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Browsing Research Articles (Medical Oncology) by Subject "Breast cancer"

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Breast cancer in low-middle income countries : abnormality in splicing and lack of targeted treatment options

Francies, Flavia Zita; Hull, Rodney; Khanyile, Richard; Dlamini, Zodwa (e-Century Publishing, 2020-05)

Breast cancer is a common malignancy among women worldwide. Regardless of the economic status of a country, breast cancer poses a burden in prevention, diagnosis and treatment. Developed countries such as the U.S. have ...
Combination of everolimus with trastuzumab plus paclitaxel as first-line treatment for patients with HER2-positive advanced breast cancer (BOLERO-1) : a phase 3, randomised, double-blind, multicentre trial

Hurvitz, Sara A.; Andre, Fabrice; Jiang, Zefei; Shao, Zhimin; Mano, Max S.; Neciosup, Silvia P.; Tseng, Ling-Min; Zhang, Qingyuan; Shen, Kunwei; Liu, Donggeng; Dreosti, Lydia M.; Burris, Howard A.; Toi, Masakazu; Buyse, Marc E.; Cabaribere, David; Lindsay, Mary-Ann; Rao, Shantha; Pacaud, Lida Bubuteishvili; Taran, Tetiana; Slamon, Dennis (Elsevier, 2015-07)

BACKGROUND : mTOR inhibition has been shown to reverse trastuzumab resistance from hyperactivated the PIK/AKT/mTOR pathway due to PTEN loss, by sensitizing PTEN-deficient tumors towards trastuzumab. The BOLERO-1 study ...
The integrative bioinformatics approaches to predict the xanthohumol as anti-breast cancer molecule : targeting cancer cells signaling PI3K and AKT kinase pathway

Gupta, Kartikey Kumar; Sharma, Kamal Kant; Chandra, Harish; Panwar, Himalaya; Bhardwaj, Nitin; Altwaijry, Najla A.; Alsfouk, Aisha A.; Dlamini, Zodwa; Afzal, Obaid; Altamimi, Abdulmalik S.A.; Khan, Shahanavaj; Mishra, Abhay Prakash (Frontiers Media S.A., 2022-12)

BACKGROUND : Breast cancer is the most common type of cancer in women, and vast research is being conducted throughout the world for the treatment of this malignancy by natural products using various computational approaches. ...

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Browsing Research Articles (Medical Oncology) by Subject "Breast cancer"

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