Currently, the Lyssavirus genus is composed of four serotypes and the ungrouped European bat lyssaviruses (EBL). Using previously described PCR amplification and direct sequencing methods, the N
genes of 70 representative lyssaviruses collected from 40 different countries were examined. From the
results, a phylogenetic tree with six branches (genotypes) was constructed: genotypes 1-4 correlated
with the classification of serotypes 1-4 and in addition EBL 1 and EBL 2 were identified as two further
genotypes (5 and 6). Analysis of the 51 rabies (genotype 1) viruses in the study identified nine distinct
groups which could be correlated with their geographical origins.
A comparison of the six genotypes with four principal Vesiculovirus serotypes showed that their relationship
was closer than that of even the two most closely related Vesiculovirus serotypes.
Antigenic site sequences of isolates from vaccine/treatment failures were similar to vaccine and field
strains, suggesting that failures were not due to genetic variation at the N protein level.
The articles have been scanned in colour with a HP Scanjet 5590; 600dpi.
Adobe Acrobat XI Pro was used to OCR the text and also for the merging and conversion to the final presentation PDF-format.
Lotter, Matt Geoffrey; Kuman, Kathleen(Elsevier, 2017-10)
Our understanding of the South African Acheulean is heavily biased towards sites located in the interior of the country, namely in the Cradle of Humankind and those located along the Vaal and Orange Rivers. Although these ...
This dissertation is an attempt to analyse and investigate ways of responding to the poor UPCSA missional approach to Zimbabwean society. The desire to write this dissertation was born out of the experience of working for ...
Cilliers, Jakkie; Schunemann, Julia; Moyer, Jonathan D.(Institute for Security Studies, 2015-03)
This paper explores the changing power capabilities of Algeria, Egypt, Ethiopia,
Nigeria, and South Africa (the ‘Big Five’) over the next 25 years. Of these countries,
Ethiopia and Nigeria are forecast to increase their ...