Browsing Research Articles (Obstetrics and Gynaecology) by Author "Bates, David Owen"

Browsing Research Articles (Obstetrics and Gynaecology) by Author "Bates, David Owen"

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  • Apoptosis in cancer cells is induced by alternative splicing of hnRNPA2/B1 through splicing of Bcl-x, a mechanism that can be stimulated by an extract of the South African medicinal plant, Cotyledon orbiculata 
    Makhafola, Tshepiso Jan; Mbele, Mzwandile; Yacqub-Usman, Kiren; Hendren, Amy; Haigh, Daisy Belle; Blackley, Zoe; Meyer, Mervin; Mongan, Nigel Patrick; Bates, David Owen; Dlamini, Zodwa (Frontiers Media, 2020-10)
    Alternative splicing is deregulated in cancer and alternatively spliced products can be linked to cancer hallmarks. Targeting alternative splicing could offer novel effective cancer treatments. We investigated the effects ...
  • Cervical cancer in low and middle‑income countries 
    Hull, Rodney; Mbele, Mzwandile; Makhafola, Tshepiso Jan; Hicks, Chindo; Wang, Shao Ming; Reis, Rui Manuels; Mehrotra, Ravi; Mkhize-Kwitshana, Zilungile; Kibiki, Gibson; Bates, David Owen; Dlamini, Zodwa (Spandidos, 2020)
    Cervical cancer is a malignant tumour that occurs in the cervix and is classified into two histological types, adenocarcinoma and squamous cell carcinoma (SCC); SCC is more common and accounts for 70% of all cases. In 2018 ...
  • Impaired vascular permeability regulation caused by the VEGF165b splice variant in pre-eclampsia 
    Bills, Victoria L.; Salmon, Andrew H.; Harper, Steven J.; Overton, Tim G.; Neal, Chris R.; Jeffery, Bridget; Soothill, Peter W.; Bates, David Owen (Wiley-Blackwell, 2011-09)
    OBJECTIVE: Pre-eclampsia is diagnosed by hypertension and proteinuria, probably caused by endothelial dysfunction, resulting in symptoms including oedema, inflammation and altered metabolism. Vascular endothelial growth ...
  • A multinational review : oesophageal cancer in low to middle-income countries 
    Hull, Rodney; Mbele, Mzwandile; Makhafola, Tshepiso Jan; Hicks, Chindo; Wang, Shao Ming; Reis, Rui Manuels; Mehrotra, Ravi; Mkhize-Kwitshana, Zilungile; Hussain, Showket; Kibiki, Gibson; Bates, David Owen; Dlamini, Zodwa (Spandidos, 2020-10)
    Oesophageal cancer (OC) is an aggressive neoplasm that manifests in the gastrointestinal tract and is the result of numerous factors that can contribute to the development of the disease. These may include old age, nutritional ...