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Bacterial secretion system functions : evidence of interactions and downstream implications
Maphosa, Silindile; Moleleki, Lucy N.; Motaung, Thabiso Eric
Unprecedented insights into the biology and functions of bacteria have been and continue to be gained through studying bacterial
secretion systems in isolation. This method, however, results in our understanding of the systems being primarily based on
the idea that they operate independently, ignoring the subtleties of downstream interconnections. Gram-negative
bacteria are
naturally able to adapt to and navigate their frequently varied and dynamic surroundings, mostly because of the covert connections
between secretion systems. Therefore, to comprehend some of the linked downstream repercussions for organisms that
follow this discourse, it is vital to have mechanistic insights into how the intersecretion system functions in bacterial rivalry,
virulence, and survival, among other things. To that purpose, this paper discusses a few key instances of molecular antagonistic
and interdependent relationships between bacterial secretion systems and their produced functional products.