Browsing Theses and Dissertations (Medical Microbiology) by Subject "Molecular epidemiology"

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Molecular epidemiology and mechanisms of colistin and carbapenem resistance in Enterobacteriaceae from clinical isolates, the environment and porcine samples in Pretoria, South Africa

Bogoshi, Dineo (University of Pretoria, 2020)

Introduction: Carbapenems and colistin are the last-line antibiotics for treating Gram-negative bacterial infections. However, increasing reports of resistance to these antibiotics is being reported in clinical settings, ...
Phenotypic and genotypic characterization of isoniazid resistance mutations in Mycobacterium tuberculosis isolates from new and previously treated patients in the Tshwane region

Sinthumule, Ndivhudzannyi Peace (University of Pretoria, 2020)

Background: Isoniazid (INH) is one of the most potent anti-tuberculosis (TB) drugs and a key component of the multi-drug regimen for the treatment of TB. Tuberculosis cases with initial INH resistance are more at risk ...

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