Therapeutic hypothermia for neonatal hypoxic ischaemic encephalopathy should not be discontinued in low- and middle-income countries
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Date
Authors
Ballot, Daynia E.
Ramdin, Tanusha D.
Bandini, Rossella M.
Nakwa, Firdose
Velaphi, Sithembiso
Coetzee, Melantha
Masemola, Khomotso
Kali, Gugulabatembunamahlubi J.D.
Horn, Alan R.
Pillay, Shakti
Journal Title
Journal ISSN
Volume Title
Publisher
Health and Medical Publishing Group
Abstract
Perinatal asphyxia is a major cause of death and disability in
children. Therapeutic hypothermia (TH) has become a standard
of care for newborn infants who have sustained hypoxic ischaemic
encephalopathy (HIE) due to perinatal asphyxia. There is compelling
evidence to support this approach. A Cochrane systematic review of
11 prospective randomised controlled trials including 1 505 newborns
showed that TH started within 6 hours of birth in infants with HIE
significantly decreased mortality and neurodevelopmental disability
in survivors.
Description
Keywords
Therapeutic hypothermia, Hypothermia, Neonatal, Low- and middle-income countries (LMICs), Perinatal asphyxia, Children, Hypoxic ischaemic encephalopathy (HIE)
Sustainable Development Goals
Citation
Ballot, D.E., Ramdin, T.D., Bandini, R.M. et al. Therapeutic hypothermia for neonatal hypoxic ischaemic encephalopathy should not be discontinued in low- and middle-income countries. South African Medical Journal, vol. 111, no. 12, pp. 1168-1169, dec. 2021. doi:10.7196/SAMJ.2021.v111i12.16180.