Browsing Nuclear Medicine by Author "Verbeke, Frederick"

Browsing Nuclear Medicine by Author "Verbeke, Frederick"

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  • Biological characterisation of somatropin-derived cryptic peptides 
    Tack, Liesa; Bracke, Nathalie; Verbeke, Frederick; Wynendaele, Evelien; Pauwels, Ewald; Maes, Alex; Van de Wiele, Christophe; Sathekge, Mike Machaba; De Spiegeleer, Bart (Springer, 2019-09)
    Little is known about possible cryptic peptides of the recombinant growth hormone (somatropin). In this study, six synthetic somatropin-derived peptides (SDPs) were selected based on their sequences which correspond to the ...
  • Crosstalk between the microbiome and cancer cells by quorum sensing peptides 
    Wynendaele, Evelien; Verbeke, Frederick; D’Hondt, Matthias; Hendrix, An; Van de Wiele, Christophe; Burvenich, Christian; Peremans, Kathelijne; De Wever, Olivier; Bracke, Marc; De Spiegeleer, Bart (Elsevier, 2015-02)
    To date, the precise role of the human microbiome in health and disease states remains largely undefined. Complex and selective crosstalk systems between the microbiome and mammalian cells are also not yet reported. ...
  • In vitro functional quality characterization of NOTA-modified somatropins 
    Bracke, Nathalie; Yao, Han; Wynendaele, Evelien; Verbeke, Frederick; Xu, Xiaolong; Gevaert, Bert; Maes, Alex; Van de Wiele, Christophe; Sathekge, Mike Machaba; De Saeger, Sarah; De Spiegeleer, Bart (American Chemical Society, 2017-03)
    Chemical modifications on protein biopharmaceuticals introduce extra variability in addition to their inherent complexity, hence require more comprehensive analytical and functional characterization during their discovery, ...
  • The quorum sensing peptides PhrG, CSP and EDP promote angiogenesis and invasion of breast cancer cells in vitro 
    De Spiegeleer, Bart; Verbeke, Frederick; D’Hondt, Matthias; Hendrix, An; Van de Wiele, Christophe; Burvenich, Christian; Peremans, Kathelijne; De Wever, Olivier; Bracke, Marc; Wynendaele, Evelien (Public Library of Science, 2015-03-17)
    The role of the human microbiome on cancer progression remains unclear. Therefore, in this study, we investigated the influence of some quorum sensing peptides, produced by diverse commensal or pathogenic bacteria, on ...