collection of human faecal specimens for detection and characterisation of enteric viruses 
    Mans, Janet; Van Zyl, Walda B.; Taylor, Maureen B.; Page, Nicola Anne; Sobsey, M.D.; Barnard, T.G.; Potgieter, Natasha (Wiley, 2014-03)
    OBJECTIVE : To determine whether gastroenteritis viruses and other enteric viruses could be detected in faecal specimens collected with Bio-wipes. METHODS : Faecal specimens, self-collected with Bio-wipes, from 190 ...
  • Application of a competitive internal amplification control for the detection of sapoviruses in wastewater 
    Murray, Tanya Y.; Mans, Janet; Van Zyl, Walda B.; Taylor, Maureen B. (Springer, 2013-01)
    In this study, a competitive internal amplification control (IAC) was constructed for application in the real-time reverse transcription-polymerase chain reaction detection of sapoviruses (SaVs). A SaV RNA standard was ...
  • Diverse norovirus genotypes identified in sewage-polluted river water in South Africa 
    Mans, Janet; Netshikewta, Rembuluwani; Magwalivha, Mpho; Van Zyl, Walda B.; Taylor, Maureen B. (Cambridge University Press, 2012-03-21)
    This study aimed to assess norovirus (NoV) contamination and genotype diversity in surface water in Gauteng, South Africa. Between January 2008 and December 2010, three rivers, namely Klip, Suikerbosrant, and Rietspruit ...
  • Diversity of enteroviruses in cerebrospinal fluid specimens collected from hospitalised patients in the private and public sector in South Africa 
    Janse van Rensburg, Megan; Mans, Janet; Mafuyeka, Rendani T.; Strydom, Kathy-Anne; Myburgh, Marcelle; Van Zyl, Walda B. (Wiley, 2024-03)
    Enteroviruses cause a wide range of neurological illnesses such as encephalitis, meningitis, and acute flaccid paralysis. Two types of enteroviruses, echovirus E4 and E9, have recently been detected in South Africa and are ...
  • Emergence of a novel GII.17 norovirus – end of the GII.4 era? 
    De Graaf, M.; Van Beek, J.; Vennema, H.; Podkolzin, A.T.; Hewiit, J.; Bucardo, F.; Templeton, K.; Mans, Janet; Nordgren, J.; Reuter, Gunter; Lynch, M.; Rasmussen, L.D.; Iritani, N.; Chan, M.C.; Martella, V.; Ambert-Balay, K.; Vinje, J.; White, P.A.; Koopmans, M.P. (European Centre for Disease Prevention and Control, 2015-07-02)
    In the winter of 2014/15 a novel GII.P17-GII.17 norovirus strain (GII.17 Kawasaki 2014) emerged, as a major cause of gastroenteritis outbreaks in China and Japan. Since their emergence these novel GII.P17-GII.17 viruses ...
  • Emerging norovirus GII.4 2008 variant detected in hospitalised paediatric patients in South Africa 
    Mans, Janet; De Villiers, J.C. (Johanna Corrie); Du Plessis, Nicolette Marie; Avenant, Theunis Johannes; Taylor, Maureen B. (Elsevier, 2010-08)
    BACKGROUND: Noroviruses (NoVs)are important enteric pathogens that cause gastroenteritis worldwide. The first documented NoV outbreaks in South Africa(SA)were described in 1993. The current NoV prevalence and circulating ...
  • First detection of human sapoviruses in river water in South Africa 
    Murray, Tanya Y.; Mans, Janet; Taylor, Maureen B. (IWA Publishing, 2013)
    Over a 2-year period, from January 2009 to December 2010, water samples were collected from three rivers (Klip, Rietspruit and Suikerbosrand) in the Vaal River System, South Africa. Enteric viruses were recovered by a ...
  • FUT2 secretor status influences susceptibility to VP4 strain-specific rotavirus infections in South African children 
    MacDonald, Jaime Claire; Groome, Michelle J.; Janet, Janet; Page, Nicola Anne (MDPI, 2020-09)
    Gastroenteritis is a preventable cause of morbidity and mortality worldwide. Rotavirus vaccination has significantly reduced the disease burden, but the sub-optimal vaccine efficacy observed in low-income regions needs ...
  • Global spread of norovirus GII.17 Kawasaki 308, 2014–2016 
    Chan, Martin C.W.; Hu, Yunwen; Chen, Haili; Podkolzin, Alexander T.; Zaytseva, Ekaterina V.; Komano, Jun; Sakon, Naomi; Poovorawan, Yong; Vongpunsawad, Sompong; Thanusuwannasak, Thanundorn; Hewitt, Joanne; Croucher, Dawn; Collins, Nikail; Vinje, Jan; Pang, Xiaoli L.; Lee, Bonita E.; De Graaf, Miranda; Van Beek, Janko; Vennema, Harry; Koopmans, Marion P.G.; Niendorf, Sandra; Poljsak-Prijatelj, Mateja; Steyer, Andrej; White, Peter A.; Lun, Jennifer H.; Mans, Janet; Hung, Tin-Nok; Kwok, Kirsty; Cheung, Kelton; Lee, Nelson; Chan, Paul K.S. (Coordinating Center for Infectious Diseases, Centers for Disease Control and Prevention, 2017-08)
    Analysis of complete capsid sequences of the emerging norovirus GII.17 Kawasaki 308 from 13 countries demonstrated that they originated from a single haplotype since the initial emergence in China in late 2014. Global ...
  • Global trends in norovirus genotype distribution among children with acute gastroenteritis 
    Cannon, Jennifer L.; Bonifacio, Joseph; Bucardo, Filemon; Buesa, Javier; Bruggink, Leesa; Chan, Martin Chi-Wai; Fumian, Tulio M.; Giri, Sidhartha; Gonzalez, Mark D.; Hewitt, Joanne; Lin, Jih-Hui; Mans, Janet; Munoz, Christian; Pan, Chao-Yang; Pang, Xiao-Li; Pietsch, Corinna; Rahman, Mustafiz; Sakon, Naomi; Selvarangan, Rangaraj; Browne, Hannah; Barclay, Leslie; Vinje, Jan (Coordinating Center for Infectious Diseases, Centers for Disease Control and Prevention, 2021)
    Noroviruses are a leading cause of acute gastroenteritis (AGE) among adults and children worldwide. Noro- Surv is a global network for norovirus strain surveillance among children <5 years of age with AGE. Participants ...
  • Human calicivirus diversity in wastewater in South Africa 
    Murray, Tanya Y.; Mans, Janet; Taylor, Maureen B. (Wiley-Blackwell, 2013-06)
    AIM : To investigate the diversity of human caliciviruses (HuCVs) in wastewater from small- to medium-sized communities in five provinces of South Africa (SA). METHODS AND RESULTS : Wastewater samples (51) were screened ...
  • Human caliciviruses detected in HIV-seropositive children in Kenya 
    Mans, Janet; Murray, Tanya Y.; Kiulia, Nicholas M.; Mwenda, Jason M.; Musoke, Rachel N.; Taylor, Maureen B. (Wiley, 2014-01)
    The human caliciviruses (HuCVs) are important causes of gastroenteritis worldwide. Norovirus (NoV) and sapovirus (SaV) have been detected in HIV-seropositive children but the genetic diversity of HuCVs circulating in these ...
  • Multiple novel human norovirus recombinants identified in wastewater in Pretoria, South Africa by next-generation sequencing 
    Mabasa, V.V.; Van Zyl, W.B.; Ismail, Arshad; Allam, Mushal; Taylor, Maureen B.; Mans, Janet (MDPI, 2022-12-07)
    The genogroup II genotype 4 (GII.4) noroviruses are a major cause of viral gastroenteritis. Since the emergence of the Sydney_2012 variant, no novel norovirus GII.4 variants have been reported. The high diversity of ...
  • Norovirus epidemiology in South African children < 5 years hospitalised for diarrhoeal illness between 2009 and 2013 
    Page, Nicola Anne; Groome, M.J.; Nadan, Sandrama; Netshikweta, Rembuluwani; Keddy, Karen H.; Poonsamy, B.; Moyes, J.; Walaza, Sibongile; Kahn, K.; Madhi, S.A.; Taylor, Maureen B.; Mans, Janet; Cohen, C. (Cambridge University Press , 2017-07)
    Public health interest in norovirus (NoV) has increased in recent years following improved diagnostics, global burden estimates and the development of NoV vaccine candidates. This study aimed to describe the detection rate, ...
  • Norovirus genetic diversity in children under five years old with acute diarrhea in Mozambique (2014–2015) 
    Chilaule, Jorfelia J.; Munlela, Benilde; Mans, Janet; Mabasa, V.V.; Marques, Selma; Bauhofer, Adilson Fernando Loforte; Jane, Graziela; Anapakala, Elda; Oliveira, Fernanda; Cossa-Moiane, Idalecia; Guimaraes, Esperanca; Sambo, Julia; Bero, Diocreciano Matias; Chissaque, Assucenio; De Deus, Nilsa; Taylor, Maureen B. (MDPI, 2022-09-09)
    Norovirus (NoV) is the second most important cause of viral diarrheal disease in children worldwide after rotavirus and is estimated to be responsible for 17% of acute diarrhea in low-income countries. This study aimed ...
  • Norovirus GII.17 predominates in selected surface water sources in Kenya 
    Kiulia, Nicholas M.; Mans, Janet; Mwenda, J.M.; Taylor, Maureen B. (Springer, 2014-12)
    In this study, the prevalence and genotypes of noroviruses (NoVs) in selected water sources from rural, urban and refugee settings in Kenya were investigated. Ten litres each of river, household and borehole water ...
  • Norovirus infections and disease in lower‐middleand low‐income countries, 1997–2018 
    Mans, Janet (MDPI, 2019)
    Noroviruses are a major cause of viral gastroenteritis. The burden of the norovirus in low-resource settings is not well-established due to limited data. This study reviews the norovirus prevalence, epidemiology, and ...
  • Novel norovirus recombinants detected in South Africa 
    Mans, Janet; Murray, Tanya Y.; Taylor, Maureen B. (BioMed Central, 2014-09-17)
    BACKGROUND: Noroviruses (NoV) are the leading cause of viral gastroenteritis worldwide. Recombination frequently occurs within and between NoV genotypes and recombinants have been implicated in sporadic cases, outbreaks and ...
  • The role of wastewater-based epidemiology for SARS-CoV-2 in developing countries : cumulative evidence from South Africa supports sentinel site surveillance to guide public health decision-making 
    Iwu-Jaja, Chinwe Juliana; Ndlovu, Nkosenhle Lindo; Rachida, Said; Yousif, Mukhlid; Taukobong, Setshaba; Macheke, Mokgaetji; Mhlanga, Laurette; Van Schalkwyk, Cari; Pulliam, Juliet R.C.; Moultrie, Tom; Le Roux, Wouter; Schaefer, Lisa; Pocock, Gina; Coetzee, Leanne Z.; Mans, Janet; Bux, Faizal; Pillay, Leanne; De Villiers, Dariah; Du Toit, A.P.; Jambo, Don; Gomba, Annancietar; Groenink, Shaun; Madgewick, Neil; Van der Walt, Martie; Mutshembele, Awelani; Berkowitz, Natascha; Suchard, Melinda S.; McCarthy, Kerrigan M. (Elsevier, 2023-12)
    The uptake of wastewater-based epidemiology (WBE) for SARS-CoV-2 as a complementary tool for monitoring population-level epidemiological features of the COVID-19 pandemic in low-and-middle-income countries (LMICs) is low. ...
  • Structure and function of murine cytomegalovirus MHC-I-like molecules : how the virus turned the host defense to its advantage 
    Mans, Janet; Zhi, Li; Revilleza, Maria Jamela R.; Smith, Lee; Redwood, Alec; Natarajan, Kannan; Margulies, David H. (Springer, 2009)
    The mouse cytomegalovirus (CMV), a β-herpesvirus, exploits its large (~230 kb) double-stranded DNA genome for both essential and non-essential functions. Among the non-essential functions are those that offer the virus a ...