Browsing Research Articles (Medical Virology) by Title

Browsing Research Articles (Medical Virology) by Title

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  • The impact of influenza and tuberculosis interaction on mortality among individuals aged >= 15 years hospitalized with severe respiratory illness in South Africa, 2010-2016 
    Walaza, Sibongile; Tempia, Stefano; Dawood, Halima; Variava, Ebrahim; Wolter, Nicole; Dreyer, Andries; Moyes, Jocelyn; Von Mollendorf, Claire; McMorrow, Meredith; Von Gottberg, Anne; Haffejee, Sumayya; Venter, Marietjie; Treurnicht, Florette K.; Hellferscee, Orienka; Martinson, Neil A.; Ismail, Nazir Ahmed; Cohen, Cheryl (Oxford University Press, 2019-03)
    BACKGROUND: Data on the prevalence and impact of influenza–tuberculosis coinfection on clinical outcomes from high–HIV and –tuberculosis burden settings are limited. We explored the impact of influenza and tuberculosis ...
  • Impact of lamivudine-based antiretroviral treatment on hepatitis B viremia in HIV-coinfected South Africans 
    Lukhwareni, Azwidowi; Gededzha, Maemu Petronella; Amponsah-Dacosta, Edina; Blackard, Jason T.; Burnett, Rosemary J.; Selabe, Selokela Gloria; Kyaw, Thanda; Mphahlele, M. Jeffrey (MDPI Publishing, 2020-06)
    This prospective study investigated the impact of lamivudine-containing antiretroviral therapy (ART) on HIV-positive patients in South Africa with baseline hepatitis B virus (HBV) infection. Follow-up samples from 56 ...
  • Incidence of Sindbis virus in hospitalized patients with acute fevers of unknown cause in South Africa, 2019–2020 
    Meno, Kgothatso Debra; Yah, Clarence S.; Mendes, Adriano; Venter, Marietjie (Frontiers Media SA, 2022-02-07)
    BACKGROUND : Sindbis virus (SINV) is a mosquito-borne alphavirus that is widely distributed worldwide. Little is known about the febrile and neurological disease burden due to SINV in South Africa. PATIENTS AND METHODS ...
  • Influenza surveillance in 15 countries in Africa, 2006-2010 
    Radin, Jennifer Michalove; Katz, Mark A.; Tempia, Stefano; Nzussouo, Ndahwouh Talla; Davis, Richard; Duque, Jazmin; Adedeji, Adebayo; Adjabeng, Michael Jeroen; Ampofo, William Kwabena; Ayele, Workenesh; Bakamutumaho, Barnabas; Barakat, Amal; Benmamoun, Abderahman; Cohen, Adam L.; Cohen, Cheryl; Dalhatu, Ibrahim T.; Daouda, Coulibaly; Dueger, Erica; Francisco, Moisés; Heraud, Jean-Michel; Jima, Daddi; Kabanda, Alice; Kadjo, Hervé; Kandeel, Amr; Shamamba, Stomy Karhemere Bi; Kasolo, Francis; Kronmann, Karl C.; Liwewe, Mazyanga L. Mazaba; Lutwama, Julius Julian; Matonya, Miriam; Mmbaga, Vida; Mott, Joshua A.; Muhimpundu, Marie Aimee; Muthoka, Phillip; Njuguna, Henry; Randrianasolo, Laurence; Refaey, Samir; Sanders, Charlene; Talaat, Maha; Theo, Andros; Valente, Fátima; Venter, Marietjie; Woodfill, Celia; Bresee, Joseph; Moen, Ann; Widdowson, Marc-Alain (Oxford University Press, 2012)
    BACKGROUND: In response to the potential threat of an influenza pandemic, several international institutions and governments, in partnership with African countries, invested in the development of epidemiologic and laboratory ...
  • Influenza vaccination of pregnant women and protection of their infants 
    Madhi, Shabir A.; Cutland, Clare L.; Kuwanda, Locadiah; Weinberg, Adriana; Hugo, Andrea; Jones, Stephanie; Adrian, Peter V.; Van Niekerk, Nadia; Treurnicht, Florette K.; Ortiz, Justin R.; Venter, Marietjie; Violari, Avy; Neuzil, Kathleen M.; Simoes, Eric A.F.; Klugman, Keith P.; Nunes, Marta C. (Massachusetts Medical Society, 2014)
    BACKGROUND There are limited data on the efficacy of vaccination against confirmed influenza in pregnant women with and those without human immunodeficiency virus (HIV) infection and protection of their infants. METHODS We ...
  • Influenza viral shedding in a prospective cohort of HIV-infected and uninfected children and adults in 2 provinces of South Africa, 2012-2014 
    Von Mollendorf, Claire; Hellferscee, Orienka; Valley-Omar, Ziyaad; Treurnicht, Florette K.; Walaza, Sibongile; Martinson, Neil A.; Lebina, Limakatso; Mothlaoleng, Katlego; Mahlase, Gethwana; Variava, Ebrahim; Cohen, Adam L.; Venter, Marietjie; Cohen, Cheryl; Tembo, Stefano (Oxford University Press, 2018-10)
    BACKGROUND : Prolonged shedding of influenza viruses may be associated with increased transmissibility and resistance mutation acquisition due to therapy. We compared duration and magnitude of influenza shedding between ...
  • Influenza virus infection is associated with increased risk of death amongst patients hospitalized with confirmed pulmonary tuberculollsis in South Africa, 2010-2011 
    Walaza, Sibongile; Tempia, Stefano; Dawood, Halima; Variava, Ebrahim; Moyes, Jocelyn; Cohen, Adam L.; Wolter, Nicole; Groome, Michelle; Von Mollendorf, Claire; Kahn, Kathleen; Pretorius, Marthi Andréa; Venter, Marietjie; Madhi, Shabir A.; Cohen, Cheryl (BioMed Central, 2015-01)
    BACKGROUND : Data on the association between influenza and tuberculosis are limited. We describe the characteristics of patients with laboratory-confirmed tuberculosis, laboratory-confirmed influenza and tuberculosis-influenza ...
  • Integrative taxonomic analysis of new collections from the central Angolan highlands resolves the taxonomy of African pipistrelloid bats on a continental scale 
    Taylor, Peter John; Strydom, Erika; Richards, Leigh; Markotter, Wanda; Toussaint, Dawn Cory; Kearney, Teresa; Cotterill, F.P.D. (Woody); Howard, Alexandra; Weier, Sina Monika; Keith, Mark; Neef, Gotz; Mamba, Mnqobi L.; Magagula, Siphesihle; Monadjem, Ara (Oxford University Press, 2022-12)
    Ten years ago, the genus-level and species-level taxonomy of African pipistrelloid bats was in a state of flux. In spite of advances in the past decade, gaps in collecting from species-rich regions like Angola have hampered ...
  • An investigation of culicoides (Diptera: Ceratopogonidae) as potential vectors of medically and veterinary important arboviruses in South Africa 
    Snyman, Jumari; Venter, Gert J.; Venter, Marietjie (MDPI, 2021-10)
    Culicoides-borne viruses such as bluetongue, African horse sickness, and Schmallenberg virus cause major economic burdens due to animal outbreaks in Africa and their emergence in Europe and Asia. However, little is known ...
  • Investigation of two suspected diarrhoeal-illness outbreaks in Northern Cape and KwaZulu-Natal provinces, South Africa, April–July 2013 : the role of rotavirus 
    Shonhiwa, Andronica Moipone; Ntshoe, Genevie M.; Crisp, Noreen; Olowolagba, Ayo J.; Mbuthu, Vusi; Taylor, Maureen B.; Thomas, Juno; Page, Nicola Anne (AOSIS, 2020-07-22)
    BACKGROUND : Suspected diarrhoeal-illness outbreaks affecting mostly children < 5 years were investigated between May and July 2013 in Northern Cape province (NCP) and KwaZulu-Natal (KZN) province. This study describes ...
  • Isolation of a novel orthobunyavirus from bat flies (Eucampsipoda africana) 
    Jansen van Vuren, Petrus; Wiley, Michael R.; Palacios, Gustavo; Storm, Nadia; Markotter, Wanda; Birkhead, Monica; Kemp, Alan; Paweska, Janusz Tadeusz (Microbiology Society, 2017-05)
    The Bunyaviridae family comprises viruses causing diseases of public and veterinary health importance, including viral haemorrhagic and arboviral fevers. We report the isolation, identification and genome characterization ...
  • Laboratory considerations for reporting cycle threshold value in COVID-19 
    Punchoo, Rivak; Bhoora, Sachin; Bangalee, Avania (International Federation of Clinical Chemistry and Laboratory Medicine, 2022-08)
    The Coronavirus Disease 2019 (COVID-19) pandemic is caused by the SARS-CoV-2 RNA virus. Nucleic acid amplification testing (NAAT) is the mainstay to confirm infection. A large number of reverse transcriptase polymerase ...
  • Large-scale international validation of an indirect ELISA based on recombinant nucleocapsid protein of rift valley fever virus for the detection of IgG antibody in domestic ruminants 
    Paweska, Janusz Tadeusz; Jansen van Vuren, Petrus; Msimang, Veerle; Lo, Modu Moustapha; Thiongane, Yaya; Mulumba-Mfumu, Leopold K.; Mansoor, Alqadasi; Fafetine, Jose M.; Magona, Joseph W.; Boussini, Hiver; Bazanow, Barbara; Wilson, William C.; Pepin, Michel; Unger, H.; Viljoen, Gerrit (MDPI, 2021-08)
    Diagnostic performance of an indirect enzyme-linked immunosorbent assay (I-ELISA) based on a recombinant nucleocapsid protein (rNP) of the Rift Valley fever virus (RVFV) was validated for the detection of the IgG antibody ...
  • Leveraging the Global Influenza Surveillance and Response System for global respiratory syncytial virus surveillance-opportunities and challenges 
    Broor, Shobha; Campbell, Harry; Hirve, Siddhivinayak; Hague, Siri; Jackson, Sandra; Moen, Ann; Nair, Harish; Palekar, Rakhee; Rajatonirina, Soatiana; Smith, Peter G.; Venter, Marietjie; Wairagkar, Niteen; Zambon, Maria; Ziegler, Thedi; Zhang, Wenqing (Wiley Open Access, 2020-11)
    BACKGROUND : Respiratory syncytial virus (RSV)‐associated acute lower respiratory infection is a common cause for hospitalization and hospital deaths in young children globally. There is urgent need to generate evidence ...
  • Leveraging the Road to Health booklet as a unique patient identifier to monitor the prevention of mother-to-child transmission programme 
    Mazanderani, Ahmad Haeri; Sherman, G.G.; Moyo, F.; Goga, Ameena Ebrahim; Feucht, Ute Dagmar (Health and Medical Publishing Group, 2018-09)
    BACKGROUND. Currently there is no unique patient identification system in the South African public health sector. Therefore, routine laboratory data cannot effectively be de-duplicated, thereby hampering surveillance of ...
  • Lineage 2 West Nile virus as cause of fatal neurologic disease in horses, South Africa 
    Venter, Marietjie; Human, Stacey; Zaayman, Dewald; Gerdes, Gertruida Hermanna; Williams, June Heather; Steyl, Johan Christian Abraham; Leman, Patricia A.; Paweska, Janusz Tadeusz; Setzkorn, Hildegard; Rous, Gavin; Murray, Sue; Parker, Rissa; Donnellan, Cynthia Mary Bridget; Swanepoel, Robert (Coordinating Center for Infectious Diseases, Centers for Disease Control and Prevention, 2009-05-06)
    Serologic evidence suggests that West Nile virus (WNV) is widely distributed in horses in Southern Africa. However, because few neurologic cases have been reported, endemic lineage 2 strains were postulated to be non-pathogenic ...
  • Living donor liver transplant from an HIV-positive mother to her HIV-negative child : opening up new therapeutic options 
    Botha, Jean; Conradie, Francesca; Etheredge, Harriet; Fabian, June; Duncan, Mary; Mazanderani, Ahmad Haeri; Paximadis, Maria; Maher, Heather; Russell Britz; Loveland, Jerome; Strobele, Bernd; Rambarran, Sharan; Mahomed, Adam; Terblanche, Alta J.; Beretta, Marisa; Brannigan, Liam; Pienaar, Michael; Archibald-Durham, Lindsay; Lang, Allison; Tiemessen, Caroline T. (Lippincott Williams and Wilkins, 2018)
    OBJECTIVE : Transplant a liver from an HIV-positive mother to her HIV-negative child to save the child’s life. DESIGN : A unique case of living donor liver transplantation from an HIV-positive mother to her HIV-negative ...
  • Loss of detectability and indeterminate results : challenges facing HIV infant diagnosis in South Africa's expanding ART programme 
    Haeri Mazanderani, Ahmad F.; Du Plessis, Nicolette Marie; Thomas, Winifred Nancy; Venter, E.; Avenant, Theunis Johannes (Health and Medical Publishing Group, 2014-08)
    BACKGROUND. Early infant diagnosis with rapid access to treatment has been found to reduce HIV-associated infant mortality and morbidity considerably. In line with international standards, current South African guidelines ...
  • Loss to follow-up in a community clinic in South Africa – roles of gender, pregnancy and CD4 count 
    Wang, Bingxia; Losina, Elena; Stark, Ruth; Munro, Alison; Walensky, Rochelle P.; Wilke, Marisa; Martin, Desmond J.; Lu, Zhigang; Freedberg, Kenneth A.; Wood, Robin (Health and Medical Publishing Group, 2011-04)
    BACKGROUND: Faith-based organisations have expanded antiretroviral therapy (ART) in community clinics across South Africa. Loss to follow-up (LTFU), however, limits the potential individual and population treatment benefits ...
  • Low seroprevalence of hepatitis E virus in pregnant women in an urban area near Pretoria, South Africa 
    Simani, Omphile E.; Seipone, Tshegofatso P.; Selabe, Gloria; Seheri, L. Mapaseka; Mphahlele, M.; Mayaphi, Simnikiwe Horatious; Steele, A. Duncan (Elsevier, 2022-03)
    OBJECTIVES : Hepatitis E virus (HEV) infection is a globally neglected health problem with a high burden in resource-poor communities. Pregnant women are at increased risk of complications. This pilot study sought to assess ...