Browsing Research Articles (Obstetrics and Gynaecology) by Author "Johnson, Rabia"

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A high fat, high sugar diet induces hepatic peroxisome proliferator-activated receptor gamma coactivator 1-alpha promoter hypermethylation in male Wistar rats

Abrahams, Yoonus; Willmer, Tarryn; Patel, Oelfah; Samodien, Ebrahim; Muller, Christo J.F.; Windvogel, Shantal; Johnson, Rabia; Pheiffer, Carmen (Elsevier, 2023-11)

Previously we reported that a high fat, high sugar (HFHS) diet induced adiposity, hyperinsulinaemia, hyperleptinaemia, hypertriglyceridaemia and increased liver mass in male Wistar rats. In the present study, the mechanisms ...
Intestinal barrier function and immune homeostasis are missing links in obesity and type 2 diabetes development

Riedel, Sylvia; Pheiffer, Carmen; Johnson, Rabia; Louw, Johan; Muller, Christo J. F. (Frontiers Media S.A., 2022-01-25)

Noncommunicable diseases, such as type 2 diabetes (T2D), place a burden on healthcare systems worldwide. The rising prevalence of obesity, a major risk factor for T2D, is mainly attributed to the adoption of Westernized ...

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