Therapeutic hypothermia for neonatal hypoxic ischaemic encephalopathy should not be discontinued in low- and middle-income countries

dc.contributor.authorBallot, Daynia E.
dc.contributor.authorRamdin, Tanusha D.
dc.contributor.authorBandini, Rossella M.
dc.contributor.authorNakwa, Firdose
dc.contributor.authorVelaphi, Sithembiso
dc.contributor.authorCoetzee, Melantha
dc.contributor.authorMasemola, Khomotso
dc.contributor.authorKali, Gugulabatembunamahlubi J.D.
dc.contributor.authorHorn, Alan R.
dc.contributor.authorPillay, Shakti
dc.contributor.authorVan Rensburg, Jeanne
dc.contributor.authorPepper, Michael Sean
dc.date.accessioned2022-10-18T04:41:31Z
dc.date.available2022-10-18T04:41:31Z
dc.date.issued2021-12
dc.description.abstractPerinatal asphyxia is a major cause of death and disability in children. Therapeutic hypothermia (TH) has become a standard of care for newborn infants who have sustained hypoxic ischaemic encephalopathy (HIE) due to perinatal asphyxia. There is compelling evidence to support this approach. A Cochrane systematic review of 11 prospective randomised controlled trials including 1 505 newborns showed that TH started within 6 hours of birth in infants with HIE significantly decreased mortality and neurodevelopmental disability in survivors.en_US
dc.description.departmentImmunologyen_US
dc.description.departmentPaediatrics and Child Healthen_US
dc.description.librariandm2022en_US
dc.description.urihttp://www.samj.org.zaen_US
dc.identifier.citationBallot, D.E., Ramdin, T.D., Bandini, R.M. et al. Therapeutic hypothermia for neonatal hypoxic ischaemic encephalopathy should not be discontinued in low- and middle-income countries. South African Medical Journal, vol. 111, no. 12, pp. 1168-1169, dec. 2021. doi:10.7196/SAMJ.2021.v111i12.16180.en_US
dc.identifier.issn2078- 5135 (online)
dc.identifier.issn0256-9574 (print)
dc.identifier.other10.7196/SAMJ.2021.v111i12.16180
dc.identifier.urihttps://repository.up.ac.za/handle/2263/87763
dc.language.isoenen_US
dc.publisherHealth and Medical Publishing Groupen_US
dc.rightsThis open-access article is distributed under Creative Commons licence CC-BY-NC 4.0.en_US
dc.subjectTherapeutic hypothermiaen_US
dc.subjectHypothermiaen_US
dc.subjectNeonatalen_US
dc.subjectLow- and middle-income countries (LMICs)en_US
dc.subjectPerinatal asphyxiaen_US
dc.subjectChildrenen_US
dc.subjectHypoxic ischaemic encephalopathy (HIE)en_US
dc.titleTherapeutic hypothermia for neonatal hypoxic ischaemic encephalopathy should not be discontinued in low- and middle-income countriesen_US
dc.typeArticleen_US

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