Currently, the Lyssavirus genus is composed of four serotypes and the ungrouped European bat lyssaviruses (EBL). Using previously described PCR amplification and direct sequencing methods, the N
genes of 70 representative lyssaviruses collected from 40 different countries were examined. From the
results, a phylogenetic tree with six branches (genotypes) was constructed: genotypes 1-4 correlated
with the classification of serotypes 1-4 and in addition EBL 1 and EBL 2 were identified as two further
genotypes (5 and 6). Analysis of the 51 rabies (genotype 1) viruses in the study identified nine distinct
groups which could be correlated with their geographical origins.
A comparison of the six genotypes with four principal Vesiculovirus serotypes showed that their relationship
was closer than that of even the two most closely related Vesiculovirus serotypes.
Antigenic site sequences of isolates from vaccine/treatment failures were similar to vaccine and field
strains, suggesting that failures were not due to genetic variation at the N protein level.
The articles have been scanned in colour with a HP Scanjet 5590; 600dpi.
Adobe Acrobat XI Pro was used to OCR the text and also for the merging and conversion to the final presentation PDF-format.
Anonymous; Rabies in Southern and Eastern Africa. Workshop. (1993, Pretoria, South Africa); Verwoerd, Daniel Wynand(Published by the Agricultural Research Council, Onderstepoort Veterinary Institute, 1993)
Anonymous; Verwoerd, Daniel Wynand; Thomson, G.R. (Gavin); King, Arthur(Published by the Agricultural Research Council, Onderstepoort Veterinary Institute, 1993)
The papers published in these proceedings were read at a rabies workshop held at Onderstepoort, South Africa on 3-5
May 1993 under the auspices of the Southern and Eastern African Rabies Group (SEARG). The major objectives ...
Faulkner, Katelyn T.; Hurley, Brett Phillip; Robertson, Mark P.; Rouget, Mathieu; Wilson, John R.U.(AOSIS Open Journals, 2017-03-31)
BACKGROUND : Alien organisms are not only introduced from one biogeographical region to
another but also spread within regions. As South Africa shares land borders with six countries,
multiple opportunities exist for the ...