The members of the genus Thermoactinomyces are known for their protein degradative capacities. Thermoactinomyces
sp. strain AS95 is a Gram-positive filamentous bacterium, isolated from moderately saline water in the Thamelaht
region of Algeria. This isolate is a thermophilic aerobic bacterium with the capacity to produce extracellular proteolytic
enzymes. This strain exhibits up to 99 % similarity with members of the genus Thermoactinomyces, based on 16S rRNA
gene sequence similarity. Here we report on the phenotypic features of Thermoactinomyces sp. strain AS95 together
with the draft genome sequence and its annotation. The genome of this strain is 2,558,690 bp in length (one
chromosome, but no plasmid) with an average G + C content of 47.95 %, and contains 2550 protein-coding
and 60 RNA genes together with 64 ORFs annotated as proteases.