Research Articles (Obstetrics and Gynaecology)

Research Articles (Obstetrics and Gynaecology)

 

Recent Submissions

  • Moetlediwa, Marakiya T.; Ramashia, Rudzani; Pheiffer, Carmen; Titinchi, Salam J. J.; Mazibuko-Mbeje, Sithandiwe E.; Jack, Babalwa U. (MDPI, 2023-09)
    Obesity is a major cause of morbidity and mortality globally, increasing the risk for chronic diseases. Thus, the need to identify more effective anti-obesity agents has spurred significant interest in the health-promoting ...
  • Jack, Babalwa Unice; Ramharack, Pritika; Malherbe, Christiaan; Gabuza, Kwazi; Joubert, Elizabeth; Pheiffer, Carmen (MDPI, 2023-02)
    Previously, we reported that a crude polyphenol-enriched fraction of Cyclopia intermedia (CPEF), a plant consumed as the herbal tea, commonly known as honeybush, reduced lipid content in 3T3-L1 adipocytes and inhibited ...
  • Vink, Frederique J.; Meijer, Chris J.L.M.; Lissenberg-Witte, Birgit I.; Visser, Cathy; Duin, Sylvia; Snyman, Leon Cornelius; Richter, Karin Louise; Van der Merwe, Frederick H.; Botha, Matthys H.; Steenbergen, Renske D.M.; Dreyer, Greta (Oxford University Press, 2023-02-01)
    BACKGROUND : Compared with women who are human immunodeficiency virus (HIV) negative, women with human immunodeficiency virus (WWH) have a higher human papillomavirus (HPV) prevalence and increased cervical cancer ...
  • Sorbye, Sveinung Wergeland; Falang, Bente Marie; Botha, Matthys H.; Snyman, Leon Cornelius; Van der Merwe, Haynes; Visser, Cathy; Richter, Karin Louise; Dreyer, Greta (MDPI, 2023-11-17)
    BACKGROUND : Cervical cancer prevention in regions with limited access to screening and HPV vaccination necessitates innovative approaches. This study explored the potential of a test-and-treat strategy using mRNA HPV tests ...
  • Anakwenze, Chidinma P.; Allanson, Emma; Ewongwo, Agnes; Lumley, Christian; Bazzett-Matabele, Lisa; Msadabwe, Susan C.; Kamfwa, Paul; Shouman, Tarek; Lombe, Dorothy; Rubagumya, Fidel; Polo, Alfredo; Ntekim, Atara; Vanderpuye, Verna; Ghebre, Rahel; Kochbati, Lofti; Awol, Munir; Gnangnon, Freddy Houehanou Rodrigue; Snyman, Leon Cornelius; Domgue, Joel Fokom; Incrocci, Luca; Ndlovu, Ntokozo; Razakanaivo, Malala; Abdel-Wahab, May; Trimble, Edward; Schmeler, Kathleen; Simonds, Hannah; Grover, Surbhi (Elsevier, 2024-03)
    PURPOSE: To meet the demand for cervical cancer care in Africa, access to surgical and radiation therapy services needs to be understood. We thus mapped the availability of gynecologic and radiation therapy equipment and ...
  • Malaza, Nompumelelo; Pheiffer, Carmen; Dias, S.; Adam, Sumaiya (Health and Medical Publishing Group, 2023-06)
    BACKGROUND : Diabetes and obesity in pregnancy have been associated with increased rates of adverse maternal and neonatal outcomes compared with women with normoglycaemia and normal weight. OBJECTIVE : To investigate the ...
  • Betrán, Ana Pilar; Torloni, Maria Regina; Althabe, Fernando; Altieri, Elena; Arulkumaran, Sabaratnam; Ashraf, Fatema; Bailey, Patricia; Bucagu, Maurice; Clark, Emma; Changizi, Nasrin; Churchill, Robyn; Dominico, Sunday; Downe, Soo; Draycott, Tim; Faye, Arfang; Feeley, Claire; Geelhoed, Diederike; Gherissi, Atf; Gholbzouri, Karima; Grupta, Gagan; Hailegebriel, Tedbabe Degefie; Hanson, Claudia; Hartmann, Katharina; Hassan, Lubna; Hofmeyr, George Justus; Jayathilaka, Anoma Chandani; Kabore, Charles; Kidula, Nancy; Kingdon, Carol; Kuzmenko, Oleg; Lumbiganon, Pisake; Mola, Glen D.L.; Moran, Allisyn; De Muncio, Bremen; Nolens, Barbara; Opiyo, Newton; Pattinson, Robert Clive; Romero, Mariana; Van Roosmalen, Jos; Siaulys, Monica M.; Camelo, Jose Simon; Smith, Jeffrey; Sobel, Howard L.; Sobhy, Soha; Sosa, Claudio; Souza, Joao Paulo; Hoope-Bender, Petra Ten; Thangaratinam, Shakila; Varallo, John; Wright, Alison; Yates, Ann; Oladapo, Olufemi O. (World Health Organization, 2023-11)
    Access to emergency obstetric care, including assisted vaginal birth and caesarean birth, is crucial for improving maternal and childbirth outcomes. However, although the proportion of births by caesarean section has ...
  • Hlongwane, T.M.A.G. (Tsakane); Pattinson, Robert Clive; Bergh, Anne-Marie (BMC, 2023-05-27)
    INTRODUCTION : Detecting the risk of stillbirth during pregnancy remains a challenge. Continuous-wave Doppler ultrasound (CWDU) can be used to screen for placental insufficiency, which is a major cause of stillbirths in ...
  • Abrahams, Yoonus; Willmer, Tarryn; Patel, Oelfah; Samodien, Ebrahim; Muller, Christo J.F.; Windvogel, Shantal; Johnson, Rabia; Pheiffer, Carmen (Elsevier, 2023-11)
    Previously we reported that a high fat, high sugar (HFHS) diet induced adiposity, hyperinsulinaemia, hyperleptinaemia, hypertriglyceridaemia and increased liver mass in male Wistar rats. In the present study, the mechanisms ...
  • Botha, Matthys Hendrik; Van der Merwe, Frederick H.; Snyman, Leon Cornelius; Dreyer, Gerrit J.; Visser, Cathy; Dreyer, Greta (Lippincott, Williams & Wilkins, 2023-07)
    OBJECTIVE : Screening with primary human papillomavirus (HPV) testing has been evaluated in highly prescreened populations with lower HPV and HIV prevalence than what is the case in South Africa. High prevalence of HPV and ...
  • Nel, Sanja; Pattinson, Robert Clive; Vannevel, Valerie; Feucht, Ute; Mulol, Helen; Wenhold, F.A.M. (Friedeburg Anna Maria) (Cambridge University Press, 2023-08)
    OBJECTIVES : Prenatal growth affects short- and long-term morbidity, mortality and growth, yet communication between prenatal and postnatal healthcare teams is often minimal. This paper aims to develop an integrated, ...
  • Bhorat, I.; Buchmann, E.; Soma-Pillay, Priya; Nicolaou, E.; Pistorius, L.; Smuts, Izelle; Velaphi, S. (South African Medical Association, 2023-07)
    The objective of this study was to establish scientific causality and to devise criteria to implicate intrapartum hypoxia in cerebral palsy (CP) in low-resource settings, where there is potential for an increase in damaging ...
  • Snyman, Leon Cornelius; Richter, Karin Louise; widowi; Dreyer, Gerrit; Botha, Matthys Hendrik; Van der Merwe, F. Haynes; Visser, Cathy; Dreyer, Greta (BMJ Publishing, 2023-05)
    OBJECTIVES : Cervical cancer is preventable and caused by persistent infection with oncogenic human papilloma virus (HPV) types. HPV screening is more sensitive and is the preferred screening test. HPV screening data are ...
  • Punchoo, Rivak; Dreyer, Greta; Pillay, Tahir S. (MDPI, 2023-03)
    Preclinical studies show that the anticancer actions of vitamin D metabolites are mediated by apoptosis, inhibition of cell proliferation and induction of cell cycle arrest. Cervical cancer cells express an autocrine vitamin ...
  • Rimmer, Michael P.; Howie, Ruth A.; Anderson, Richard A.; Barratt, Christopher L.R.; Barnhart, Kurt T.; Beebeejaun, Yusuf; Bertolla, Ricardo Pimenta; Bhattacharya, Siladitya; Bjorndahl, Lars; Bortoletto, Pietro; Brannigan, Robert E.; Cantineau, Astrid E.P.; Caroppo, Ettore; Collura, Barbara L.; Coward, Kevin; Eisenberg, Michael L.; De Geyter, Christian; Goulis, Dimitrios G.; Henkel, Ralf R.; Ho, Vu N.A.; Hussein, Alayman F.; Huyser, Carin; Kadijk, Jozef H.; Kamath, Mohan S.; Khashaba, Shadi; Kobori, Yoshitomo; Kopeika, Julia; Kucuk, Tansu; Lujan, Saturnino; Matsaseng, Thabo Christopher; Mathur, Raj S.; McEleny, Kevin; Mitchell, Rod T.; Mol, Ben W.; Murage, Alfred M.; Ng, Ernest H.Y.; Pacey, Allan; Perheentupa, Antti H.; Du Plessis, Stefan; Rives, Nathalie; Sarris, Ippokratis; Schlegel, Peter N.; Shabbir, Majid; Smiechowski, Maciej; Subramanian, Venkatesh; Sunkara, Sesh K.; Tarlarzis, Basil C.; Tuttelmann, Frank; Tuttelmann, Frank; Vail, Andy; Van Wely, Madelon; Vazquez-Levin, Monica H.; Vuong, Lan N.; Alex Y. Wang; Wang, Rui; Zini, Armand; Farquhar, Cindy M.; Niederberger, Craig; Duffy, James M.N. (Oxford University Press, 2022-03)
    STUDY QUESTION : We aim to develop, disseminate and implement a minimum data set, known as a core outcome set, for future male infertility research. WHAT IS KNOWN ALREADY : Research into male infertility can be challenging ...
  • Nachega, Jean B.; Sam-Agudu, Nadia A.; Machekano, Rhoderick N.; Rosenthal, Philip J.; Schell, Sonja; De Waard, Liesl; Bekker, Adrie; Gachuno, Onesmus W.; Kinuthia, John; Mwongeli, Nancy; Budhram, Samantha; Vannevel, Valerie; Soma-Pillay, Priya; Prozesky, Hans W.; Taljaard, Jantjie; Parker, Arifa; Agyare, Elizabeth; Opoku, Akwasi Baafuor; Makarfi, Aminatu Umar; Abdullahi, Asara M.; Adirieje, Chibueze; Ishoso, Daniel Katuashi; Pipo, Michel Tshiasuma; Tshilanda, Marc B.; Nswe, Christian Bongo-Pasi; Ditekemena, John; Sigwadhi, Lovemore Nyasha; Nyasulu, Peter S.; Hermans, Michel P.; Sekikubo, Musa; Musoke, Philippa; Nsereko, Christopher; Agbeno, Evans K.; Yeboah, Michael Yaw; Umar, Lawal W.; Ntakwinja, Mukanire; Mukwege, Denis M.; Birindwa, Etienne Kajibwami; Mushamuka, Serge Zigabe; Smith, Emily R.; Mills, Edward J.; Otshudiema, John Otokoye; Mbala-Kingebeni, Placide; Tamfum, Jean-Jacques Muyembe; Zumla, Alimuddin; Tsegaye, Aster; Mteta, Alfred; Sewankambo, Nelson K.; Suleman, Fatima; Adejumo, Prisca; Anderson, Jean R.; Noormahomed, Emilia V.; Deckelbaum, Richard J.; Stringer, Jeffrey S.A.; Mukalay, Abdon; Taha, Taha E.; Fowler, Mary Glenn; Wasserheit, Judith N.; Masekela, Refiloe; Mellors, John W.; Siedner, Mark J.; Myer, Landon; Kengne, Andre-Pascal; Yotebieng, Marcel; Mofenson, Lynne M.; Langenegger, Eduard; AFREhealth Research Collaboration on COVID-19 and Pregnancy (Oxford University Press, 2022-06-08)
    BACKGROUND : Few data are available on COVID-19 outcomes among pregnant women in sub-Saharan Africa (SSA), where high-risk comorbidities are prevalent. We investigated the impact of pregnancy on SARS-CoV-2 infection and ...
  • Olivier, H.J.; Snyman, Leon Cornelius; Oliva, E.; Slavik, Tomas (MedPharm Publications, 2022-12)
    The presence of squamous cell carcinoma (SCC) on endometrial histology raises the possibility of a primary endometrial carcinoma, as well as secondary endometrial involvement by SCC from another site, especially the cervix. ...
  • Jackson, Hayley C.; Pheiffer, Carmen; Jack, Babalwa; Africander, Donita (Elsevier, 2023-09)
    The 3T3-L1 murine adipocyte cell line remains one of the most widely used models to study the mechanisms of obesity and related pathologies. Most studies investigate such mechanisms using mature adipocytes that have been ...
  • Soma-Pillay, Priya; Wium, L.; Pillay, Yogan (Netherlands Press, 2022-11)
    It can be argued that there are three colliding pandemics that are currently affecting the planet and its people: COVID-19, global inequities and climate change. Regrettably, these are all the result of human action or ...
  • Dreyer, Greta; Zondagh, Jake (Netherlands Press, 2022-01)
    The importance of iron for overall health in humans cannot be overstated and its extremely widespread biological functions include electron transfer, intercellular signalling, catalysis, and oxygen binding and transport. ...

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