Browsing South African National Veterinary Repository by Author "Schultz, R.A. (Rowena Anitra)"

Browsing South African National Veterinary Repository by Author "Schultz, R.A. (Rowena Anitra)"

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  • Cardiac glycoside poisoning in sheep caused by Urginea physodes (Jacq.) Bak. and the isolated physodine A 
    Nel, P.W.; Jordaan, P.; Anderson, L.A.P.; Kellerman, T. Stephanus; Reid, Clare; Schultz, R.A. (Rowena Anitra); Bigalke, R.D. (Published by the Government Printer, Pretoria., 1987)
    Urginea physodes (Jacq.) Bak., a species closely related to or possibly synonymous with U. pusilla, is described and its distribution given. Four bufadienolides were isolated from U. physodes and the approximated LD₅₀ and ...
  • Clinical pathological changes in gousiekte, a plant-induced cardiotoxicosis of ruminants 
    Prozesky, Leon; Fourie, Niel; Kellerman, T. Stephanus; Labuschagne, Leonie; Schultz, R.A. (Rowena Anitra); Verwoerd, Daniel Wynand (Published by the Government Printer, Pretoria., 1989)
    Twenty sheep were dosed with either Pachystigma pygmaeum or Fadogia homblei belonging to the Rubiaceae. The experimentally-induced cardiotoxicoses were monitored by various clinical pathological parameters and heart ...
  • Conditioned feed aversion as a means to prevent tulp (Homeria pallida) poisoning in cattle 
    Snyman, Leendert D.; Schultz, R.A. (Rowena Anitra); Joubert, J.P.J.; Basson, Karin M.; Labuschagne, Leonie; Boomker, Jacob Diederik Frederik (Published jointly by the Agricultural Research Council, ARC-Onderstepoort Veterinary Institute and the Faculty of Veterinary Science, University of Pretoria., 2003)
    Conditioned feed aversion was investigated as a means to prevent tulp (Homeria pallida) poisoning in cattle on tulp-infested grazing. Aversion treatment with a combination of epoxyscillirosidin and lithium chloride together ...
  • Continuous exposure to an aversive mixture as a means of maintaining aversion to vermeerbos (Geigeria ornativa O. Hoffm.) in the presence of non-averted sheep 
    Snyman, Leendert D.; Schultz, R.A. (Rowena Anitra); Kellerman, T. Stephanus; Labuschagne, Leonie; Boomker, Jacob Diederik Frederik (Published jointly by the Agricultural Research Council, ARC-Onderstepoort Veterinary Institute and the Faculty of Veterinary Science, University of Pretoria., 2002)
    Continuous exposure to an aversive mixture was investigated as a means of maintaining aversion to vermeerbos in sheep subjected to the social influence of non-averted sheep. The use of an aversive mixture was based on a ...
  • Effect of pavetamine on protein synthesis in rat tissue 
    Prozesky, Leon; Schultz, R.A. (Rowena Anitra); Fourie, Niel; Basson, Karin M.; Labuschagne, Leonie; Boomker, Jacob Diederik Frederik (Published jointly by the Agricultural Research Council, ARC-Onderstepoort Veterinary Institute and the Faculty of Veterinary Science, University of Pretoria., 2001)
    Pavetamine, the active principle of plants causing gousiekte in ruminants, was found in this study to be an inhibitor of protein synthesis in the rat heart. Sprague-Dawley rats were injected intra-peritoneally with 8-10 ...
  • The efficacy of acetamide for the treatment of experimental Dichapetalum cymosum (gifblaar) poisoning in sheep 
    Egyed, M.N.; Schultz, R.A. (Rowena Anitra); Bigalke, R.D. (Published by the Government Printer, Pretoria., 1986)
    High mortality of livestock is caused annually by the plant, Dichapetalum cymosum (gifblaar), in the Northern Transvaal. So far no therapeutic measures have been developed for the prevention or treatment of this poisoning. ...
  • An electrocardiographic study of normal goats and cattle using a modified technique 
    Schultz, R.A. (Rowena Anitra); Pretorius, P.J.; De Kock, V.E.; De Lange, M.; Bigalke, R.D.; Howell, P.G.; Reinecke, R.K.; Walker, Jane B. (Published by the Government Printer, Pretoria, 1972)
    An electrocardiographic technique, developed in sheep in the standing position, was applied to normal cattle and goats. Recordings were made with Einthoven's triangle in the sagittal plane and with the electrodes in rigidly ...
  • An electrocardiographic study of normal sheep using a modified technique 
    Schultz, R.A. (Rowena Anitra); Pretorius, P.J.; Terblanche, M.; De Kock, V.E.; De Lange, M.; Bigalke, R.D.; Howell, P.G.; Reinecke, R.K.; Walker, Jane B. (Published by the Government Printer, Pretoria, 1972)
    A technique was developed which allowed a reproducible electrocardiogram to be recorded in normal sheep. Einthoven's triangle was moved to the sagittal plane and the needle electrodes were positioned at fixed points. Six ...
  • Experimental evidence that the active principle of the poisonous plant Thesium lineatum L.f. (Santalaceae) is a bufadienolide 
    Anderson, L.A.P.; Joubert, J.P.J.; Kellerman, T. Stephanus; Pienaar, Barendina J.; Schultz, R.A. (Rowena Anitra); Bigalke, R.D. (Published by the Government Printer, Pretoria., 1987)
    The toxicity of Thesium lineatum is confirmed in sheep. A toxic crystalline bufadienolide, with the suggested trivial name thesiuside, has been isolated from it. This is the first cardiac glycoside to be isolated from ...
  • The experimental production of krimpsiekte in sheep with Tylecodon grandiflorus (Burm.f.) Toelken and some of its bufadienolides. 
    Prozesky, Leon; Anderson, L.A.P.; Joubert, J.P.J.; Kellerman, T. Stephanus; Schultz, R.A. (Rowena Anitra); Procos, J.; Olivier, Philippa M.; Bigalke, R.D. (Published by The Government Printer, Pretoria, 1983)
    Six bufadienolides were isolated from Tylecodon grandiflorus (Burm. f.) Toelken. The paretic syndrome, krimpsiekte, could be induced in sheep either by repeated oral administration of small quantities of plant material or ...
  • Galenia africana L. poisoning in sheep and goats : hepatic and cardiac changes 
    Van der Lugt, Jaco J.; Schultz, R.A. (Rowena Anitra); Fourie, Niel; Hon, L.J.; Jordaan, P.; Labuschagne, Leonie; Verwoerd, Daniel Wynand (Published by the Agricultural Research Council, Onderstepoort Veterinary Institute., 1992)
    Lesions in 4 field cases (3 sheep and 1 goat) of 'waterpens' or water belly, caused by the plant Galenia africana, are described. The clinical pathological and pathological findings in 7 sheep which were drenched with ...
  • In vivo effects of a novel calcium antagonist (R56865) against induced epoxyscillirosidin and tulp poisoning in sheep 
    Swan, Gerry E.; Schultz, R.A. (Rowena Anitra); Kellerman, T. Stephanus; Mulders, M.S.G.; Maartens, B.P.; Van der Walt, J.J.; Verwoerd, Daniel Wynand (Published by the Agricultural Research Council, Onderstepoort Veterinary Institute, 1995)
    Two anaesthetized sheep were intoxicated with epoxyscillirosidin, the main cardio-active bufadienolide, extracted from Homeria pallida (Natal yellow tulp). The epoxyscillirosidin was injected intravenously as a bolus of ...
  • Isolation and characterization of and some observations on poisoning by bufadienolides from Cotyledon orbiculata L. var. orbiculata 
    Prozesky, Leon; Anderson, L.A.P.; Schultz, R.A. (Rowena Anitra); Kellerman, T. Stephanus; Kotze, S.M.; Erasmus, G.L.; Labuschagne, Leonie; Bigalke, R.D. (Published by the Government Printer, Pretoria., 1985)
    The approximate LD₅₀ and cumulative effect of 4 bufadienolides, isolated from Cotyledon orbiculata, were determined in guinea-pigs. Two of the bufadienolides proved to be mildly cumulative. One of the mildly cumulative ...
  • Isolation of the toxin responsible for gousiekte, a plant-induced cardiomyopathy of ruminants in southern Africa 
    Prozesky, Leon; Fourie, Niel; Erasmus, G.L.; Schultz, R.A. (Rowena Anitra); Verwoerd, Daniel Wynand (Published by the Agricultural Research Council, Onderstepoort Veterinary Institute, 1995)
    Gousiekte was induced in sheep and goats by the oral and intravenous (i/v) administration of methanolic and ethanolic precipitates of aqueous extracts of Pavetta harborii. Further purification of the toxic principle was ...
  • Krimpsiekte and acute cardiac glycoside poisoning in sheep caused by bufadienolides from the plant Kalanchoe lanceolata Forsk 
    Prozesky, Leon; Anderson, L.A.P.; Schultz, R.A. (Rowena Anitra); Joubert, J.P.J.; Kellerman, T. Stephanus; Erasmus, G.L.; Procos, J.; Bigalke, R.D. (Published by The Government Printer, Pretoria, 1983)
    Three toxic bufadienolides, one characterized as hellibrigenin 3-acetate, have been isolated from Kalanchoe lanceolata Forsk. Typical signs of cardiac glycoside poisoning, involving the gastro-intestinal, neuromuscular ...
  • Krimpsiekte in a sheep following a single dose of Tylecodon ventricosus (Burm. f.) Toelken and the isolation of tyledoside D from this plant species 
    Vleggaar, Robert; Botha, C.J. (Christoffel Jacobus); Kellerman, T. Stephanus; Schultz, R.A. (Rowena Anitra); Erasmus, G.L.; Retief, E.P.; Verwoerd, Daniel Wynand (Published by the Agricultural Research Council, Onderstepoort Veterinary Institute, 1998)
    Tylecodon ventricosus induced severe respiratory distress in two penned sheep without any electrocardiographic abnormalities being recorded. Based on the results it appears as if T. ventricosus predominantly induces the ...
  • Krimpsiekte, associated with thalamic lesions, induced by the neurotoxic cardiac glycoside, cotyledoside, isolated from Tylecodon wallichii (Harv.) Toelken subsp. wallichii 
    Vleggaar, Robert; Botha, C.J. (Christoffel Jacobus); Van der Lugt, Jaco J.; Erasmus, G.L.; Kellerman, T. Stephanus; Schultz, R.A. (Rowena Anitra); Verwoerd, Daniel Wynand (Published by the Agricultural Research Council, Onderstepoort Veterinary Institute, 1997)
    The specific neurotoxic principle of Tylecodon wallichii (Harv.) Toelken subsp. wallichii, the cause of krimpsiekte in small stock, was isolated and identified as the previously described cumulative bufadienolide, cotyledoside. ...
  • Neurotoxicity in calves induced by the plant, Nierembergia hippomanica Miers var. violacea Millan in South Africa 
    Botha, C.J. (Christoffel Jacobus); Schultz, R.A. (Rowena Anitra); Van der Lugt, Jaco J.; Retief, E.; Labuschagne, Leonie; Verwoerd, Daniel Wynand (Published by the Agricultural Research Council, Onderstepoort Veterinary Institute, 1999)
    The plant Nierembergia hippomanica var. violacea has been incriminated in field outbreaks of neurotoxicity in calves in the Free State Province. Hepatotoxicity and electrocardiogram (ECG) deviations were induced in a ...
  • Observations on the clinical, cardiac and histopathological effects of fluoroacetate in sheep 
    Coetzer, Jacobus A.W.; Schultz, R.A. (Rowena Anitra); Kellerman, T. Stephanus; Naude, T.W.; Steyn, P.J.J.; Bigalke, R.D.; Cameron, Colin McKenzie; Gilchrist, Frances M.C.; Jordaan, E.; Morren, A.J.; Verster, Anna J.M.; Verwoerd, Daniel Wynand; Walker, Jane B. (Published by The Government Printer, Pretoria, 1982)
    Fluoroacetate was dosed per stomach tube to 17 Merino sheep at the rate of 0,05 - 1,0 mg/kg/day. The clinical signs, haemodynamic changes, chemical pathology and pathology of acute, subacute and chronically intoxicated ...
  • Perinatal mortality in lambs of ewes exposed to cultures of Diplodia maydis (= Stenocarpella maydis) during gestation 
    Prozesky, Leon; Kellerman, T. Stephanus; Schultz, R.A. (Rowena Anitra); Rabie, C.J.; Van Ark, H.; Maartens, B.P.; Lubben, Annelie; Verwoerd, Daniel Wynand (Published by the Agricultural Research Council, Onderstepoort Veterinary Institute., 1991)
    During 1987 when cob rot was rife, perinatal losses were reported in flocks and herds that had been exposed to diplodiosis. The affected lambs or calves were either stillborn or died soon after birth. Dosing trials at the ...