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Browsing Research Articles (Obstetrics and Gynaecology) by UP Author "Dreyer, Greta"
Now showing items 1-20 of 52
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Punchoo, Rivak; Dreyer, Greta; Pillay, Tahir S. (MDPI, 2023-03)Preclinical studies show that the anticancer actions of vitamin D metabolites are mediated by apoptosis, inhibition of cell proliferation and induction of cell cycle arrest. Cervical cancer cells express an autocrine vitamin ...
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Hapsari, Kartika; Makin, J.D. (Jennifer Dianne); Dreyer, Greta (Medpharm Publications, NISC (Pty) and Cogent, Taylor and Francis Group, 2019)BACKGROUND: The purpose of the study was to evaluate the predictive value of serum CA-125 levels in the preoperative assessment of endometrial carcinoma in a setting where late presentation is common. METHOD: This ...
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Schlebusch, Carina M.; Dreyer, Greta; Sluiter, M.D.; Yawitch, T.M.; Van den Berg, H.J.; Jansen van Rensburg, Elizabeth (Health and Medical Publishing Group, 2010-02)BACKGROUND: Women who carry germline mutations in the breast-ovarian cancer susceptibility genes, BRCA1 and BRCA2, are at very high risk of developing breast and / or ovarian cancer. Both genes are tumour suppressor genes ...
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Botha, Hennie; Cooreman, Bruno; Dreyer, Greta; Lindeque, B. Gerhard; Mouton, Arrie; Guidozzi, Franco; Koller, Tony; Smith, Trudy; Hoosen, Anwar Ahmed; Marcus, Louis; Moodley, Manivasan; Soeters, Robbie (Open Journals Systems, 2010)Cervical carcinoma is still the most common cancer of women on the African continent. Mortality remains high – worldwide at 50% – mainly because of late presentation, advanced stage of disease and absence of a functioning ...
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Botha, Hennie; Cooreman, Bruno; Dreyer, Greta; Lindeque, B. Gerhard; Mouton, Arrie; Guidozzi, Franco; Koller, Tony; Smith, Trudy; Hoosen, Anwar Ahmed; Marcus, Louis; Moodley, Manivasan; Soeters, Robbie (Open Journals Systems, 2010)No abstract available.
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Tapera, Oscar; Dreyer, Greta; Kadzatsa, W.; Nyakabau, A.M.; Stray-Pedersen, B.; Hendricks, S.J.H. (BioMed Central, 2019-07-08)BACKGROUND : Cervical cancer is the most common cancer and a major cause of morbidity and mortality among women in Zimbabwe yet it is preventable, early detectable and highly curable. The objective of this study was ...
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Dreyer, Greta; Mnisi, E.F.; Maphalala, A. (Open Journals Systems, 2013)OBJECTIVES: The aim was to identify challenges to conducting research and obstacles to successful cervical cancer screening in public sector primary healthcare clinics (PHCs). DESIGN: Qualitative research was conducted, ...
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Dreyer, Greta; Maske, Christopher; Stander, Marthinus (BioMed Central, 2019-09-11)Cytology remains the mainstay of cervical cancer screening in South Africa (SA), however false negative rates are 25–50%. In contrast, human papillomavirus (HPV) screening techniques have higher sensitivity for cervical ...
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Dreyer, Greta (Elsevier, 2018-02)HIV-related immunodeficiency has complex effects on female genital HPV, which include increased risks of infection, multiple types, persistence, reactivation and the risk to develop pre-invasive and invasive disease. ...
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Dreyer, Greta; Botha, Matthys H.; Snyman, Leon Cornelius; Visser, Cathy; Burden, Riekie; Laubscher, Nicolene; Grond, Bertha; Richter, Karin Louise; Becker, Piet J.; Harvey, Justin; Van der Merwe, Frederick H. (BMJ Publishing Group, 2022-05)OBJECTIVE : The platform provided by human papillomavirus (HPV) vaccination for linked public health interventions to improve cervical cancer prevention remains incompletely explored. The Vaccine And Cervical Cancer Screen ...
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Vijayaraghavan, Arthi; Efrusy, Molly; Lindeque, B. Gerhard; Dreyer, Greta; Santas, Christopher (Elsevier, 2009)OBJECTIVE. To determine the cost effectiveness of several cervical cancer screening strategies utilizing HPV testing in South Africa. METHODS. We developed a lifetime Markov model of the costs, quality of life, and survival ...
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Snyman, Leon Cornelius; Richter, Karin Louise; widowi; Dreyer, Gerrit; Botha, Matthys Hendrik; Van der Merwe, F. Haynes; Visser, Cathy; Dreyer, Greta (BMJ Publishing, 2023-05)OBJECTIVES : Cervical cancer is preventable and caused by persistent infection with oncogenic human papilloma virus (HPV) types. HPV screening is more sensitive and is the preferred screening test. HPV screening data are ...
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Tapera, Oscar; Dreyer, Greta; Stray-Pedersen, Babill; Hendricks, Stephen James Heinrich (Canadian Center of Science and Education, 2019)BACKGROUND : Standardized tools to evaluate access and utilization of cervical cancer treatment and care remain scarce in developing countries. The objective of this study was to validate questionnaires to investigate ...
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Kremer, Wieke W.; Van Zummeren, Marjolein; Novianti, Putri W.; Richter, Karin Louise; Verlaat, Wina; Snijders, Peter J.F.; Heideman, Danielle A.M.; Steenbergen, Renske D.M.; Dreyer, Greta; Meijer, Chris J.L.M. (Wiley Open Access, 2018-08)INTRODUCTION : To evaluate the performance of hypermethylation analysis of ASCL1, LHX8 and ST6GALNAC5 in physician-taken cervical scrapes for detection of cervical cancer and cervical intraepithelial neoplasia (CIN) grade ...
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Tapera, Oscar; Dreyer, Greta; Kadzatsa, W.; Nyakabau, A.M.; Stray-Pedersen, B.; Hendricks, S.J.H. (BioMed Central, 2019-07-29)BACKGROUND : Cervical cancer treatment and care services have remained largely centralized in Zimbabwe thereby entrenching inequities to access amongst patients. The objective of this study was to investigate the ...
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Snyman, Leon Cornelius; Dreyer, Greta (Open Journals Systems, 2013)OBJECTIVES: Despite a shift towards other screening modalities, cervical cytology still has an important screening function in many settings. The worldwide human immunodeficiency virus (HIV) epidemic has impacted severely on ...
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Sorbye, Sveinung Wergeland; Falang, Bente Marie; Botha, Matthys H.; Snyman, Leon Cornelius; Van der Merwe, Haynes; Visser, Cathy; Richter, Karin Louise; Dreyer, Greta (MDPI, 2023-11-17)BACKGROUND : Cervical cancer prevention in regions with limited access to screening and HPV vaccination necessitates innovative approaches. This study explored the potential of a test-and-treat strategy using mRNA HPV tests ...
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Dreyer, Greta (Open Journals Systems, 2010)The diagnosis of inherited cancer-susceptibility syndromes can enable identification of individuals at increased risk for earlyonset cancer. The treatment and prognosis of patients diagnosed with malignancy due to a germ-line ...
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Makhathini, Bongumusa S.; Dreyer, Greta; Buchmann, Eckhart J. (Medpharm Publications, NISC (Pty) and Cogent, Taylor and Francis Group, 2019)BACKGROUND: A study was undertaken to describe the outcomes of gestational trophoblastic disease (GTD) and to determine the influence of antecedent pregnancy, the distance travelled by patients to Grey’s Hospital (GH), ...
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Tapera, Oscar; Dreyer, Greta; Kadzatsa, W.; Nyakabau, A.M.; Stray-Pedersen, B.; Hendricks, S.J.H. (BioMed Central, 2019-11-19)BACKGROUND : Cervical cancer is a major cause of morbidity and mortality among women yet access to treatment and care remains a huge challenge in Zimbabwe. The objective of this study was to investigate health system constraints ...
Now showing items 1-20 of 52