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Browsing Research Articles (Neurology) by Subject "Parkinson’s disease (PD)"
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Mahne, A.C.; Carr, J.A.; Bardien, S.; Schutte, Clara-Maria
(Health and Medical Publishing Group, 2016-06)
BACKGROUND. Parkinson’s disease (PD), with a prevalence of up to 4% in Western countries, appears to be less common in Africa, possibly
in part because of genetic factors. African studies investigating the genetic causation ...
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Pretorius, Etheresia; Swanepoel, A.C. (Albe Carina); Buys, A.V. (Antonia Vergina); Vermeulen, Natasha; Duim, Wiebren; Kell, Douglas B.
(Impact Journals, 2014-10)
A major trend in recent Parkinson’s disease (PD) research is the investigation of biological markers that could
help in identifying at‐risk individuals or to track disease progression and response to therapies. Central ...
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Du Toit, Nicola; Van Coller, Riaan; Anderson, David G.; Carr, Jonathan; Bardien, Soraya
(Springer, 2019-10)
G2019S in LRRK2 is the most common mutation associated with Parkinson’s disease (PD). Highest frequencies are in North African Arabic (30–41%) and Ashkenazi Jewish (6–30%) populations, mostly due to founder effects. Here, ...
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Carr, Jonathan; Van Coller, Riaan
(Health and Medical Publishing Group, 2014-06)
Neurodegenerative diseases are important causes
of disability and death, with prominent examples
including Alzheimer’s disease, Parkinson’s disease
(PD) and motor neuron disease. Although familial
clustering of these ...
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Mahungu, Amokelani C.; Anderson, David G.; Rossouw, Anastasia C.; Van Coller, Riaan; Carr, Jonathan A.; Ross, Owen A.; Bardien, Soraya
(Elsevier, 2020-04)
Sequence variants in glucocerebrosidase (GBA) are a major genetic risk factor for Parkinson's disease (PD), and display ethnic-dependent frequencies, for example, variants such as p.N370S and 84insGG are common in Ashkenazi ...
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Anderson, D.G.; Van Coller, Riaan; Carr, J.
(Health and Medical Publishing Group, 2017-11)
BACKGROUND : Parkinson’s disease (PD) is a common neurodegenerative disease, associated with severe impairment of quality of life.
Although the motor aspects of the illness are typically successfully treated with medications ...