dc.contributor.author |
Bourhy, H.
|
|
dc.contributor.author |
Kissi, B.
|
|
dc.contributor.author |
Tordo, Noel
|
|
dc.contributor.author |
Rabies in Southern and Eastern Africa. Workshop. (1993, Pretoria, South Africa)
|
|
dc.contributor.editor |
Verwoerd, Daniel Wynand |
|
dc.date.accessioned |
2014-01-27T08:18:41Z |
|
dc.date.available |
2014-01-27T08:18:41Z |
|
dc.date.created |
2013 |
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dc.date.issued |
1993 |
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dc.description |
The articles have been scanned in colour with a HP Scanjet 5590; 600dpi.
Adobe Acrobat XI Pro was used to OCR the text and also for the merging and conversion to the final presentation PDF-format. |
en |
dc.description.abstract |
Currently, the Lyssavirus genus is composed of four serotypes and the ungrouped European bat lyssaviruses (EBL). Using previously described PCR amplification and direct sequencing methods, the N
genes of 70 representative lyssaviruses collected from 40 different countries were examined. From the
results, a phylogenetic tree with six branches (genotypes) was constructed: genotypes 1-4 correlated
with the classification of serotypes 1-4 and in addition EBL 1 and EBL 2 were identified as two further
genotypes (5 and 6). Analysis of the 51 rabies (genotype 1) viruses in the study identified nine distinct
groups which could be correlated with their geographical origins.
A comparison of the six genotypes with four principal Vesiculovirus serotypes showed that their relationship
was closer than that of even the two most closely related Vesiculovirus serotypes.
Antigenic site sequences of isolates from vaccine/treatment failures were similar to vaccine and field
strains, suggesting that failures were not due to genetic variation at the N protein level. |
en |
dc.description.librarian |
mn2014 |
|
dc.identifier.citation |
Bourhy, H, Kissi, B & Tordo, N 1993, 'Taxonomy and evolutionary studies on Lyssaviruses with special reference to Africa’, Onderstepoort Journal of Veterinary Research, vol. 60, no. 4, pp. 277-282. |
en |
dc.identifier.issn |
0330-2465 |
|
dc.identifier.uri |
http://hdl.handle.net/2263/33106 |
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dc.language.iso |
en |
en |
dc.publisher |
Published by the Agricultural Research Council, Onderstepoort Veterinary Institute |
en |
dc.rights |
© ARC-Onderstepoort (original).
© University of Pretoria. Dept of Library Services (digital). |
en |
dc.subject |
Veterinary medicine |
en |
dc.subject |
Rabies in southern and eastern Africa. Proceedings of a workshop held at the Faculty of Veterinary Science, University of Pretoria, Onderstepoort, South Africa, 3-5 May 1993 |
en |
dc.subject |
The molecular epidemiology of African Lyssaviruses |
en |
dc.subject.lcsh |
Veterinary medicine -- South Africa |
|
dc.title |
Taxonomy and evolutionary studies on Lyssaviruses with special reference to Africa |
en |
dc.type |
Other |
en |