Human immunodeficiency virus still remains the leading cause of death globally including women of child-bearing age. The rate of AIDS-related death has significantly declined since the introduction of antiretroviral ...

Senescent cells have been linked to age-related diseases and frailty. Their pathogenic effects are mediated by a group of cellular secretions called the senescence-associated secretory phenotype (SASP). Removal of senescent ...

Cervical cancer is the leading cause of cancer-related mortalities in South African women. Vitamin D and its metabolites exert anti-cancer actions in various cancers; however, few studies have explored the effects of vitamin ...

The sudden death (SD) of a young and healthy individual can be traumatic. Approximately 85% of all SD cases are of cardiac origin, a condition known as sudden cardiac death (SCD). Familial dilated cardiomyopathy (FDCM) ...

Please read the abstract on page 3 in the dissertation.

The purpose of this study was to determine whether the methylation of nicotinamide to N-methylnicotinamide could discriminate between differences in methionine nutritional status, and by implication methylation capacity, ...

The endogenous catecholamines and their metabolites play an integral role in establishing the presence or absence of a suspected sympatho-adrenal tumor. Highly elevated metabolites excreted in the urine are indicative of ...

Sudden death can be defined as death from natural causes occurring instantaneous or within a few minutes after its cause (Merriam-Webster, 2019). It is globally considered as one of the leading causes of mortality and may ...